Distinct Elements in the Proteasomal β5 Subunit Propeptide Required for Autocatalytic Processing and Proteasome Assembly

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Distinct Elements in the Proteasomal β5 Subunit Propeptide Required for Autocatalytic Processing and Proteasome Assembly is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M115.677047
P932PMC publication ID4722473
P698PubMed publication ID26627836

P50authorMark HochstrasserQ28320733
P2093author name stringXia Li
Yanjie Li
Cassandra S Arendt
P2860cites workIFN-gamma-induced immune adaptation of the proteasome system is an accelerated and transient responseQ24531439
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beta-Subunit appendages promote 20S proteasome assembly by overcoming an Ump1-dependent checkpointQ27935938
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Protein degradation and the generation of MHC class I-presented peptides.Q34700398
A conserved 20S proteasome assembly factor requires a C-terminal HbYX motif for proteasomal precursor bindingQ34928089
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Maturation of the proteasome core particle induces an affinity switch that controls regulatory particle associationQ35234644
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Dissecting beta-ring assembly pathway of the mammalian 20S proteasome.Q36844289
eIF5A promotes translation of polyproline motifs.Q37098599
Some assembly required: dedicated chaperones in eukaryotic proteasome biogenesisQ37116375
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Degradation of centromeric histone H3 variant Cse4 requires the Fpr3 peptidyl-prolyl Cis-Trans isomeraseQ37696375
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Structural biology of the proteasomeQ38081952
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Assembly mechanisms of specialized core particles of the proteasomeQ38888348
The eIF-2 alpha kinases: regulators of protein synthesis in starvation and stressQ40503407
Biogenesis, structure and function of the yeast 20S proteasomeQ40806956
Genes encoded in the major histocompatibility complex affecting the generation of peptides for TAP transportQ41371575
20 S proteasomes are assembled via distinct precursor complexes. Processing of LMP2 and LMP7 proproteins takes place in 13-16 S preproteasome complexesQ41481469
Proteasomes: Isolation and Activity Assays.Q41623176
Eukaryotic 20S proteasome catalytic subunit propeptides prevent active site inactivation by N-terminal acetylation and promote particle assemblyQ42147758
Chaperone-assisted assembly of the proteasome core particleQ47838223
Conformational constraints for protein self-cleavage in the proteasomeQ47923187
PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chrymotryptic activity and degradation of ubiquitinated proteinsQ48129568
Basic Medical Research Award. The ubiquitin systemQ48372080
Proteasome β-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site functionQ60656421
Novel propeptide function in 20 S proteasome assembly influences beta subunit compositionQ73804905
Two-stage polymerase chain reaction protocol allowing introduction of multiple mutations, deletions, and insertions, using QuikChange site-directed mutagenesisQ77426888
Proteasome assembly from 15S precursors involves major conformational changes and recycling of the Pba1-Pba2 chaperoneQ86573364
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectautocatalysisQ786897
P304page(s)1991-2003
P577publication date2015-12-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleDistinct Elements in the Proteasomal β5 Subunit Propeptide Required for Autocatalytic Processing and Proteasome Assembly
P478volume291

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cites work (P2860)
Q36690211A unified mechanism for proteolysis and autocatalytic activation in the 20S proteasome.
Q94540572Cooperativity in Proteasome Core Particle Maturation
Q92972669Dynamic Regulation of the 26S Proteasome: From Synthesis to Degradation
Q39352782Proteasome Structure and Assembly
Q38966261Proteasome dynamics between proliferation and quiescence stages of Saccharomyces cerevisiae.
Q64092688Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster
Q90673658Regulation of proteasome assembly and activity in health and disease

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