Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2

scientific article published on 01 February 1997

Identification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2 is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1074/JBC.272.9.5571
P698PubMed publication ID9038164

P50authorAyman M SalehQ46640792
P2093author name stringR Cook
V Lang
C J Brandl
P2860cites workIdentification of human proteins functionally conserved with the yeast putative adaptors ADA2 and GCN5Q24315711
Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition methodQ24631695
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Isolation of monoclonal antibodies specific for human c-myc proto-oncogene productQ27860841
ADA3, a putative transcriptional adaptor, consists of two separable domains and interacts with ADA2 and GCN5 in a trimeric complexQ27930121
ADA5/SPT20 links the ADA and SPT genes, which are involved in yeast transcriptionQ27932447
TFIIF-TAF-RNA polymerase II connectionQ27932651
SSN genes that affect transcriptional repression in Saccharomyces cerevisiae encode SIN4, ROX3, and SRB proteins associated with RNA polymerase IIQ27933314
Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of yeastQ27933378
Yeast ADA2 protein binds to the VP16 protein activation domain and activates transcription.Q27935228
RNA polymerase II subunit RPB3 is an essential component of the mRNA transcription apparatusQ27936059
SNF11, a new component of the yeast SNF-SWI complex that interacts with a conserved region of SNF2.Q27937070
Tetrahymena histone acetyltransferase A: a homolog to yeast Gcn5p linking histone acetylation to gene activationQ27937778
New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sitesQ28131597
A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistanceQ28131606
Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domainsQ29620928
The RNA polymerase II holoenzyme and its implications for gene regulationQ29622942
Saturation mutagenesis of a yeast his3 "TATA element": genetic evidence for a specific TATA-binding proteinQ33567358
Yeast global transcriptional regulators Sin4 and Rgr1 are components of mediator complex/RNA polymerase II holoenzyme.Q33739221
Mutations in RNA polymerase II enhance or suppress mutations in GAL4.Q33850755
Identification and characterization of a TFIID-like multiprotein complex from Saccharomyces cerevisiaeQ33958879
GAL4 interacts with TATA-binding protein and coactivatorsQ34309986
Paf1p, an RNA polymerase II-associated factor in Saccharomyces cerevisiae, may have both positive and negative roles in transcriptionQ36557179
Analysis of Saccharomyces cerevisiae his3 transcription in vitro: biochemical support for multiple mechanisms of transcriptionQ36710678
ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.Q36822602
Specific initiation by RNA polymerase I in a whole-cell extract from yeastQ37391358
Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeastQ37539289
Structural and functional analysis of yeast putative adaptors. Evidence for an adaptor complex in vivoQ38361167
SPT20/ADA5 encodes a novel protein functionally related to the TATA-binding protein and important for transcription in Saccharomyces cerevisiaeQ40019111
Common themes in assembly and function of eukaryotic transcription complexesQ40422045
The SNF/SWI family of global transcriptional activatorsQ40626454
TBP-TAF complexes: selectivity factors for eukaryotic transcriptionQ40626459
Transcriptional activation by yeast PDR1p is inhibited by its association with NGG1p/ADA3pQ48062271
Genetic evidence for the interaction of the yeast transcriptional co-activator proteins GCN5 and ADA2.Q52511808
Structure/functional properties of the yeast dual regulator protein NGG1 that are required for glucose repression.Q52519385
Yeast TAFIIS in a multisubunit complex required for activated transcription.Q52541518
Characterization of Physical Interactions of the Putative Transcriptional Adaptor, ADA2, with Acidic Activation Domains and TATA-binding ProteinQ58130306
DNA-binding properties of the yeast SWI/SNF complexQ59068266
RNA polymerase II holoenzyme contains SWI/SNF regulators involved in chromatin remodelingQ70908581
P433issue9
P407language of work or nameEnglishQ1860
P304page(s)5571-5578
P577publication date1997-02-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleIdentification of native complexes containing the yeast coactivator/repressor proteins NGG1/ADA3 and ADA2
P478volume272

Reverse relations

cites work (P2860)
Q41653844A SAGA of histone acetylation and gene expression
Q22011164A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth
Q24682174A novel human Ada2 homologue functions with Gcn5 or Brg1 to coactivate transcription
Q27936635A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation
Q24650997A systematic screen for transcriptional regulators of the yeast cell cycle
Q27939725ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3.
Q24530010ADA3-containing complexes associate with estrogen receptor alpha
Q60909339Acceptor Stem Differences Contribute to Species-Specific Use of Yeast and Human tRNA
Q24548503Acetylation of histones and transcription-related factors
Q27934769Analysis of Spt7 function in the Saccharomyces cerevisiae SAGA coactivator complex.
Q33293626C-terminal processing of yeast Spt7 occurs in the absence of functional SAGA complex
Q30448772Cell cycle-regulated histone acetylation required for expression of the yeast HO gene
Q36416226Characterization of new Spt3 and TATA-binding protein mutants of Saccharomyces cerevisiae: Spt3 TBP allele-specific interactions and bypass of Spt8.
Q24798328Characterization of yeast histone H3-specific type B histone acetyltransferases identifies an ADA2-independent Gcn5p activity
Q35748234Chromatin and transcription in yeast
Q77570570Chromatin remodeling: a marriage between two families?
Q27937089Cluster analysis of mass spectrometry data reveals a novel component of SAGA
Q27932566Combinatorial depletion analysis to assemble the network architecture of the SAGA and ADA chromatin remodeling complexes
Q34281088Components of the SAGA histone acetyltransferase complex are required for repressed transcription of ARG1 in rich medium
Q33847058Contribution of CgPDR1-regulated genes in enhanced virulence of azole-resistant Candida glabrata
Q35193069Critical residues for histone acetylation by Gcn5, functioning in Ada and SAGA complexes, are also required for transcriptional function in vivo
Q28575519Deregulated expression of a novel component of TFTC/STAGA histone acetyltransferase complexes, rat SGF29, in hepatocellular carcinoma: possible implication for the oncogenic potential of c-Myc
Q33970848Essential functional interactions of SAGA, a Saccharomyces cerevisiae complex of Spt, Ada, and Gcn5 proteins, with the Snf/Swi and Srb/mediator complexes
Q27930736Functional organization of the yeast SAGA complex: distinct components involved in structural integrity, nucleosome acetylation, and TATA-binding protein interaction.
Q33529002GCN5 is a positive regulator of origins of DNA replication in Saccharomyces cerevisiae
Q43977755Gal80 confers specificity on HAT complex interactions with activators
Q27929940Histone H3 specific acetyltransferases are essential for cell cycle progression
Q35192911Histone acetyltransferase activity of yeast Gcn5p is required for the activation of target genes in vivo
Q33959141Histone acetyltransferase complexes can mediate transcriptional activation by the major glucocorticoid receptor activation domain
Q28202210Human papilloma virus 16 E6 oncoprotein inhibits retinoic X receptor-mediated transactivation by targeting human ADA3 coactivator
Q24537722Human papillomavirus oncoprotein E6 inactivates the transcriptional coactivator human ADA3
Q44900828Identification and analysis of native HAT complexes.
Q27931284Identification of two novel TAF subunits of the yeast Saccharomyces cerevisiae TFIID complex
Q27938704Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters
Q27939381Interdependent recruitment of SAGA and Srb mediator by transcriptional activator Gcn4p
Q36216047Mammalian alteration/deficiency in activation 3 (Ada3) is essential for embryonic development and cell cycle progression
Q29620260Molecular genetics of the RNA polymerase II general transcriptional machinery
Q27930623Mutational analysis of the C-terminal FATC domain of Saccharomyces cerevisiae Tra1.
Q42664605Mutations in both the structured domain and N-terminus of histone H2B bypass the requirement for Swi-Snf in yeast
Q36155203Nucleosome competition reveals processive acetylation by the SAGA HAT module.
Q42002467Nucleosome structure of the yeast CHA1 promoter: analysis of activation-dependent chromatin remodeling of an RNA-polymerase-II-transcribed gene in TBP and RNA pol II mutants defective in vivo in response to acidic activators.
Q33911284Phosphorylation of serine 10 in histone H3 is functionally linked in vitro and in vivo to Gcn5-mediated acetylation at lysine 14.
Q27933987Positive and negative functions of the SAGA complex mediated through interaction of Spt8 with TBP and the N-terminal domain of TFIIA.
Q27931371Proteomics of the eukaryotic transcription machinery: identification of proteins associated with components of yeast TFIID by multidimensional mass spectrometry
Q35206109Recruitment of the SWI/SNF chromatin remodeling complex by transcriptional activators
Q40023668Role for ADA/GCN5 products in antagonizing chromatin-mediated transcriptional repression
Q27937005Rpm2p, a component of yeast mitochondrial RNase P, acts as a transcriptional activator in the nucleus
Q27936016SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription
Q39452532SWI-SNF-mediated nucleosome remodeling: role of histone octamer mobility in the persistence of the remodeled state
Q41580909Structure/function analysis of the phosphatidylinositol-3-kinase domain of yeast tra1.
Q27932073Systematic genetic array analysis links the Saccharomyces cerevisiae SAGA/SLIK and NuA4 component Tra1 to multiple cellular processes
Q27931014The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae
Q27937594The ATM-related cofactor Tra1 is a component of the purified SAGA complex
Q27937771The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function
Q41077086The Drosophila histone acetyltransferase Gcn5 and transcriptional adaptor Ada2a are involved in nucleosomal histone H4 acetylation
Q33772811The Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex
Q28513184The PCAF acetylase complex as a potential tumor suppressor
Q35070043The PS1 hairpin of Mcm3 is essential for viability and for DNA unwinding in vitro
Q52329552The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes.
Q42459431The SAGA unfolds: convergence of transcription regulators in chromatin-modifying complexes.
Q24554343The essential cofactor TRRAP recruits the histone acetyltransferase hGCN5 to c-Myc
Q27934606The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.
Q27930726The something about silencing protein, Sas3, is the catalytic subunit of NuA3, a yTAF(II)30-containing HAT complex that interacts with the Spt16 subunit of the yeast CP (Cdc68/Pob3)-FACT complex
Q35199113The yeast Ada complex mediates the ligand-dependent activation function AF-2 of retinoid X and estrogen receptors
Q73821749The yeast histone acetyltransferase A2 complex, but not free Gcn5p, binds stably to nucleosomal arrays
Q27936339Transcriptional activation by Gcn4p involves independent interactions with the SWI/SNF complex and the SRB/mediator
Q89709144Whitefly HES1 binds to the intergenic region of Tomato yellow leaf curl China virus and promotes viral gene transcription
Q29622932Yeast carbon catabolite repression
Q27940108Yeast enhancer of polycomb defines global Esa1-dependent acetylation of chromatin.
Q27935097Yng1p modulates the activity of Sas3p as a component of the yeast NuA3 Hhistone acetyltransferase complex
Q77652532yTAFII61 has a general role in RNA polymerase II transcription and is required by Gcn4p to recruit the SAGA coactivator complex

Search more.