scholarly article | Q13442814 |
P50 | author | Fabio Luciani | Q37829037 |
Michele Mishto | Q41050022 | ||
P2093 | author name string | Can Keşmir | |
Michal Or-Guil | |||
Rob J de Boer | |||
P2860 | cites work | 26S proteasomes and immunoproteasomes produce mainly N-extended versions of an antigenic peptide | Q24535312 |
Structural basis for the activation of 20S proteasomes by 11S regulators | Q27628418 | ||
Crystal structure of the 20S proteasome from the archaeon T. acidophilum at 3.4 A resolution | Q27730197 | ||
Structure of 20S proteasome from yeast at 2.4 A resolution | Q27735081 | ||
The axial channel of the proteasome core particle is gated by the Rpt2 ATPase and controls both substrate entry and product release | Q27933726 | ||
The active sites of the eukaryotic 20 S proteasome and their involvement in subunit precursor processing | Q27939678 | ||
Pathway for degradation of peptides generated by proteasomes: a key role for thimet oligopeptidase and other metallopeptidases | Q28278713 | ||
Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products | Q30685494 | ||
Why does threonine, and not serine, function as the active site nucleophile in proteasomes? | Q30870481 | ||
Cleavage motifs of the yeast 20S proteasome beta subunits deduced from digests of enolase 1. | Q32000515 | ||
The proteasome, a novel protease regulated by multiple mechanisms | Q33700949 | ||
The proteasome activator 11 S REG (PA28) and class I antigen presentation | Q33796158 | ||
Getting in and out of the proteasome | Q33975540 | ||
Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. | Q34088438 | ||
Not such a dismal science: the economics of protein synthesis, folding, degradation and antigen processing | Q34286224 | ||
Proteasome from Thermoplasma acidophilum: a threonine protease | Q34309062 | ||
A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation. | Q34313503 | ||
Substrate access and processing by the 20S proteasome core particle | Q35097624 | ||
Making sense of mass destruction: quantitating MHC class I antigen presentation | Q35597106 | ||
Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII. | Q35821221 | ||
Efficient generation of a hepatitis B virus cytotoxic T lymphocyte epitope requires the structural features of immunoproteasomes | Q36375899 | ||
Endoproteolytic activity of the proteasome | Q36450745 | ||
A role for the proteasome regulator PA28alpha in antigen presentation | Q38357921 | ||
A kinetic model of vertebrate 20S proteasome accounting for the generation of major proteolytic fragments from oligomeric peptide substrates | Q40169547 | ||
Quantitative analysis of prion-protein degradation by constitutive and immuno-20S proteasomes indicates differences correlated with disease susceptibility | Q40602088 | ||
Kinetic evidences for facilitation of peptide channelling by the proteasome activator PA28. | Q40851962 | ||
Differential influence on cytotoxic T lymphocyte epitope presentation by controlled expression of either proteasome immunosubunits or PA28 | Q40859882 | ||
Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes | Q41027912 | ||
Two-substrate association with the 20S proteasome at single-molecule level | Q41062674 | ||
Proteasome-cytochrome c interactions: a model system for investigation of proteasome host-guest interactions | Q43033893 | ||
Proteins are unfolded on the surface of the ATPase ring before transport into the proteasome | Q43846790 | ||
Binding of hydrophobic peptides to several non-catalytic sites promotes peptide hydrolysis by all active sites of 20 S proteasomes. Evidence for peptide-induced channel opening in the alpha-rings | Q43943338 | ||
Prediction of proteasome cleavage motifs by neural networks | Q43976304 | ||
Assessment of proteasomal cleavage probabilities from kinetic analysis of time-dependent product formation | Q44021101 | ||
Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel | Q44038790 | ||
Substrate size selectivity of 20S proteasomes: analysis with variable-sized synthetic substrates | Q44121715 | ||
Proteasome-mediated degradation of tau proteins occurs independently of the chymotrypsin-like activity by a nonprocessive pathway | Q44251448 | ||
Bioinformatic analysis of functional differences between the immunoproteasome and the constitutive proteasome | Q44573284 | ||
Proteasome degradation: enter the substrate | Q44628364 | ||
Cleaving proteins for the immune system | Q44757947 | ||
Proteasomes begin ornithine decarboxylase digestion at the C terminus | Q44797041 | ||
Regulation of the peptidylglutamyl-peptide hydrolyzing activity of the pituitary multicatalytic proteinase complex | Q46776563 | ||
Evidence that the nature of amino acid residues in the P3 position directs substrates to distinct catalytic sites of the pituitary multicatalytic proteinase complex (proteasome). | Q48120291 | ||
Components of the bovine pituitary multicatalytic proteinase complex (proteasome) cleaving bonds after hydrophobic residues | Q48151424 | ||
Bovine spleen multicatalytic proteinase complex (proteasome). Replacement of X, Y, and Z subunits by LMP7, LMP2, and MECL1 and changes in properties and specificity | Q48708926 | ||
The human 26 S and 20 S proteasomes generate overlapping but different sets of peptide fragments from a model protein substrate. | Q51081014 | ||
Kinetic characterization of the chymotryptic activity of the 20S proteasome. | Q52306880 | ||
Catalytic Properties of 26 S and 20 S Proteasomes and Radiolabeling of MB1, LMP7, and C7 Subunits Associated with Trypsin-like and Chymotrypsin-like Activities | Q61941012 | ||
Peptidylglutamyl-peptide hydrolase activity of the multicatalytic proteinase complex: evidence for a new high-affinity site, analysis of cooperative kinetics, and the effect of manganese ions | Q68099962 | ||
Coordinated dual cleavages induced by the proteasome regulator PA28 lead to dominant MHC ligands | Q71254579 | ||
Nucleotidase activities of the 26 S proteasome and its regulatory complex | Q71859921 | ||
Processive degradation of proteins and other catalytic properties of the proteasome from Thermoplasma acidophilum | Q71985039 | ||
Lysozyme degradation by the bovine multicatalytic proteinase complex (proteasome): evidence for a nonprocessive mode of degradation | Q73141722 | ||
Characterization of recombinant REGalpha, REGbeta, and REGgamma proteasome activators | Q73770368 | ||
Evidence for the existence of a non-catalytic modifier site of peptide hydrolysis by the 20 S proteasome | Q73778113 | ||
Range of sizes of peptide products generated during degradation of different proteins by archaeal proteasomes | Q74088744 | ||
Decelerated degradation of short peptides by the 20S proteasome | Q77317960 | ||
High-resolution AFM-imaging and mechanistic analysis of the 20 S proteasome | Q77753783 | ||
The sizes of peptides generated from protein by mammalian 26 and 20 S proteasomes. Implications for understanding the degradative mechanism and antigen presentation | Q77911981 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | mathematical model | Q486902 |
P304 | page(s) | 2422-2432 | |
P577 | publication date | 2005-01-21 | |
P1433 | published in | Biophysical Journal | Q2032955 |
P1476 | title | A mathematical model of protein degradation by the proteasome | |
P478 | volume | 88 |
Q50740999 | 20S proteasomes have the potential to keep substrates in store for continual degradation. |
Q48588098 | A structural model of 20S immunoproteasomes: effect of LMP2 codon 60 polymorphism on expression, activity, intracellular localisation and insight into the regulatory mechanisms |
Q35603112 | A systems view of the protein expression process |
Q42162926 | Crystallization and preliminary X-ray analysis of the Thermoplasma acidophilum 20S proteasome in complex with protein substrates |
Q38828129 | Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways. |
Q42122935 | Force spectroscopy of substrate molecules en route to the proteasome's active sites |
Q33912642 | Modelling proteasome and proteasome regulator activities. |
Q39234159 | Novel Proteasome Inhibitors and Histone Deacetylase Inhibitors: Progress in Myeloma Therapeutics |
Q42019078 | Optimal length transportation hypothesis to model proteasome product size distribution |
Q38202977 | Proteasome inhibitors - molecular basis and current perspectives in multiple myeloma |
Q38667315 | Proteasome properties of hemocytes differ between the whiteleg shrimp Penaeus vannamei and the brown shrimp Crangon crangon (Crustacea, Decapoda). |
Q41189449 | Proteostasis, oxidative stress and aging |
Q33627497 | The 20S proteasome splicing activity discovered by SpliceMet |
Q64069427 | Untangling Extracellular Proteasome-Osteopontin Circuit Dynamics in Multiple Sclerosis |
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