Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells

scientific article

Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/HMG/DDP558
P932PMC publication ID2816615
P698PubMed publication ID20015958
P5875ResearchGate publication ID40693340

P2093author name stringAndrew R Hoffman
An H Nguyen
Thanh H Vu
P2860cites workParental imprinting of the mouse H19 geneQ22122365
Interchromosomal associations between alternatively expressed lociQ22122480
CTCF binding at the H19 imprinting control region mediates maternally inherited higher-order chromatin conformation to restrict enhancer access to Igf2Q24295238
CTCF: master weaver of the genomeQ24621388
Methylation of a CTCF-dependent boundary controls imprinted expression of the Igf2 geneQ28145754
CTCF mediates methylation-sensitive enhancer-blocking activity at the H19/Igf2 locusQ28145756
Looping and interaction between hypersensitive sites in the active beta-globin locusQ28198196
Capturing chromosome conformationQ28201750
Chromosome Conformation Capture Carbon Copy (5C): a massively parallel solution for mapping interactions between genomic elementsQ28262061
Disruption of imprinting caused by deletion of the H19 gene region in miceQ28287765
Loss of silent-chromatin looping and impaired imprinting of DLX5 in Rett syndromeQ28592236
Physical linkage of two mammalian imprinted genes, H19 and insulin-like growth factor 2Q31158518
Chromatin conformation signatures of cellular differentiationQ33431476
Mapping networks of physical interactions between genomic elements using 5C technologyQ34578862
Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancerQ34620502
Correction of aberrant imprinting of IGF2 in human tumors by nuclear transfer-induced epigenetic reprogrammingQ35130964
Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switchingQ35194604
Analysis of the H19ICR insulatorQ35856849
Coregulated human globin genes are frequently in spatial proximity when activeQ36116796
Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor riskQ36693375
A complex deoxyribonucleic acid looping configuration associated with the silencing of the maternal Igf2 alleleQ36710170
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancerQ36835706
Three-dimensional conformation at the H19/Igf2 locus supports a model of enhancer trackingQ36876294
CTCF regulates allelic expression of Igf2 by orchestrating a promoter-polycomb repressive complex 2 intrachromosomal loopQ36959918
Glucocorticoid receptor activation of the Ciz1-Lcn2 locus by long range interactionsQ37112229
The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencingQ37201459
Increased expression of the insulin-like growth factor-II gene in Wilms' tumor is not dependent on loss of genomic imprinting or loss of heterozygosityQ38351907
Transient homologous chromosome pairing marks the onset of X inactivationQ40327289
Global loss of imprinting leads to widespread tumorigenesis in adult miceQ40361864
Large scale mapping of methylcytosines in CTCF-binding sites in the human H19 promoter and aberrant hypomethylation in human bladder cancerQ40766020
Visualization of looping involving the immunoglobulin heavy-chain locus in developing B cellsQ40974584
Symmetric and asymmetric DNA methylation in the human IGF2-H19 imprinted regionQ41726237
Interaction between differentially methylated regions partitions the imprinted genes Igf2 and H19 into parent-specific chromatin loopsQ42632085
Disruption of an imprinted gene cluster by a targeted chromosomal translocation in miceQ42658164
CTCF mediates interchromosomal colocalization between Igf2/H19 and Wsb1/Nf1.Q43651581
A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesisQ46050836
Promoter-specific imprinting of the human insulin-like growth factor-II geneQ46095293
Mouse/human sequence divergence in a region with a paternal-specific methylation imprint at the human H19 locusQ48061527
Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human.Q48096674
Transient colocalization of X-inactivation centres accompanies the initiation of X inactivation.Q51822086
Altered gene expression and methylation of the human chromosome 11 imprinted region in small for gestational age (SGA) placentae.Q51954217
Relaxation of imprinted genes in human cancer.Q52545355
Altered body composition and increased frequency of diverse malignancies in insulin-like growth factor-II transgenic mice.Q53472225
Parental imprinting of the mouse insulin-like growth factor II gene.Q55052428
Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumourQ59088779
IGF-II serum levels are normal in children with Silver-Russell syndrome who frequently carry epimutations at the IGF2 locus.Q64970681
IGF2 is parentally imprinted during human embryogenesis and in the Beckwith-Wiedemann syndromeQ70765937
Parental genomic imprinting of the human IGF2 geneQ72222239
Loss of IGF2 imprinting: a potential marker of colorectal cancer riskQ73128690
Imprinting status of 11p15 genes in Beckwith-Wiedemann syndrome patients with CDKN1C mutationsQ74051048
Loss of imprinting of insulin-like growth factor-II in Wilms' tumor commonly involves altered methylation but not mutations of CTCF or its binding siteQ74114381
Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instabilityQ77534962
Epigenetic regulation of Ifng expressionQ80501241
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in miceQ81441297
Molecular biology. Managing associations between different chromosomesQ83154060
P433issue5
P304page(s)901-919
P577publication date2009-12-16
P1433published inHuman Molecular GeneticsQ2720965
P1476titleLoss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cells
P478volume19

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cites work (P2860)
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