Architecture of human translation initiation factor 3.

scientific article published on 25 April 2013

Architecture of human translation initiation factor 3. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.STR.2013.04.002
P932PMC publication ID3739965
P698PubMed publication ID23623729
P5875ResearchGate publication ID236458935

P50authorEva NogalesQ4795157
Jamie H. D. CateQ87623216
P2093author name stringYu Gu
Chaomin Sun
Jacob M Vogan
M Duane Smith
Jordi Querol-Audi
P2860cites workThe j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitroQ24302384
The crystal structure of the human Mov34 MPN domain reveals a metal-free dimerQ24309182
Mass spectrometry reveals modularity and a complete subunit interaction map of the eukaryotic translation factor eIF3Q24309617
Domains of eIF1A that mediate binding to eIF2, eIF3 and eIF5B and promote ternary complex recruitment in vivoQ24540322
Functional elements in initiation factors 1, 1A, and 2β discriminate against poor AUG context and non-AUG start codonsQ24631083
Prediction of a common structural scaffold for proteasome lid, COP9-signalosome and eIF3 complexesQ24811581
Specific interaction of eukaryotic translation initiation factor 3 with the 5' nontranslated regions of hepatitis C virus and classical swine fever virus RNAsQ27469565
Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunitQ27643432
Crystal structure of the eukaryotic 40S ribosomal subunit in complex with initiation factor 1Q27666453
The structure of the eukaryotic ribosome at 3.0 Å resolutionQ27675638
The proteasomal subunit Rpn6 is a molecular clamp holding the core and regulatory subcomplexes togetherQ27676340
The crystal structure of the MPN domain from the COP9 signalosome subunit CSN6Q27679008
Protein structure prediction on the Web: a case study using the Phyre serverQ27860664
EMAN: semiautomated software for high-resolution single-particle reconstructionsQ27860772
EMAN2: an extensible image processing suite for electron microscopyQ27861052
A multifactor complex of eukaryotic initiation factors, eIF1, eIF2, eIF3, eIF5, and initiator tRNA(Met) is an important translation initiation intermediate in vivoQ27876228
A conformational change in the eukaryotic translation preinitiation complex and release of eIF1 signal recognition of the start codonQ27932344
Related eIF3 subunits TIF32 and HCR1 interact with an RNA recognition motif in PRT1 required for eIF3 integrity and ribosome bindingQ27933942
The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosomeQ27934357
A new generation of the IMAGIC image processing systemQ28131751
Changes in integrity and association of eukaryotic protein synthesis initiation factors during apoptosisQ28144595
Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3Q28205873
Complete subunit architecture of the proteasome regulatory particleQ28257212
Molecular architecture of the 26S proteasome holocomplex determined by an integrative approachQ28259014
Crystal structure of human eIF3k, the first structure of eIF3 subunitsQ28265251
Appion: an integrated, database-driven pipeline to facilitate EM image processingQ29614288
Automated molecular microscopy: the new Leginon systemQ29614290
The roles of individual eukaryotic translation initiation factors in ribosomal scanning and initiation codon selectionQ33962536
The indispensable N-terminal half of eIF3j/HCR1 cooperates with its structurally conserved binding partner eIF3b/PRT1-RRM and with eIF1A in stringent AUG selectionQ34091806
The C-terminal region of eukaryotic translation initiation factor 3a (eIF3a) promotes mRNA recruitment, scanning, and, together with eIF3j and the eIF3b RNA recognition motif, selection of AUG start codons.Q34119657
Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3).Q34237617
Distinct regions of human eIF3 are sufficient for binding to the HCV IRES and the 40S ribosomal subunitQ34284595
The mechanism of eukaryotic translation initiation: new insights and challengesQ34289214
Small ribosomal protein RPS0 stimulates translation initiation by mediating 40S-binding of eIF3 via its direct contact with the eIF3a/TIF32 subunitQ34336340
Structural roles for human translation factor eIF3 in initiation of protein synthesisQ34472092
Release of initiation factors from 48S complexes during ribosomal subunit joining and the link between establishment of codon-anticodon base-pairing and hydrolysis of eIF2-bound GTP.Q34553474
Interaction of the RNP1 motif in PRT1 with HCR1 promotes 40S binding of eukaryotic initiation factor 3 in yeastQ34563179
Structural and mechanistic insights into hepatitis C viral translation initiationQ34584874
eIF3j is located in the decoding center of the human 40S ribosomal subunitQ34641203
Recycling of eukaryotic posttermination ribosomal complexesQ34705837
The human translation initiation multi-factor complex promotes methionyl-tRNAi binding to the 40S ribosomal subunitQ35672266
eIF3a cooperates with sequences 5' of uORF1 to promote resumption of scanning by post-termination ribosomes for reinitiation on GCN4 mRNA.Q36869067
Structural basis for a reciprocal regulation between SCF and CSN.Q36988986
Position of eukaryotic translation initiation factor eIF1A on the 40S ribosomal subunit mapped by directed hydroxyl radical probing.Q37318477
Interactions of eukaryotic translation initiation factor 3 (eIF3) subunit NIP1/c with eIF1 and eIF5 promote preinitiation complex assembly and regulate start codon selectionQ37574552
PCI complexes: Beyond the proteasome, CSN, and eIF3 Troika.Q37580456
Translational control in cancer.Q37717999
Molecular model of the human 26S proteasomeQ41613713
Functional characterization of the role of the N-terminal domain of the c/Nip1 subunit of eukaryotic initiation factor 3 (eIF3) in AUG recognition.Q41974670
Structural insights into the COP9 signalosome and its common architecture with the 26S proteasome lid and eIF3.Q42152342
Pi release from eIF2, not GTP hydrolysis, is the step controlled by start-site selection during eukaryotic translation initiationQ46772123
The PCI domain: a common theme in three multiprotein complexesQ47916829
P433issue6
P304page(s)920-928
P577publication date2013-04-25
P1433published inStructureQ15709970
P1476titleArchitecture of human translation initiation factor 3.
P478volume21

Reverse relations

cites work (P2860)
Q41698817A Transcript-Specific eIF3 Complex Mediates Global Translational Control of Energy Metabolism
Q92167429Adapted formaldehyde gradient cross-linking protocol implicates human eIF3d and eIF3c, k and l subunits in the 43S and 48S pre-initiation complex assembly, respectively
Q24701801An RNA trapping mechanism in Alphavirus mRNA promotes ribosome stalling and translation initiation
Q37078817Assembly of eIF3 Mediated by Mutually Dependent Subunit Insertion
Q37729759Coupling 40S ribosome recruitment to modification of a cap-binding initiation factor by eIF3 subunit e.
Q27694578Crystal structure of the human COP9 signalosome
Q27681666Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11
Q47234689Embraced by eIF3: structural and functional insights into the roles of eIF3 across the translation cycle.
Q89729270Engineered transient and stable overexpression of translation factors eIF3i and eIF3c in CHOK1 and HEK293 cells gives enhanced cell growth associated with increased c-Myc expression and increased recombinant protein synthesis
Q37635646Eukaryotic translation initiation factor 3 subunit D overexpression is associated with the occurrence and development of ovarian cancer
Q48518399Fluorescently-tagged human eIF3 for single-molecule spectroscopy
Q34056518Functional and biochemical characterization of human eukaryotic translation initiation factor 3 in living cells
Q27680505Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit
Q36972906Heterogeneity of the translational machinery: Variations on a common theme.
Q37644283Human eIF3: from 'blobology' to biological insight.
Q42351633Human eIF3b and eIF3a serve as the nucleation core for the assembly of eIF3 into two interconnected modules: the yeast-like core and the octamer
Q34386187Human-like eukaryotic translation initiation factor 3 from Neurospora crassa
Q42804398Interaction of p190A RhoGAP with eIF3A and Other Translation Preinitiation Factors Suggests a Role in Protein Biosynthesis.
Q35636275Mechanism of cytoplasmic mRNA translation
Q27934341Molecular architecture of the 40S⋅eIF1⋅eIF3 translation initiation complex
Q34634172Novel RNA-binding protein P311 binds eukaryotic translation initiation factor 3 subunit b (eIF3b) to promote translation of transforming growth factor β1-3 (TGF-β1-3).
Q42145681Purification of mRNA-programmed translation initiation complexes suitable for mass spectrometry analysis.
Q26738716Recent advances in the structural biology of the 26S proteasome
Q28542494Structural and biochemical characterization of the Cop9 signalosome CSN5/CSN6 heterodimer
Q27681329Structural integrity of the PCI domain of eIF3a/TIF32 is required for mRNA recruitment to the 43S pre-initiation complexes
Q27697933Structure of a yeast 40S-eIF1-eIF1A-eIF3-eIF3j initiation complex
Q34492793Structure of mammalian eIF3 in the context of the 43S preinitiation complex
Q51410878The Jigsaw Puzzle of mRNA Translation Initiation in Eukaryotes: A Decade of Structures Unraveling the Mechanics of the Process.
Q35885901The eIF3 complex of Leishmania-subunit composition and mode of recruitment to different cap-binding complexes.
Q39175805The eIF3 complex of Trypanosoma brucei: composition conservation does not imply the conservation of structural assembly and subunits function
Q35533889The translation initiation complex eIF3 in trypanosomatids and other pathogenic excavates--identification of conserved and divergent features based on orthologue analysis
Q28535333Translation initiation factors eIF3 and HCR1 control translation termination and stop codon read-through in yeast cells
Q28118899Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
Q41605726Unveiling Contacts within Macromolecular Assemblies by Solving Minimum Weight Connectivity Inference (MWC) Problems
Q52445969eIF3: a factor for human health and disease.

Search more.