Genome-wide approaches for cancer gene discovery.

scientific article

Genome-wide approaches for cancer gene discovery. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.TIBTECH.2011.06.003
P932PMC publication ID3195896
P698PubMed publication ID21757246
P5875ResearchGate publication ID51493053

P50authorMatteo ForloniQ56670648
P2093author name stringNarendra Wajapeyee
Paul M Lizardi
P2860cites workTranscriptional Regulatory Elements in the Human GenomeQ22065387
A large-scale RNAi screen in human cells identifies new components of the p53 pathwayQ24319883
Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genesQ24540025
Frequent mutation of BAP1 in metastasizing uveal melanomasQ24601069
Core signaling pathways in human pancreatic cancers revealed by global genomic analysesQ24606006
Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usageQ24616834
A comprehensive catalogue of somatic mutations from a human cancer genomeQ24628532
Recurring mutations found by sequencing an acute myeloid leukemia genomeQ24634204
DNA sequencing of a cytogenetically normal acute myeloid leukaemia genomeQ24644436
A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogeneQ24647664
Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1Q24651548
Comprehensive genomic characterization defines human glioblastoma genes and core pathwaysQ24656128
Pyruvate kinase M2 is a phosphotyrosine-binding proteinQ27650067
Sequencing technologies - the next generationQ27860568
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegansQ27860867
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cellsQ27860926
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancerQ27860985
Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysisQ28119086
Lessons from hereditary colorectal cancerQ28131788
Comprehensive mapping of long-range interactions reveals folding principles of the human genomeQ28131819
Capturing chromosome conformationQ28201750
Post-transcriptional gene silencing by double-stranded RNAQ28205087
Pyruvate kinase type M2 and its role in tumor growth and spreadingQ28252131
The concept of synthetic lethality in the context of anticancer therapyQ28268061
Second-generation shRNA libraries covering the mouse and human genomesQ28275183
The cancer epigenome--components and functional correlatesQ28278109
The epigenomics of cancerQ28289975
Frequent mutations of chromatin remodeling gene ARID1A in ovarian clear cell carcinomaQ28292742
Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhingedQ28297381
p53 mutations in human cancersQ28302973
An oestrogen-receptor-α-bound human chromatin interactomeQ29541719
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growthQ29547680
A global view of gene activity and alternative splicing by deep sequencing of the human transcriptomeQ29615877
Genome-wide analysis of mammalian promoter architecture and evolutionQ29616717
Principles of cancer therapy: oncogene and non-oncogene addictionQ29616779
Integrative genomic profiling of human prostate cancerQ29619905
Genome-wide in situ exon capture for selective resequencingQ30004193
Advances in understanding cancer genomes through second-generation sequencingQ30014827
Massively parallel exon capture and library-free resequencing across 16 genomesQ30860233
Genome wide identification and classification of alternative splicing based on EST dataQ30926705
Increasing alternative promoter repertories is positively associated with differential expression and disease susceptibilityQ30979181
A resource for large-scale RNA-interference-based screens in mammals.Q33200135
CAGE: cap analysis of gene expressionQ33234345
Lessons from Nature: microRNA-based shRNA librariesQ33255058
Integrative genomic approaches identify IKBKE as a breast cancer oncogeneQ33287979
Cancer proliferation gene discovery through functional genomics.Q33317743
Genome-wide analysis of alternative promoters of human genes using a custom promoter tiling arrayQ33355172
Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE dataQ33485579
Loss of IGF2 imprinting is associated with abrogation of long-range intrachromosomal interactions in human cancer cellsQ33630697
Making sense of cancer genomic dataQ33846850
A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implicationsQ33900952
Target-enrichment strategies for next-generation sequencingQ34095491
The mutation spectrum revealed by paired genome sequences from a lung cancer patientQ34117627
Genome-wide mapping of RNA Pol-II promoter usage in mouse tissues by ChIP-seq.Q34138138
An oncogenomics-based in vivo RNAi screen identifies tumor suppressors in liver cancerQ34345765
A global view of genomic information--moving beyond the gene and the master regulatorQ35014896
Genome-wide mapping and analysis of active promoters in mouse embryonic stem cells and adult organsQ36259297
Mammalian RNA polymerase II core promoters: insights from genome-wide studiesQ36814333
High-resolution mapping of copy-number alterations with massively parallel sequencingQ37072451
The functional consequences of alternative promoter use in mammalian genomesQ37105466
The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancerQ37390854
Epigenetic silencing of the RASSF1A tumor suppressor gene through HOXB3-mediated induction of DNMT3B expressionQ37419612
Rapid creation and quantitative monitoring of high coverage shRNA librariesQ37440284
Alternative promoters in developmental gene expressionQ38186018
Integrating genetic approaches into the discovery of anticancer drugsQ38555487
Prediction of alternative isoforms from exon expression levels in RNA-Seq experimentsQ39740593
Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cellsQ39843809
A genome-wide shRNA screen identifies GAS1 as a novel melanoma metastasis suppressor geneQ39921794
Oncogenic BRAF induces senescence and apoptosis through pathways mediated by the secreted protein IGFBP7.Q40014237
Profiling essential genes in human mammary cells by multiplex RNAi screeningQ40018285
An elaborate pathway required for Ras-mediated epigenetic silencingQ40062561
Regulation of gene expression by alternative promotersQ40996777
Characterization and predictive discovery of evolutionarily conserved mammalian alternative promotersQ42277431
Predicting the future for people with lung cancerQ42878612
p53: a frequent target for genetic abnormalities in lung cancer.Q52486321
Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.Q52904089
Social and Economic Factors in the Choice of Lung Cancer TreatmentQ59188077
P433issue11
P921main subjectgene discoveryQ129262352
P304page(s)558-568
P577publication date2011-07-13
P1433published inTrends in BiotechnologyQ2451465
P1476titleGenome-wide approaches for cancer gene discovery
P478volume29

Reverse relations

cites work (P2860)
Q53211105Alternative splicing within the Wnt signaling pathway: role in cancer development.
Q42321079Clinical, molecular- and cytogenetic analysis of a case of severe radio-sensitivity
Q39070689Identification and characterization of human MIBP1 gene in glioma cell differentiation
Q31096031Identification of novel direct targets of Drosophila Sine oculis and Eyes absent by integration of genome-wide data sets
Q48938509Large-Scale RNA Interference Screening to Identify Transcriptional Regulators of a Tumor Suppressor Gene
Q64069891Matrix Metalloproteinase 11 Is a Potential Therapeutic Target in Lung Adenocarcinoma
Q38958932Mislocalization-related disease gene discovery using gene expression based computational protein localization prediction
Q35671355Multiple signatures of a disease in potential biomarker space: Getting the signatures consensus and identification of novel biomarkers
Q40467056The epigenetic landscape of Alu repeats delineates the structural and functional genomic architecture of colon cancer cells.
Q50356845Transcriptional Analysis-Based Integrative Genomics Approach to Identify Tumor-Promoting Metabolic Genes

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