| Q34568342 | 14-3-3Gamma inhibition of MDMX-mediated p21 turnover independent of p53. |
| Q33705055 | 14-3-3Tau regulates ubiquitin-independent proteasomal degradation of p21, a novel mechanism of p21 downregulation in breast cancer |
| Q39821184 | A cellular model to monitor proteasome dysfunction by alpha-synuclein |
| Q37472304 | A critical evaluation of the ubiquitin-proteasome system in Parkinson's disease |
| Q40324090 | A mathematical model of protein degradation by the proteasome |
| Q27933912 | A multimeric assembly factor controls the formation of alternative 20S proteasomes |
| Q40174315 | A novel protein-processing domain in Gli2 and Gli3 differentially blocks complete protein degradation by the proteasome |
| Q40433173 | A precipitating role for truncated alpha-synuclein and the proteasome in alpha-synuclein aggregation: implications for pathogenesis of Parkinson disease |
| Q42177637 | A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel |
| Q39414304 | AAA-ATPases in Protein Degradation. |
| Q41127007 | APC/C(Cdc20) controls the ubiquitin-mediated degradation of p21 in prometaphase |
| Q33999948 | ATP binding and ATP hydrolysis play distinct roles in the function of 26S proteasome |
| Q34358218 | Abnormal neurites containing C-terminally truncated alpha-synuclein are present in Alzheimer's disease without conventional Lewy body pathology. |
| Q35698432 | Accelerated formation of alpha-synuclein oligomers by concerted action of the 20S proteasome and familial Parkinson mutations |
| Q35128280 | Actin cytoskeleton remodeling by the alternatively spliced isoform of PDLIM4/RIL protein. |
| Q27664573 | Acyldepsipeptide antibiotics induce the formation of a structured axial channel in ClpP: A model for the ClpX/ClpA-bound state of ClpP. |
| Q39415233 | Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells |
| Q33836384 | Aggregation promoting C-terminal truncation of alpha-synuclein is a normal cellular process and is enhanced by the familial Parkinson's disease-linked mutations |
| Q36297055 | Aging and regulated protein degradation: who has the UPPer hand? |
| Q36212686 | Aging perturbs 26S proteasome assembly in Drosophila melanogaster |
| Q46948329 | An AAA protease FtsH can initiate proteolysis from internal sites of a model substrate, apo-flavodoxin |
| Q27677216 | An Archaeal Homolog of Proteasome Assembly Factor Functions as a Proteasome Activator |
| Q34564542 | An antigen produced by splicing of noncontiguous peptides in the reverse order. |
| Q45018402 | An unstructured initiation site is required for efficient proteasome-mediated degradation |
| Q40263720 | Archaeal proteasomes effectively degrade aggregation-prone proteins and reduce cellular toxicities in mammalian cells |
| Q35209250 | Archaeal proteasomes: potential in metabolic engineering |
| Q36517148 | Astrocyte-specific overexpression of Nrf2 delays motor pathology and synuclein aggregation throughout the CNS in the alpha-synuclein mutant (A53T) mouse model |
| Q101216242 | Blood coagulation factor VIII D1241E polymorphism leads to a weak malectin interaction and reduction of factor VIII posttranslational modification and secretion |
| Q57986252 | C-terminal truncation of α-synuclein promotes amyloid fibril amplification at physiological pH |
| Q40107851 | Ceramide-induced G2 arrest in rhabdomyosarcoma (RMS) cells requires p21Cip1/Waf1 induction and is prevented by MDM2 overexpression |
| Q50748831 | Characterization of rapidly degraded polypeptides in mammalian cells reveals a novel layer of nascent protein quality control. |
| Q40353124 | Chemical blockage of the proteasome inhibitory function of bortezomib: impact on tumor cell death |
| Q22061736 | Classification of intrinsically disordered regions and proteins |
| Q44777524 | Clearance of alpha-synuclein oligomeric intermediates via the lysosomal degradation pathway. |
| Q27939996 | Complementary roles for Rpn11 and Ubp6 in deubiquitination and proteolysis by the proteasome |
| Q37875825 | Context-dependent resistance to proteolysis of intrinsically disordered proteins |
| Q38704492 | DT-diaphorase Protects Against Autophagy Induced by Aminochrome-Dependent Alpha-Synuclein Oligomers. |
| Q38021167 | Degradation of damaged proteins: the main function of the 20S proteasome |
| Q35152946 | Degradation of misfolded proteins in neurodegenerative diseases: therapeutic targets and strategies |
| Q39540114 | Degradation of some polyubiquitinated proteins requires an intrinsic proteasomal binding element in the substrates |
| Q30415416 | Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals |
| Q28652765 | Disordered proteinaceous machines |
| Q35902695 | Disruption of protein quality control in Parkinson's disease |
| Q27930024 | Dissecting the ER-associated degradation of a misfolded polytopic membrane protein |
| Q27938024 | Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein |
| Q36653589 | Distinct roles in vivo for the ubiquitin-proteasome system and the autophagy-lysosomal pathway in the degradation of α-synuclein |
| Q27660397 | Dynamic regulation of archaeal proteasome gate opening as studied by TROSY NMR |
| Q39809467 | Effects of stability on the biological function of p53. |
| Q44619763 | Epstein–Barr virus can inhibit genotoxin-induced G1 arrest downstream of p53 by preventing the inactivation of CDK2 |
| Q38433969 | Establishment of a suite of assays that support the discovery of proteasome stimulators |
| Q24300071 | FAT10, a ubiquitin-independent signal for proteasomal degradation |
| Q42122935 | Force spectroscopy of substrate molecules en route to the proteasome's active sites |
| Q24307429 | Function of the p97-Ufd1-Npl4 complex in retrotranslocation from the ER to the cytosol: dual recognition of nonubiquitinated polypeptide segments and polyubiquitin chains |
| Q45057099 | Functional consequences of alpha-synuclein tyrosine nitration: diminished binding to lipid vesicles and increased fibril formation. |
| Q39659854 | Functional dissection of the N-terminal degron of human thymidylate synthase |
| Q35815962 | Functions of NF-kappaB1 and NF-kappaB2 in immune cell biology |
| Q37142562 | Gly-Ala repeats induce position- and substrate-specific regulation of 26 S proteasome-dependent partial processing |
| Q24543904 | Glycine-alanine repeats impair proper substrate unfolding by the proteasome |
| Q38177328 | Harnessing proteasome dynamics and allostery in drug design. |
| Q36381253 | Highbrow proteasome in high-throughput technology |
| Q34519869 | Histone deacetylase inhibitors induce VHL and ubiquitin-independent proteasomal degradation of hypoxia-inducible factor 1alpha |
| Q40335511 | Hzf, a p53-responsive gene, regulates maintenance of the G2 phase checkpoint induced by DNA damage |
| Q39738969 | Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling. |
| Q60047569 | Inhibition of the Neuronal Calcium Sensor DREAM Modulates Presenilin-2 Endoproteolysis |
| Q35179432 | Integration of the proteasome inhibitor PS-341 (Velcade) into the therapeutic approach to lung cancer |
| Q26784629 | Intracellular Dynamics of the Ubiquitin-Proteasome-System |
| Q34438593 | Intrinsically disordered segments affect protein half-life in the cell and during evolution |
| Q34117465 | LYL1 degradation by the proteasome is directed by a N-terminal PEST rich site in a phosphorylation-independent manner |
| Q38214413 | Less understood issues: p21(Cip1) in mitosis and its therapeutic potential. |
| Q40034309 | MDMX promotes proteasomal turnover of p21 at G1 and early S phases independently of, but in cooperation with, MDM2. |
| Q36100354 | Mannose 6-Phosphate Receptor Is Reduced in -Synuclein Overexpressing Models of Parkinsons Disease |
| Q42482608 | Mechanism of direct degradation of IkappaBalpha by 20S proteasome |
| Q37029653 | Metabolic control of proteasome function |
| Q37202220 | Modulation of growth hormone receptor abundance and function: roles for the ubiquitin-proteasome system |
| Q81453964 | Monitoring activity and inhibition of 26S proteasomes with fluorogenic peptide substrates |
| Q39605257 | Multiple cytosolic and transmembrane determinants are required for the trafficking of SCAMP1 via an ER-Golgi-TGN-PM pathway |
| Q33793002 | Multiple sclerosis autoantigen myelin basic protein escapes control by ubiquitination during proteasomal degradation |
| Q41493138 | Multisite protein kinase A and glycogen synthase kinase 3beta phosphorylation leads to Gli3 ubiquitination by SCFbetaTrCP. |
| Q24563960 | N-Terminal ubiquitination of extracellular signal-regulated kinase 3 and p21 directs their degradation by the proteasome |
| Q30436358 | N-glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase |
| Q33303325 | N-linked glycosylation does not impair proteasomal degradation but affects class I major histocompatibility complex presentation |
| Q24561681 | N-terminal polyubiquitination and degradation of the Arf tumor suppressor |
| Q43107129 | N-terminal α7 deletion of the proteasome 20S core particle substitutes for yeast PI31 function |
| Q60956587 | NGF-Dependent Changes in Ubiquitin Homeostasis Trigger Early Cholinergic Degeneration in Cellular and Animal AD-Model |
| Q37311396 | Natural polyphenols as proteasome modulators and their role as anti-cancer compounds. |
| Q33799579 | Neonatal hyperoxia stimulates the expansion of alveolar epithelial type II cells |
| Q35790783 | Novel targeted agents in the treatment of lung cancer |
| Q34785777 | Nuclear transport of yeast proteasomes |
| Q36675188 | Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation |
| Q43752239 | Overexpression of synphilin-1 promotes clearance of soluble and misfolded alpha-synuclein without restoring the motor phenotype in aged A30P transgenic mice |
| Q40086578 | Oxygen-dependent changes in lung development do not affect epithelial infection with influenza A virus. |
| Q35072849 | PaCS is a novel cytoplasmic structure containing functional proteasome and inducible by cytokines/trophic factors |
| Q38079791 | Parkinson's disease and alpha synuclein: is Parkinson's disease a prion-like disorder? |
| Q37882593 | Parkinson's disease, proteins, and prions: milestones |
| Q26998855 | Particle-rich cytoplasmic structure (PaCS): identification, natural history, role in cell biology and pathology |
| Q48586171 | Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. |
| Q39642185 | Phosphorylated α-Synuclein at Ser-129 Is Targeted to the Proteasome Pathway in a Ubiquitin-independent Manner |
| Q27929878 | Phosphorylation regulates the ubiquitin-independent degradation of yeast Pah1 phosphatidate phosphatase by the 20S proteasome |
| Q26823798 | Physicochemical properties of cells and their effects on intrinsically disordered proteins (IDPs) |
| Q34233869 | Plastidial starch phosphorylase in sweet potato roots is proteolytically modified by protein-protein interaction with the 20S proteasome |
| Q39977321 | Pre-folding IkappaBalpha alters control of NF-kappaB signaling |
| Q47583613 | Probing the cooperativity of Thermoplasma acidophilum proteasome core particle gating by NMR spectroscopy |
| Q51600378 | Proteasomal activities in the claw muscle tissue of European lobster, Homarus gammarus, during larval development. |
| Q35420913 | Proteasomal degradation from internal sites favors partial proteolysis via remote domain stabilization |
| Q42166737 | Proteasome disassembly and downregulation is correlated with viability during stationary phase |
| Q24310109 | Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6 |
| Q42208073 | Proteasome substrate degradation requires association plus extended peptide |
| Q39490796 | Proteasome-mediated cleavage of the Y-box-binding protein 1 is linked to DNA-damage stress response |
| Q34268195 | Proteasome-mediated degradation of p21 via N-terminal ubiquitinylation. |
| Q79918110 | Proteasome-mediated protein processing by bidirectional degradation initiated from an internal site |
| Q29614359 | Proteasomes and their kin: proteases in the machine age |
| Q27932737 | Proteasomes can degrade a significant proportion of cellular proteins independent of ubiquitination |
| Q36597934 | Proteasomes from structure to function: perspectives from Archaea |
| Q47903181 | Protein Modifications with Ubiquitin as Response to Cerebral Ischemia-Reperfusion Injury |
| Q27026029 | Protein degradation pathways in Parkinson's disease: curse or blessing |
| Q35756661 | Protein disulfide isomerases contribute differentially to the endoplasmic reticulum-associated degradation of apolipoprotein B and other substrates |
| Q37085193 | Protein targeting to ATP-dependent proteases |
| Q82029470 | Protein-handling dysfunction in Parkinson's disease |
| Q35941669 | Proteolytic dysfunction in neurodegenerative disorders |
| Q44970215 | Pyrrolidine dithiocarbamate and zinc inhibit proteasome-dependent proteolysis |
| Q59082478 | Quantitative dynamics and binding studies of the 20S proteasome by NMR |
| Q38954061 | Rapid proteasomal degradation of posttranscriptional regulators of the TIS11/tristetraprolin family is induced by an intrinsically unstructured region independently of ubiquitination. |
| Q29547616 | Recognition and processing of ubiquitin-protein conjugates by the proteasome |
| Q42124117 | Redox control of 20S proteasome gating |
| Q38176369 | Redox regulation of the proteasome via S-glutathionylation. |
| Q92409566 | Regulation of Proteasome Activity by (Post-)transcriptional Mechanisms |
| Q33974768 | Repeat sequence of Epstein-Barr virus-encoded nuclear antigen 1 protein interrupts proteasome substrate processing |
| Q35548597 | Role of ubiquitin-mediated proteolysis in the pathogenesis of neurodegenerative disorders. |
| Q35510197 | Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease. |
| Q38761956 | Sequence-based analysis of protein degradation rates. |
| Q38462113 | Sirtuins and proteolytic systems: implications for pathogenesis of synucleinopathies |
| Q36876982 | Site-specific methionine oxidation initiates calmodulin degradation by the 20S proteasome |
| Q42260449 | Slippery substrates impair ATP-dependent protease function by slowing unfolding |
| Q44478783 | Stability of the Rel homology domain is critical for generation of NF-kappa B p50 subunit |
| Q38081952 | Structural biology of the proteasome |
| Q43131503 | Structure and function of a novel type of ATP-dependent Clp protease |
| Q93087626 | Substrate processing by the Cdc48 ATPase complex is initiated by ubiquitin unfolding |
| Q42680947 | Susceptibility of p53 unstructured N terminus to 20 S proteasomal degradation programs the stress response. |
| Q50554031 | Synphilin-1 inhibits alpha-synuclein degradation by the proteasome. |
| Q63529367 | TBP-1 protects the human oncosuppressor p14ARF from proteasomal degradation |
| Q28261886 | Targeting proteins for degradation |
| Q42703666 | The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner |
| Q28295352 | The C Terminus of Rpt3, an ATPase Subunit of PA700 (19 S) Regulatory Complex, Is Essential for 26 S Proteasome Assembly but Not for Activation |
| Q64997878 | The Contribution of the 20S Proteasome to Proteostasis. |
| Q35833984 | The Interplay between Alpha-Synuclein Clearance and Spreading |
| Q51736947 | The N terminus of Autographa californica Multiple Nucleopolyhedrovirus DNA Polymerase is Required for Efficient Viral DNA Replication and Virus and Occlusion Body Production. |
| Q38996038 | The Proteasome Inhibition Model of Parkinson's Disease |
| Q38132669 | The RNA exosome and proteasome: common principles of degradation control |
| Q24302180 | The SRC-3/AIB1 coactivator is degraded in a ubiquitin- and ATP-independent manner by the REGgamma proteasome |
| Q36386004 | The archaeal proteasome is regulated by a network of AAA ATPases |
| Q37401466 | The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. |
| Q24676115 | The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system |
| Q39264914 | The direction of protein entry into the proteasome determines the variety of products and depends on the force needed to unfold its two termini. |
| Q24323509 | The otubain YOD1 is a deubiquitinating enzyme that associates with p97 to facilitate protein dislocation from the ER |
| Q44216424 | The proteasome antechamber maintains substrates in an unfolded state |
| Q36472495 | The proteasome: overview of structure and functions |
| Q39155657 | The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1. |
| Q37100233 | The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum |
| Q53847738 | The role of exoproteases in governing intraneuronal metabolism of botulinum toxin. |
| Q28305844 | The ubiquitin-proteasome system |
| Q34535073 | The ubiquitin-proteasome system and autophagy: Coordinated and independent activities |
| Q56774478 | Thermo-resistant intrinsically disordered proteins are efficient 20S proteasome substrates |
| Q41246990 | Toward an understanding of the Cdc48/p97 ATPase |
| Q44665413 | Transcobalamin deficiency due to activation of an intra exonic cryptic splice site |
| Q41062674 | Two-substrate association with the 20S proteasome at single-molecule level |
| Q24537149 | Ubiquilin regulates presenilin endoproteolysis and modulates gamma-secretase components, Pen-2 and nicastrin |
| Q36799954 | Ubiquitin and proteasomes in transcription |
| Q46005002 | Ubiquitin orchestrates proteasome dynamics between proliferation and quiescence in yeast. |
| Q34699448 | Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma |
| Q39715640 | Ubiquitin-independent degradation of antiapoptotic MCL-1. |
| Q37033367 | Ubiquitin-independent degradation of hepatitis C virus F protein |
| Q35152119 | Ubiquitin-independent proteolytic functions of the proteasome |
| Q44552114 | Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function |
| Q44504087 | Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD. |
| Q57851819 | Where to start and when to stop |
| Q53611928 | Widespread, but non-identical, association of proteasomal 19 and 20 S proteins with yeast chromatin. |
| Q38039881 | α-Synuclein and protein degradation systems: a reciprocal relationship |
| Q35558701 | α-Synuclein fate is determined by USP9X-regulated monoubiquitination |
| Q38038123 | α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration |