Identification of the Cdc48•20S proteasome as an ancient AAA+ proteolytic machine.

scientific article published on 26 July 2012

Identification of the Cdc48•20S proteasome as an ancient AAA+ proteolytic machine. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1126/SCIENCE.1224352
P932PMC publication ID3923512
P698PubMed publication ID22837385
P5875ResearchGate publication ID230573957

P50authorRobert T SauerQ67918080
P2093author name stringDominik Barthelme
P2860cites workCoupled assay of Na+,K+-ATPase activityQ69826419
Critical elements in proteasome assemblyQ71955022
PAN, the proteasome-activating nucleotidase from archaebacteria, is a protein-unfolding molecular chaperoneQ73135763
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational changeQ27650550
Structural Insights into the Regulatory Particle of the Proteasome from Methanocaldococcus jannaschiiQ27655690
Structural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsQ27658058
Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMRQ27660397
A novel ATP-dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease-related mutantsQ27662051
Complete subunit architecture of the proteasome regulatory particleQ28257212
Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin systemQ28258706
The 26S proteasome: a molecular machine designed for controlled proteolysisQ29619692
An archaebacterial ATPase, homologous to ATPases in the eukaryotic 26 S proteasome, activates protein breakdown by 20 S proteasomesQ33873082
ATP binding to PAN or the 26S ATPases causes association with the 20S proteasome, gate opening, and translocation of unfolded proteins.Q33991996
AAA+ proteases: ATP-fueled machines of protein destructionQ34176192
Proteasome activatorsQ37826501
Cdc48: a power machine in protein degradationQ37899368
Proteasomal components required for cell growth and stress responses in the haloarchaeon Haloferax volcaniiQ41367038
The role of the N-domain in the ATPase activity of the mammalian AAA ATPase p97/VCP.Q42558471
Linkage between ATP consumption and mechanical unfolding during the protein processing reactions of an AAA+ degradation machine.Q44563531
VAT, the thermoplasma homolog of mammalian p97/VCP, is an N domain-regulated protein unfoldaseQ46763702
Protein unfolding by a AAA+ protease is dependent on ATP-hydrolysis rates and substrate energy landscapes.Q46788602
A malachite green procedure for orthophosphate determination and its use in alkaline phosphatase-based enzyme immunoassay.Q50896016
P433issue6096
P407language of work or nameEnglishQ1860
P921main subjectproteolysisQ33123
P304page(s)843-846
P577publication date2012-07-26
P1433published inScienceQ192864
P1476titleIdentification of the Cdc48•20S proteasome as an ancient AAA+ proteolytic machine
P478volume337

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cites work (P2860)
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