| scholarly article | Q13442814 |
| P50 | author | Jim Karagiannis | Q55807641 |
| Gregory B. Gloor | Q37834895 | ||
| P2093 | author name string | Christopher J Brandl | |
| Julie Genereaux | |||
| Megan J Davey | |||
| Lance F DaSilva | |||
| Samantha Pillon | |||
| P2860 | cites work | Ultrafast and memory-efficient alignment of short DNA sequences to the human genome | Q21183894 |
| The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells | Q24294881 | ||
| Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes | Q24297874 | ||
| A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability | Q24298271 | ||
| CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability | Q24300796 | ||
| Tel2 regulates the stability of PI3K-related protein kinases | Q24304948 | ||
| The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteins | Q24328753 | ||
| ATRIP binding to replication protein A-single-stranded DNA promotes ATR-ATRIP localization but is dispensable for Chk1 phosphorylation | Q24523440 | ||
| Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases | Q24564109 | ||
| Minichromosome maintenance proteins are direct targets of the ATM and ATR checkpoint kinases | Q24564474 | ||
| MUSCLE: multiple sequence alignment with high accuracy and high throughput | Q24613456 | ||
| Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly | Q24632884 | ||
| Emerging common themes in regulation of PIKKs and PI3Ks | Q24647293 | ||
| Common mechanisms of PIKK regulation | Q24653672 | ||
| Yeast counterparts of subunits S5a and p58 (S3) of the human 26S proteasome are encoded by two multicopy suppressors of nin1-1 | Q24654196 | ||
| Docking of the proteasomal ATPases' carboxyl termini in the 20S proteasome's alpha ring opens the gate for substrate entry | Q24674433 | ||
| Proteasome subunit Rpn13 is a novel ubiquitin receptor | Q27650664 | ||
| Ubiquitin docking at the proteasome through a novel pleckstrin-homology domain interaction | Q27650666 | ||
| Global analysis of protein localization in budding yeast | Q27653962 | ||
| Crystal structure of DNA-PKcs reveals a large open-ring cradle comprised of HEAT repeats | Q27658689 | ||
| mTOR kinase structure, mechanism and regulation | Q27677954 | ||
| Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes | Q27860662 | ||
| The Sequence Alignment/Map format and SAMtools | Q27860966 | ||
| The multiubiquitin-chain-binding protein Mcb1 is a component of the 26S proteasome in Saccharomyces cerevisiae and plays a nonessential, substrate-specific role in protein turnover. | Q27929822 | ||
| Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1. | Q27930623 | ||
| Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase | Q27930725 | ||
| Recruitment of a 19S proteasome subcomplex to an activated promoter | Q43966343 | ||
| Alterations in a yeast protein resembling HIV Tat-binding protein relieve requirement for an acidic activation domain in GAL4. | Q44211063 | ||
| Degradation of ornithine decarboxylase in reticulocyte lysate is ATP-dependent but ubiquitin-independent | Q44617013 | ||
| The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability | Q46384104 | ||
| Isolation and characterization of SUG2. A novel ATPase family component of the yeast 26 S proteasome | Q48056605 | ||
| Activation of the checkpoint kinase Rad53 by the phosphatidyl inositol kinase-like kinase Mec1. | Q53643560 | ||
| Saccharomyces cerevisiae Rad9 acts as a Mec1 adaptor to allow Rad53 activation. | Q53662825 | ||
| The ATRs, ATMs, and TORs are giant HEAT repeat proteins. | Q55036334 | ||
| FAT: a novel domain in PIK-related kinases | Q57444244 | ||
| Structural insights into phosphoinositide 3-kinase catalysis and signalling | Q57648104 | ||
| Functional analysis of the yeast genome | Q59546362 | ||
| The 19S Regulatory Complex of the Proteasome Functions Independently of Proteolysis in Nucleotide Excision Repair | Q63383896 | ||
| Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2 | Q73084666 | ||
| Proteasome inhibition in wild-type yeast Saccharomyces cerevisiae cells | Q79991414 | ||
| HSP90 and the R2TP co-chaperone complex: building multi-protein machineries essential for cell growth and gene expression | Q83653688 | ||
| A role for Saccharomyces cerevisiae histone H2A in DNA repair. | Q27930827 | ||
| Recruitment of HAT complexes by direct activator interactions with the ATM-related Tra1 subunit | Q27933602 | ||
| The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast | Q27934134 | ||
| Functional characterization of rpn3 uncovers a distinct 19S proteasomal subunit requirement for ubiquitin-dependent proteolysis of cell cycle regulatory proteins in budding yeast | Q27934456 | ||
| In vivo target of a transcriptional activator revealed by fluorescence resonance energy transfer | Q27935003 | ||
| The DNA replication and damage checkpoint pathways induce transcription by inhibition of the Crt1 repressor | Q27935222 | ||
| Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair | Q27935229 | ||
| The proteasome regulatory particle alters the SAGA coactivator to enhance its interactions with transcriptional activators. | Q27935912 | ||
| Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo | Q27937212 | ||
| The ATM-related cofactor Tra1 is a component of the purified SAGA complex | Q27937594 | ||
| Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome | Q27937927 | ||
| The 19S complex of the proteasome regulates nucleotide excision repair in yeast. | Q27937965 | ||
| A suppressor of two essential checkpoint genes identifies a novel protein that negatively affects dNTP pools | Q27938474 | ||
| Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway | Q27938580 | ||
| S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex | Q27938718 | ||
| LCD1: an essential gene involved in checkpoint control and regulation of the MEC1 signalling pathway in Saccharomyces cerevisiae | Q27938784 | ||
| Mec1/Tel1 phosphorylation of the INO80 chromatin remodeling complex influences DNA damage checkpoint responses | Q27939218 | ||
| The 19S regulatory particle of the proteasome is required for efficient transcription elongation by RNA polymerase II. | Q27939755 | ||
| Tra1p is a component of the yeast Ada.Spt transcriptional regulatory complexes. | Q27939931 | ||
| Telomeric repeat containing RNA and RNA surveillance factors at mammalian chromosome ends | Q28116571 | ||
| Carboxyl-terminal region conserved among phosphoinositide-kinase-related kinases is indispensable for mTOR function in vivo and in vitro | Q28145271 | ||
| Complete subunit architecture of the proteasome regulatory particle | Q28257212 | ||
| Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach | Q28259014 | ||
| Distant N- and C-terminal domains are required for intrinsic kinase activity of SMG-1, a critical component of nonsense-mediated mRNA decay | Q28283771 | ||
| The nonsense-mediated decay RNA surveillance pathway | Q28292588 | ||
| Recognition and processing of ubiquitin-protein conjugates by the proteasome | Q29547616 | ||
| ATR: an essential regulator of genome integrity | Q29547883 | ||
| Conserved modes of recruitment of ATM, ATR and DNA-PKcs to sites of DNA damage | Q29614218 | ||
| Activating mutations in TOR are in similar structures as oncogenic mutations in PI3KCalpha | Q30437618 | ||
| Near-atomic resolution structural model of the yeast 26S proteasome. | Q30524942 | ||
| Molecular and biochemical characterisation of DNA-dependent protein kinase-defective rodent mutant irs-20 | Q32082716 | ||
| Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations | Q33229596 | ||
| Proteasomal turnover of p21Cip1 does not require p21Cip1 ubiquitination | Q33908311 | ||
| Function of a eukaryotic transcription activator during the transcription cycle | Q34415384 | ||
| Targets of the Gal4 transcription activator in functional transcription complexes. | Q34456105 | ||
| The base of the proteasome regulatory particle exhibits chaperone-like activity | Q34505766 | ||
| DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1. | Q35561531 | ||
| Target of rapamycin (TOR) in nutrient signaling and growth control | Q35620394 | ||
| The 19S proteasome subcomplex promotes the targeting of NuA4 HAT to the promoters of ribosomal protein genes to facilitate the recruitment of TFIID for transcriptional initiation in vivo | Q35823742 | ||
| PI 3-kinase related kinases: 'big' players in stress-induced signaling pathways | Q35848445 | ||
| Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. | Q35966662 | ||
| Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1. | Q36076885 | ||
| Sug1 modulates yeast transcription activation by Cdc68. | Q36555713 | ||
| TopBP1 activates ATR through ATRIP and a PIKK regulatory domain | Q36706894 | ||
| The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast | Q36840988 | ||
| hSMG-1 and ATM sequentially and independently regulate the G1 checkpoint during oxidative stress | Q37118988 | ||
| Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination | Q37142785 | ||
| ATR/Mec1: coordinating fork stability and repair. | Q37397197 | ||
| DNA replication as a target of the DNA damage checkpoint | Q37511322 | ||
| TOR complex 2: a signaling pathway of its own. | Q37624179 | ||
| 4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase | Q37628904 | ||
| The role of Hsp90 in protein complex assembly | Q37938261 | ||
| Surviving chromosome replication: the many roles of the S-phase checkpoint pathway | Q37956284 | ||
| Structural biology of the proteasome | Q38081952 | ||
| The C-terminal conserved domain of DNA-PKcs, missing in the SCID mouse, is required for kinase activity | Q38314660 | ||
| Mcm2 is a direct substrate of ATM and ATR during DNA damage and DNA replication checkpoint responses | Q38336111 | ||
| BCR-ABL prevents c-jun-mediated and proteasome-dependent FUS (TLS) proteolysis through a protein kinase CbetaII-dependent pathway | Q39454928 | ||
| Pie1, a protein interacting with Mec1, controls cell growth and checkpoint responses in Saccharomyces cerevisiae | Q39457690 | ||
| Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast. | Q39605118 | ||
| Mec1 function in the DNA damage response does not require its interaction with Tel2 | Q39656675 | ||
| Tel1(ATM) and Rad3(ATR) phosphorylate the telomere protein Ccq1 to recruit telomerase and elongate telomeres in fission yeast. | Q39754561 | ||
| MDM2 promotes proteasome-dependent ubiquitin-independent degradation of retinoblastoma protein. | Q40342115 | ||
| Heterohexameric ring arrangement of the eukaryotic proteasomal ATPases: implications for proteasome structure and assembly. | Q40836221 | ||
| Structure/function analysis of the phosphatidylinositol-3-kinase domain of yeast tra1. | Q41580909 | ||
| Domains of Tra1 important for activator recruitment and transcription coactivator functions of SAGA and NuA4 complexes. | Q42141775 | ||
| Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. | Q42687620 | ||
| PHAS-I as a link between mitogen-activated protein kinase and translation initiation | Q42833060 | ||
| Fission yeast Ccq1 is telomerase recruiter and local checkpoint controller. | Q43223959 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| ImageQuant | Q112270642 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Saccharomyces cerevisiae | Q719725 |
| Protein kinase MEC1 YBR136W | Q27548640 | ||
| P304 | page(s) | 1661-74 | |
| P577 | publication date | 2013-10-03 | |
| P1433 | published in | G3 | Q5512701 |
| P1476 | title | The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function | |
| P478 | volume | 3 |
| Q26747245 | ATR-mediated regulation of nuclear and cellular plasticity |
| Q27933225 | Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response |
| Q52329552 | The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes. |
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