| scholarly article | Q13442814 |
| review article | Q7318358 |
| P50 | author | José Pedro Castro | Q92616183 |
| Tilman Grune | Q42577412 | ||
| Annika Höhn | Q47503915 | ||
| Tobias Jung | Q48013635 | ||
| Martín Hugo | Q54023035 | ||
| Daniela Weber | Q56383616 | ||
| P2093 | author name string | Ioanna Korovila | |
| P2860 | cites work | Protein oxidation and aging | Q79336883 |
| Proteasome response to interferon-gamma is altered in senescent human fibroblasts | Q79808258 | ||
| Proteasome-mediated CCAAT/enhancer-binding protein delta (C/EBPdelta) degradation is ubiquitin-independent | Q79993235 | ||
| Overexpression of proteasome beta5 assembled subunit increases the amount of proteasome and confers ameliorated response to oxidative stress and higher survival rates | Q81300121 | ||
| Age-related loss of stress-induced nuclear proteasome activation is due to low PARP-1 activity | Q82066538 | ||
| The Immunoproteasome Cleans up after Inflammation | Q84772673 | ||
| Analyzing the Colocalization of MAP1LC3 and Lysosomal Markers in Primary Cells | Q86052253 | ||
| Heat shock proteins and proteasomal degradation in normal and tumor cells | Q86456783 | ||
| Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation | Q24337474 | ||
| Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases | Q24564109 | ||
| Distinct consequences of posttranslational modification by linear versus K63-linked polyubiquitin chains | Q24621713 | ||
| The chaperone-mediated autophagy receptor organizes in dynamic protein complexes at the lysosomal membrane | Q24646454 | ||
| Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways | Q24647626 | ||
| The peroxiredoxin repair proteins | Q24652194 | ||
| Restoration of chaperone-mediated autophagy in aging liver improves cellular maintenance and hepatic function | Q24655432 | ||
| Methionine residues as endogenous antioxidants in proteins | Q24658367 | ||
| Recent advances in the structural biology of the 26S proteasome | Q26738716 | ||
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| Adaptive homeostasis | Q26750503 | ||
| Lysosomal signaling in control of degradation pathways | Q26772949 | ||
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| Non-canonical ubiquitin-based signals for proteasomal degradation | Q26825366 | ||
| RING-type E3 ligases: master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination | Q26850008 | ||
| The basics of thiols and cysteines in redox biology and chemistry | Q26991843 | ||
| Immunoproteasomes: structure, function, and antigen presentation | Q27024527 | ||
| Peroxiredoxins: guardians against oxidative stress and modulators of peroxide signaling | Q27026271 | ||
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| The structure of the mammalian 20S proteasome at 2.75 A resolution | Q27638997 | ||
| The immunoproteasome and viral infection: a complex regulator of inflammation | Q27694656 | ||
| Identification of the yeast 20S proteasome catalytic centers and subunit interactions required for active-site formation | Q27932645 | ||
| A lysosome-centered view of nutrient homeostasis | Q28073435 | ||
| Transcriptional and epigenetic regulation of autophagy in aging | Q28083637 | ||
| Essential role for autophagy in life span extension | Q28085050 | ||
| Differential regulation of distinct Vps34 complexes by AMPK in nutrient stress and autophagy | Q28115189 | ||
| Regulation of CD8+ T cell development by thymus-specific proteasomes | Q28116400 | ||
| Lipofuscin is formed independently of macroautophagy and lysosomal activity in stress-induced prematurely senescent human fibroblasts | Q28118094 | ||
| Purification of an 11 S regulator of the multicatalytic protease | Q28202111 | ||
| Proteasome-mediated processing of Nrf1 is essential for coordinate induction of all proteasome subunits and p97 | Q28243388 | ||
| Autophagy-mediated longevity is modulated by lipoprotein biogenesis | Q36810995 | ||
| Antioxidants Enhance Mammalian Proteasome Expression through the Keap1-Nrf2 Signaling Pathway | Q37062266 | ||
| Lipofuscin: formation, effects and role of macroautophagy | Q37133485 | ||
| The Immunoproteasome in oxidative stress, aging, and disease. | Q37141580 | ||
| Mixed proteasomes function to increase viral peptide diversity and broaden antiviral CD8+ T cell responses | Q37146941 | ||
| Poly-ADP ribose polymerase activates nuclear proteasome to degrade oxidatively damaged histones | Q37202186 | ||
| REGgamma, a proteasome activator and beyond? | Q37235077 | ||
| Activation of Nrf2-antioxidant signaling attenuates NFkappaB-inflammatory response and elicits apoptosis | Q37241323 | ||
| Targeting proteins for destruction by the ubiquitin system: implications for human pathobiology | Q37286190 | ||
| Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction | Q37302762 | ||
| S-glutathionylation of the Rpn2 regulatory subunit inhibits 26 S proteasomal function | Q37372263 | ||
| 18α-Glycyrrhetinic Acid Proteasome Activator Decelerates Aging and Alzheimer's Disease Progression in Caenorhabditis elegans and Neuronal Cultures | Q37443865 | ||
| The proteasomal system. | Q37446143 | ||
| Methionine sulfoxides in serum proteins as potential clinical biomarkers of oxidative stress | Q37483905 | ||
| The molecular chaperone Hsp70 promotes the proteolytic removal of oxidatively damaged proteins by the proteasome. | Q37545942 | ||
| Macroautophagy signaling and regulation | Q37608022 | ||
| Functional analysis of lysosomes during mouse preimplantation embryo development | Q37618788 | ||
| Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems | Q37664227 | ||
| Chaperone-mediated autophagy: machinery, regulation and biological consequences | Q37803152 | ||
| The Ubiquitin System and Kaposi's Sarcoma-Associated Herpesvirus | Q37989143 | ||
| Changes of the proteasomal system during the aging process. | Q38021168 | ||
| The Nrf2 cell defence pathway: Keap1-dependent and -independent mechanisms of regulation | Q38065567 | ||
| Structural biology of the proteasome | Q38081952 | ||
| Relationship between the proteasomal system and autophagy | Q38103557 | ||
| The MHC I loading complex: a multitasking machinery in adaptive immunity | Q38121190 | ||
| The proteasome and the degradation of oxidized proteins: Part I-structure of proteasomes. | Q38136226 | ||
| Early signalling events of autophagy | Q38144264 | ||
| Selective autophagy | Q38144281 | ||
| The nrf1 and nrf2 balance in oxidative stress regulation and androgen signaling in prostate cancer cells | Q38166575 | ||
| The machinery of macroautophagy | Q38173673 | ||
| Redox regulation of the proteasome via S-glutathionylation. | Q38176369 | ||
| Mechanisms for regulating deubiquitinating enzymes | Q38176851 | ||
| The proteasome and the degradation of oxidized proteins: part III-Redox regulation of the proteasomal system | Q38190556 | ||
| Melatonin feedback on clock genes: a theory involving the proteasome | Q38264948 | ||
| Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules | Q28248180 | ||
| Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells | Q28279454 | ||
| Proteasomal Degradation Is Transcriptionally Controlled by TCF11 via an ERAD-Dependent Feedback Loop | Q28295179 | ||
| p97-dependent retrotranslocation and proteolytic processing govern formation of active Nrf1 upon proteasome inhibition | Q28306282 | ||
| Evolution of proteasome regulators in eukaryotes | Q28334391 | ||
| Regulation of cell function by methionine oxidation and reduction | Q28349109 | ||
| Redox regulation of mitochondrial function | Q28383361 | ||
| The Keap1-Nrf2 pathway: Mechanisms of activation and dysregulation in cancer | Q28387975 | ||
| The complexity of the Nrf2 pathway: beyond the antioxidant response | Q28389296 | ||
| Regulation of proteasome activity in health and disease | Q28392708 | ||
| Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells | Q28394410 | ||
| Microautophagy of cytosolic proteins by late endosomes | Q28509224 | ||
| Altered proteasome function and subunit composition in aged muscle | Q28565158 | ||
| Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions | Q28575853 | ||
| Selective autophagy: xenophagy | Q28652564 | ||
| Induction of autophagy by spermidine promotes longevity | Q29614498 | ||
| Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple | Q29615232 | ||
| The unfolded protein response: controlling cell fate decisions under ER stress and beyond | Q29615499 | ||
| Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism | Q29619866 | ||
| Inflammation meets cancer, with NF-κB as the matchmaker | Q29620242 | ||
| Methionine residues may protect proteins from critical oxidative damage. | Q30322097 | ||
| HSPA8/HSC70 chaperone protein: structure, function, and chemical targeting. | Q30354473 | ||
| Catalytic site-specific inhibition of the 20S proteasome by 4-hydroxynonenal | Q31135318 | ||
| The IKK complex, a central regulator of NF-kappaB activation | Q33693802 | ||
| Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts | Q33707090 | ||
| Mining the TRAF6/p62 interactome for a selective ubiquitination motif | Q33893441 | ||
| Uric acid: the oxidant-antioxidant paradox | Q33956678 | ||
| Methionine oxidation and aging | Q33984659 | ||
| Assembly, structure, and function of the 26S proteasome. | Q33988314 | ||
| Conformational constraints in protein degradation by the 20S proteasome | Q34058982 | ||
| An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes | Q34063163 | ||
| Properties of the hybrid form of the 26S proteasome containing both 19S and PA28 complexes. | Q34088438 | ||
| Catalytic activities of the 20 S proteasome, a multicatalytic proteinase complex | Q34092896 | ||
| Microautophagy: lesser-known self-eating | Q34232209 | ||
| Chaperones, but not oxidized proteins, are ubiquitinated after oxidative stress | Q34298650 | ||
| Signals from the lysosome: a control centre for cellular clearance and energy metabolism | Q34340780 | ||
| Autophagy and ageing: implications for age-related neurodegenerative diseases. | Q34373575 | ||
| PSMB8 encoding the β5i proteasome subunit is mutated in joint contractures, muscle atrophy, microcytic anemia, and panniculitis-induced lipodystrophy syndrome | Q34381697 | ||
| Chaperone-mediated autophagy: roles in disease and aging | Q34388237 | ||
| Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway | Q34400761 | ||
| Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging | Q34556311 | ||
| NF-kappaB/p65 antagonizes Nrf2-ARE pathway by depriving CBP from Nrf2 and facilitating recruitment of HDAC3 to MafK. | Q34744211 | ||
| Dependence of proteasome processing rate on substrate unfolding | Q34978877 | ||
| Ubiquitin-proteasome pathway and cellular responses to oxidative stress | Q35027877 | ||
| 20S proteasome activation promotes life span extension and resistance to proteotoxicity in Caenorhabditis elegans | Q35039312 | ||
| Proteasome assembly defect due to a proteasome subunit beta type 8 (PSMB8) mutation causes the autoinflammatory disorder, Nakajo-Nishimura syndrome. | Q35202606 | ||
| Peroxiredoxin 3 is a key molecule regulating adipocyte oxidative stress, mitochondrial biogenesis, and adipokine expression. | Q35604034 | ||
| Lifespan of mice and primates correlates with immunoproteasome expression | Q35720093 | ||
| Induction and adaptation of chaperone-assisted selective autophagy CASA in response to resistance exercise in human skeletal muscle | Q35852833 | ||
| Age-dependent inhibition of proteasome chymotrypsin-like activity in the retina | Q35858136 | ||
| Nrf2-dependent induction of proteasome and Pa28αβ regulator are required for adaptation to oxidative stress | Q35880062 | ||
| Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes | Q36177598 | ||
| Dissecting molecular cross-talk between Nrf2 and NF-κB response pathways | Q36184638 | ||
| Proteasome function is not impaired in healthy aging of the lung | Q36260235 | ||
| NF-κB controls energy homeostasis and metabolic adaptation by upregulating mitochondrial respiration | Q36291524 | ||
| mTORC1 maintains metabolic balance | Q36293517 | ||
| Coordinate regulation of the human TAP1 and LMP2 genes from a shared bidirectional promoter | Q36364703 | ||
| Chaperones in autophagy | Q36413186 | ||
| Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2. | Q36512148 | ||
| Constitutive activation of chaperone-mediated autophagy in cells with impaired macroautophagy | Q36631143 | ||
| Proteasomal adaptation to environmental stress links resistance to proteotoxicity with longevity in Caenorhabditis elegans | Q36657540 | ||
| Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection | Q36799097 | ||
| Standard and immunoproteasomes show similar peptide degradation specificities. | Q38268527 | ||
| S-glutathionylation reactions in mitochondrial function and disease | Q38276703 | ||
| The proteasome and the degradation of oxidized proteins: Part II - protein oxidation and proteasomal degradation | Q38280561 | ||
| Regulation of NADPH oxidase subunit p22(phox) by NF-kB in human aortic smooth muscle cells | Q38294991 | ||
| Role of glutathione, glutathione transferase, and glutaredoxin in regulation of redox-dependent processes. | Q38369963 | ||
| The demographics of the ubiquitin system | Q38439051 | ||
| Redox- and non-redox-metal-induced formation of free radicals and their role in human disease | Q38581859 | ||
| Targeting the lysosome in cancer | Q38645365 | ||
| The role of E3 ubiquitin-ligases MuRF-1 and MAFbx in loss of skeletal muscle mass | Q38688717 | ||
| Structural and Biological Interaction of hsc-70 Protein with Phosphatidylserine in Endosomal Microautophagy | Q38758528 | ||
| Metabolic Syndrome, Redox State, and the Proteasomal System | Q38842149 | ||
| Chaperone mediated autophagy in aging: Starve to prosper | Q38916473 | ||
| Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation | Q38955527 | ||
| Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins. | Q39352530 | ||
| Proteins bearing oxidation-induced carbonyl groups are not preferentially ubiquitinated. | Q39576384 | ||
| SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner. | Q39606140 | ||
| Ubiquitin-independent degradation of antiapoptotic MCL-1. | Q39715640 | ||
| Chromatin repair after oxidative stress: role of PARP-mediated proteasome activation | Q39760680 | ||
| Quantification of age-related changes of α-tocopherol in lysosomal membranes in murine tissues and human fibroblasts. | Q39837797 | ||
| NADH binds and stabilizes the 26S proteasomes independent of ATP. | Q39997925 | ||
| The olive constituent oleuropein exhibits proteasome stimulatory properties in vitro and confers life span extension of human embryonic fibroblasts | Q40129325 | ||
| A new infant case of Nakajo-Nishimura syndrome with a genetic mutation in the immunoproteasome subunit: an overlapping entity with JMP and CANDLE syndrome related to PSMB8 mutations. | Q40238045 | ||
| Intracellular distribution of oxidized proteins and proteasome in HT22 cells during oxidative stress. | Q40288929 | ||
| Glycogen synthase kinase-3beta inhibits the xenobiotic and antioxidant cell response by direct phosphorylation and nuclear exclusion of the transcription factor Nrf2. | Q40301567 | ||
| A mathematical model of protein degradation by the proteasome | Q40324090 | ||
| Circadian modulation of proteasome activities and removal of carbonylated proteins | Q40438284 | ||
| Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation. | Q40649321 | ||
| Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part I--effects of proliferative senescence | Q40839462 | ||
| Hydrogen peroxide-mediated protein oxidation in young and old human MRC-5 fibroblasts. | Q40899090 | ||
| Biochemical basis of lipofuscin, ceroid, and age pigment-like fluorophores | Q41197191 | ||
| Ornithine decarboxylase is degraded by the 26S proteasome without ubiquitination | Q41589996 | ||
| Mitochondrial contribution to lipofuscin formation. | Q42042230 | ||
| Macroautophagy is impaired in old murine brain tissue as well as in senescent human fibroblasts. | Q42372625 | ||
| Mitochondrial autophagy promotes healthy aging. | Q42389288 | ||
| Autophagosomes, phagosomes, autolysosomes, phagolysosomes, autophagolysosomes... wait, I'm confused | Q42729278 | ||
| Genetic evidence linking age-dependent attenuation of the 26S proteasome with the aging process | Q43179672 | ||
| Glutathiolation of the proteasome is enhanced by proteolytic inhibitors | Q43599231 | ||
| Age-dependent declines in proteasome activity in the heart | Q43857550 | ||
| Age-related increase in the immunoproteasome content in rat hippocampus: molecular and functional aspects. | Q43903490 | ||
| Stability of the nuclear protein turnover during cellular senescence of human fibroblasts | Q44535787 | ||
| Nrf1 can be processed and activated in a proteasome-independent manner | Q45043665 | ||
| Macroxyproteinase (M.O.P.): a 670 kDa proteinase complex that degrades oxidatively denatured proteins in red blood cells. | Q45054752 | ||
| Role of glutaredoxin 2 and cytosolic thioredoxins in cysteinyl-based redox modification of the 20S proteasome | Q46627706 | ||
| Identifying, by first-principles simulations, Cu[amyloid-β] species making Fenton-type reactions in Alzheimer's disease | Q46650994 | ||
| RPN-6 determines C. elegans longevity under proteotoxic stress conditions | Q46942610 | ||
| Age-related changes in the 20S and 26S proteasome activities in the liver of male F344 rats | Q47847864 | ||
| Activation of the proteasome during Xenopus egg activation implies a link between proteasome activation and intracellular calcium release | Q49022344 | ||
| Cardioprotection of exercise preconditioning involving heat shock protein 70 and concurrent autophagy: a potential chaperone-assisted selective macroautophagy effect. | Q51280141 | ||
| Reduced autophagy leads to an impaired ferritin turnover in senescent fibroblasts. | Q51358844 | ||
| Thymoproteasome shapes immunocompetent repertoire of CD8+ T cells. | Q53350619 | ||
| PARP-1: a new player in the asthma field? | Q53830448 | ||
| Altered dynamics of the lysosomal receptor for chaperone-mediated autophagy with age. | Q54557545 | ||
| The Lysosome | Q55037468 | ||
| Lipofuscin inhibits the proteasome by binding to surface motifs | Q59240639 | ||
| Protein oxidation and degradation during cellular senescence of human BJ fibroblasts: part II—aging of nondividing cells | Q60284685 | ||
| Proteasome β-type subunits: unequal roles of propeptides in core particle maturation and a hierarchy of active site function | Q60656421 | ||
| Age-related differences in oxidative protein-damage in young and senescent fibroblasts | Q60705157 | ||
| Human erythrocyte contains a factor that stimulates the peptidase activities of multicatalytic proteinase complex | Q67925446 | ||
| Proteasome activator PA28 and its interaction with 20 S proteasomes | Q71053872 | ||
| Fibroblast cultures from healthy centenarians have an active proteasome | Q73128693 | ||
| Hydrogen peroxide-induced structural alterations of RNAse A | Q73294198 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International | Q24082749 |
| P921 | main subject | proteostasis | Q2892805 |
| human ageing | Q332154 | ||
| oxidative stress | Q898814 | ||
| P304 | page(s) | 550-567 | |
| P577 | publication date | 2017-07-12 | |
| 2017-10-01 | |||
| P1433 | published in | Redox Biology | Q27724751 |
| P1476 | title | Proteostasis, oxidative stress and aging | |
| P478 | volume | 13 |
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