The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function

scientific article published on 27 May 2008

The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.CEB.2008.03.015
P698PubMed publication ID18511251
P5875ResearchGate publication ID5340168

P2093author name stringVladimir Marshansky
Masamitsu Futai
P2860cites workMutations in the gene encoding B1 subunit of H+-ATPase cause renal tubular acidosis with sensorineural deafnessQ22008703
Negative factor from SIV binds to the catalytic subunit of the V-ATPase to internalize CD4 and to increase viral infectivityQ24290827
Subunit H of the V-ATPase binds to the medium chain of adaptor protein complex 2 and connects Nef to the endocytic machineryQ24298213
Vacuolar H+-ATPase d2 subunit: molecular characterization, developmental regulation, and localization to specialized proton pumps in kidney and boneQ24299288
V1 and V0 domains of the human H+-ATPase are linked by an interaction between the G and a subunitsQ24300220
V-ATPase interacts with ARNO and Arf6 in early endosomes and regulates the protein degradative pathwayQ24301314
Physical interaction between aldolase and vacuolar H+-ATPase is essential for the assembly and activity of the proton pumpQ24311929
Subunit H of the V-ATPase involved in endocytosis shows homology to beta-adaptinsQ24531411
An endosomal beta COP is involved in the pH-dependent formation of transport vesicles destined for late endosomesQ24671983
Membrane insertion of anthrax protective antigen and cytoplasmic delivery of lethal factor occur at different stages of the endocytic pathwayQ24676355
Yeast V-ATPase complexes containing different isoforms of the 100-kDa a-subunit differ in coupling efficiency and in vivo dissociationQ27932441
The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis.Q27939014
Defects in TCIRG1 subunit of the vacuolar proton pump are responsible for a subset of human autosomal recessive osteopetrosisQ28140437
Mutations in the a3 subunit of the vacuolar H(+)-ATPase cause infantile malignant osteopetrosisQ28143618
Molecular cloning and characterization of novel tissue-specific isoforms of the human vacuolar H(+)-ATPase C, G and d subunits, and their evaluation in autosomal recessive distal renal tubular acidosisQ28207921
Revised nomenclature for mammalian vacuolar-type H+ -ATPase subunit genesQ28212690
The vacuolar (H+)-ATPases--nature's most versatile proton pumpsQ28218190
Mechanisms of pathogen entry through the endosomal compartmentsQ28245917
The GTPase superfamily: a conserved switch for diverse cell functionsQ28302983
Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunitsQ28505548
Differential localization of the vacuolar H+ pump with G subunit isoforms (G1 and G2) in mouse neuronsQ28511629
Distinct expression patterns of different subunit isoforms of the V-ATPase in the rat epididymisQ28566043
Differential expression and targeting of endogenous Arf1 and Arf6 small GTPases in kidney epithelial cells in situQ28569209
a4, a unique kidney-specific isoform of mouse vacuolar H+-ATPase subunit aQ28586680
Molecular cloning and characterization of Atp6n1b: a novel fourth murine vacuolar H+-ATPase a-subunit geneQ28592105
Three subunit a isoforms of mouse vacuolar H(+)-ATPase. Preferential expression of the a3 isoform during osteoclast differentiationQ28594187
A proton pump ATPase with testis-specific E1-subunit isoform required for acrosome acidificationQ28595083
Vacuolar ATPases: rotary proton pumps in physiology and pathophysiologyQ29614686
The mechanisms of vesicle budding and fusionQ29615234
Ceramide triggers budding of exosome vesicles into multivesicular endosomesQ29616811
ARF proteins: roles in membrane traffic and beyondQ29618078
Regulation of actin cytoskeleton dynamics by Arf-family GTPasesQ30435862
Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H+-ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.Q33694769
The road taken: past and future foundations of membrane trafficQ33824729
Mechanically driven ATP synthesis by F1-ATPaseQ34293489
Seventeen a-subunit isoforms of paramecium V-ATPase provide high specialization in localization and functionQ34325793
Renal vacuolar H+-ATPaseQ34350645
The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila.Q34420273
The V-type H+ ATPase: molecular structure and function, physiological roles and regulationQ34651704
Impaired glycosylation and cutis laxa caused by mutations in the vesicular H+-ATPase subunit ATP6V0A2.Q34729925
Physiological importance of endosomal acidification: potential role in proximal tubulopathiesQ34789735
The importance of being acid: the role of acidification in intracellular membrane trafficQ35663657
In situ measurement of the electrical potential across the phagosomal membrane using FRET and its contribution to the proton-motive forceQ35839672
Diverse and essential roles of mammalian vacuolar-type proton pump ATPase: toward the physiological understanding of inside acidic compartmentsQ35849771
Role of the V-ATPase in regulation of the vacuolar fission-fusion equilibriumQ36016989
The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegansQ36117665
The where, when, and how of organelle acidification by the yeast vacuolar H+-ATPaseQ36416690
New insights into the regulation of V-ATPase-dependent proton secretionQ36619911
Cellular environment is important in controlling V-ATPase dissociation and its dependence on activityQ36672123
Bicarbonate-regulated Adenylyl Cyclase (sAC) Is a Sensor That Regulates pH-dependent V-ATPase RecyclingQ36838890
Emerging roles of alkali cation/proton exchangers in organellar homeostasisQ36889613
Regulation of vacuolar pH and its modulation by some microbial speciesQ36931418
The V-ATPase a2-subunit as a putative endosomal pH-sensorQ36979618
Acidic endomembrane organelles are required for mouse postimplantation developmentQ38458299
Voltage-dependent electrogenic chloride/proton exchange by endosomal CLC proteinsQ40395142
Traffic jams II: an update of diseases of intracellular transportQ40626944
From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiationQ40658848
Chloride concentration in endosomes measured using a ratioable fluorescent Cl- indicator: evidence for chloride accumulation during acidificationQ40763813
Vacuolar ATPase activity is required for endosomal carrier vesicle formationQ41495121
An expanded and flexible form of the vacuolar ATPase membrane sectorQ41625913
Vacuole membrane fusion: V0 functions after trans-SNARE pairing and is coupled to the Ca2+-releasing channelQ41875865
Involvement of the nonhomologous region of subunit A of the yeast V-ATPase in coupling and in vivo dissociationQ41913510
V-ATPase V0 sector subunit a1 in neurons is a target of calmodulinQ41939791
Four subunit a isoforms of Caenorhabditis elegans vacuolar H+-ATPase. Cell-specific expression during developmentQ43664657
ARNO but not cytohesin-1 translocation is phosphatidylinositol 3-kinase-dependent in HL-60 cells.Q43943403
Activation of lysosomal function during dendritic cell maturationQ44333919
Subunit rotation of vacuolar-type proton pumping ATPase: relative rotation of the G and C subunitsQ44387465
Expression and function of the mouse V-ATPase d subunit isoformsQ44578323
Specific sorting of the a1 isoform of the V-H+ATPase a subunit to nerve terminals where it associates with both synaptic vesicles and the presynaptic plasma membraneQ44644021
Vacuolar H+-ATPase binding to microfilaments: regulation in response to phosphatidylinositol 3-kinase activity and detailed characterization of the actin-binding site in subunit B.Q44684932
The glycolytic enzyme aldolase mediates assembly, expression, and activity of vacuolar H+-ATPaseQ44691509
Differential expression of a subunit isoforms of the vacuolar-type proton pump ATPase in mouse endocrine tissuesQ48170696
PI-3-kinase-dependent membrane recruitment of centaurin-alpha2 is essential for its effect on ARF6-mediated actin cytoskeleton reorganisation.Q50698333
Molecular cloning and expression of three isoforms of the 100-kDa a subunit of the mouse vacuolar proton-translocating ATPase.Q52170550
Chloride and the endosomal-lysosomal pathway: emerging roles of CLC chloride transporters.Q52575042
Mouse proton pump ATPase C subunit isoforms (C2-a and C2-b) specifically expressed in kidney and lung.Q54757837
Differential requirement for the translocation of clostridial binary toxins: Iota toxin requires a membrane potential gradientQ57360832
Trans-complex formation by proteolipid channels in the terminal phase of membrane fusionQ59067778
V-ATPase: a potential pH sensorQ64019143
ARF: a key regulatory switch in membrane traffic and organelle structureQ72872226
Mechanical rotation of the c subunit oligomer in ATP synthase (F0F1): direct observationQ73216171
The gene encoding the mouse homologue of the human osteoclast-specific 116-kDa V-ATPase subunit bears a deletion in osteosclerotic (oc/oc) mutantsQ73531419
ARF1 regulates pH-dependent COP functions in the early endocytic pathwayQ73538511
Intra-endosomal pH-sensitive recruitment of the Arf-nucleotide exchange factor ARNO and Arf6 from cytoplasm to proximal tubule endosomesQ73694156
The a3 isoform of V-ATPase regulates insulin secretion from pancreatic beta-cellsQ79259889
v-ATPase V0 subunit d2-deficient mice exhibit impaired osteoclast fusion and increased bone formationQ79383955
Rotational catalysis of Escherichia coli ATP synthase F1 sector. Stochastic fluctuation and a key domain of the beta subunitQ80367697
P433issue4
P304page(s)415-426
P577publication date2008-05-27
P1433published inCurrent Opinion in Cell BiologyQ13505682
P1476titleThe V-type H+-ATPase in vesicular trafficking: targeting, regulation and function
P478volume20

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Q38944928Triterpenoid saponin augmention of saporin-based immunotoxin cytotoxicity for human leukaemia and lymphoma cells is partially immunospecific and target molecule dependent
Q87441832Urothelial endocytic vesicle recycling and lysosomal degradative pathway regulated by lipid membrane composition
Q89656175V-ATPase a3 isoform mutations identified in osteopetrosis patients abolish its expression and disrupt osteoclast function
Q36998413V-ATPase activity in the TGN/EE is required for exocytosis and recycling in Arabidopsis
Q39093549V-ATPase inhibition overcomes trastuzumab resistance in breast cancer
Q39435290V-ATPase promotes transforming growth factor-β-induced epithelial-mesenchymal transition of rat proximal tubular epithelial cells
Q28506518V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption
Q35551874Vacuolar ATPase 'a2' isoform exhibits distinct cell surface accumulation and modulates matrix metalloproteinase activity in ovarian cancer
Q42650754Vacuolar ATPase subunit H is essential for the survival and moulting of Locusta migratoria manilensis
Q38394728Vacuolar H(+)-ATPase subunits Voa1 and Voa2 cooperatively regulate secretory vesicle acidification, transmitter uptake, and storage
Q38317885Vacuolar H+ ATPase expression and activity is required for Rab27B-dependent invasive growth and metastasis of breast cancer
Q92690192Vacuolar-type ATPase: A proton pump to lysosomal trafficking
Q96302347Widely available lysosome targeting agents should be considered as a potential therapy for COVID-19
Q47428579Zinc transporter 2 interacts with vacuolar ATPase and is required for polarization, vesicle acidification, and secretion in mammary epithelial cells
Q52714767ZnT2 is critical for lysosome acidification and biogenesis during mammary gland involution.
Q43099218{alpha}MSH and Cyclic AMP elevating agents control melanosome pH through a protein kinase A-independent mechanism.

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