A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding

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A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding is …
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scholarly articleQ13442814

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P356DOI10.1038/NSMB.2027
P932PMC publication ID3087856
P698PubMed publication ID21499243
P5875ResearchGate publication ID51057092

P50authorMark HochstrasserQ28320733
P2093author name stringMary J Kunjappu
Andrew R Kusmierczyk
Roger Y Kim
P2860cites workComplete Genome Sequence of the Genetically Tractable Hydrogenotrophic Methanogen Methanococcus maripaludisQ22065454
cDNA cloning, expression, and functional characterization of PI31, a proline-rich inhibitor of the proteasomeQ22253889
A heterodimeric complex that promotes the assembly of mammalian 20S proteasomesQ24292874
Assembly pathway of the Mammalian proteasome base subcomplex is mediated by multiple specific chaperonesQ24316277
Chaperone-mediated pathway of proteasome regulatory particle assemblyQ24321620
Mechanism of gate opening in the 20S proteasome by the proteasomal ATPasesQ24564109
Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entryQ24674433
A gated channel into the proteasome core particleQ27627907
Structural basis for the activation of 20S proteasomes by 11S regulatorsQ27628418
Investigations on the maturation and regulation of archaebacterial proteasomesQ27640607
Crystal structure of a chaperone complex that contributes to the assembly of yeast 20S proteasomesQ27649865
Structural Models for Interactions between the 20S Proteasome and Its PAN/19S ActivatorsQ27658058
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolutionQ27730197
Structure of 20S proteasome from yeast at 2.4 A resolutionQ27735081
Blm3 is part of nascent proteasomes and is involved in a late stage of nuclear proteasome assemblyQ27930761
The C-terminal extension of the beta7 subunit and activator complexes stabilize nascent 20 S proteasomes and promote their maturationQ27930979
Proteasomal proteomics: identification of nucleotide-sensitive proteasome-interacting proteins by mass spectrometric analysis of affinity-purified proteasomesQ27931576
Autocatalytic subunit processing couples active site formation in the 20S proteasome to completion of assemblyQ27931608
RPN4 is a ligand, substrate, and transcriptional regulator of the 26S proteasome: a negative feedback circuitQ27933746
A multimeric assembly factor controls the formation of alternative 20S proteasomesQ27933912
beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpointQ27935938
20S proteasome assembly is orchestrated by two distinct pairs of chaperones in yeast and in mammals.Q27936515
Multiple proteasome-interacting proteins assist the assembly of the yeast 19S regulatory particleQ27936642
The HEAT repeat protein Blm10 regulates the yeast proteasome by capping the core particleQ27938094
Hsm3/S5b participates in the assembly pathway of the 19S regulatory particle of the proteasomeQ27938858
Multiple assembly chaperones govern biogenesis of the proteasome regulatory particle baseQ27939675
Differential roles of the COOH termini of AAA subunits of PA700 (19 S regulator) in asymmetric assembly and activation of the 26 S proteasomeQ28294192
Unraveling the biochemistry and provenance of pupylation: a prokaryotic analog of ubiquitinationQ33382260
The 1.9 A structure of a proteasome-11S activator complex and implications for proteasome-PAN/PA700 interactions.Q33987362
Molecular mechanisms of proteasome assemblyQ34928594
The proteasome: overview of structure and functionsQ36472495
Proteasomes from structure to function: perspectives from ArchaeaQ36597934
Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesisQ37116375
PACemakers of proteasome core particle assembly.Q37266780
Biogenesis, structure and function of the yeast 20S proteasomeQ40806956
The proteasome inhibitor PI31 competes with PA28 for binding to 20S proteasomes.Q40931474
A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channelQ42177637
Nanoenzymology of the 20S proteasome: proteasomal actions are controlled by the allosteric transitionQ42677060
Stability of the proteasome can be regulated allosterically through engagement of its proteolytic active sites.Q46891027
Atomic force microscopy reveals two conformations of the 20 S proteasome from fission yeastQ57752879
Mass Spectrometry Reveals the Missing Links in the Assembly Pathway of the Bacterial 20 S ProteasomeQ63229606
Critical elements in proteasome assemblyQ71955022
P433issue5
P304page(s)622-629
P577publication date2011-04-17
P1433published inNature Structural & Molecular BiologyQ1071739
P1476titleA conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor binding
P478volume18

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cites work (P2860)
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Q34137316Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors

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