| scholarly article | Q13442814 |
| P50 | author | Jamie Vandenberg | Q42353728 |
| Dmitry Shishmarev | Q47130446 | ||
| Philip William Kuchel | Q67842175 | ||
| P2093 | author name string | Chai Ann Ng | |
| Matthew D Perry | |||
| Kevin Phan | |||
| Erikka David | |||
| P2860 | cites work | Rescue of aberrant gating by a genetically encoded PAS (Per-Arnt-Sim) domain in several long QT syndrome mutant human ether-á-go-go-related gene potassium channels | Q24301043 |
| A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel | Q24316252 | ||
| A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome | Q24316980 | ||
| The inward rectification mechanism of the HERG cardiac potassium channel | Q24320034 | ||
| Structure of the TRPA1 ion channel suggests regulatory mechanisms | Q24336461 | ||
| A recombinant N-terminal domain fully restores deactivation gating in N-truncated and long QT syndrome mutant hERG potassium channels | Q24655800 | ||
| Cryo-electron microscopy structure of the TRPV2 ion channel | Q27310168 | ||
| Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment | Q27649044 | ||
| Structure of the TRPV1 ion channel determined by electron cryo-microscopy | Q27680759 | ||
| Structure of the voltage-gated K⁺ channel Eag1 reveals an alternative voltage sensing mechanism | Q27727293 | ||
| Crystal structure and functional analysis of the HERG potassium channel N terminus: a eukaryotic PAS domain | Q27766251 | ||
| SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling | Q27860614 | ||
| The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling | Q27860637 | ||
| Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2 | Q28145423 | ||
| Two separate interfaces between the voltage sensor and pore are required for the function of voltage-dependent K(+) channels | Q28474961 | ||
| Crystal structure of the epithelial calcium channel TRPV6 | Q28568023 | ||
| A two-dimensional nuclear Overhauser enhancement (2D NOE) experiment for the elucidation of complete proton-proton cross-relaxation networks in biological macromolecules | Q29616473 | ||
| Protein structure homology modeling using SWISS-MODEL workspace. | Q30374281 | ||
| Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel | Q33147394 | ||
| Combined gating and trafficking defect in Kv11.1 manifests as a malignant long QT syndrome phenotype in a large Danish p.F29L founder family. | Q33166274 | ||
| S1 constrains S4 in the voltage sensor domain of Kv7.1 K+ channels | Q33327357 | ||
| Fluorescence-tracking of activation gating in human ERG channels reveals rapid S4 movement and slow pore opening | Q33595798 | ||
| Genotype-phenotype aspects of type 2 long QT syndrome | Q33598557 | ||
| Cryo-EM structure of the open high-conductance Ca2+-activated K+ channel | Q33882532 | ||
| LQTS gene LOVD database | Q34135397 | ||
| Mutating a critical lysine in ShK toxin alters its binding configuration in the pore-vestibule region of the voltage-gated potassium channel, Kv1.3. | Q34152433 | ||
| Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels. | Q34170800 | ||
| HERG channel (dys)function revealed by dynamic action potential clamp technique | Q34188575 | ||
| Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel | Q34998277 | ||
| The lipid-protein interface of a Shaker K(+) channel | Q35834786 | ||
| Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels | Q36209603 | ||
| A role for the S0 transmembrane segment in voltage-dependent gating of BK channels | Q36295991 | ||
| Fast inactivation causes rectification of the IKr channel | Q36411776 | ||
| Negative charges in the transmembrane domains of the HERG K channel are involved in the activation- and deactivation-gating processes | Q36412430 | ||
| Helical structure and packing orientation of the S2 segment in the Shaker K+ channel | Q36420402 | ||
| Dynamic control of deactivation gating by a soluble amino-terminal domain in HERG K(+) channels | Q36442897 | ||
| Gating charges in the activation and inactivation processes of the HERG channel | Q36445757 | ||
| Intermediate state trapping of a voltage sensor | Q36446395 | ||
| Mechanism of loss of Kv11.1 K+ current in mutant T421M-Kv11.1-expressing rat ventricular myocytes: interaction of trafficking and gating | Q36489344 | ||
| Nonsense mutations in hERG cause a decrease in mutant mRNA transcripts by nonsense-mediated mRNA decay in human long-QT syndrome | Q36648043 | ||
| Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating | Q36779531 | ||
| Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel | Q36949874 | ||
| Direct interaction of eag domains and cyclic nucleotide-binding homology domains regulate deactivation gating in hERG channels | Q37209213 | ||
| A functional Kv1.2-hERG chimaeric channel expressed in Pichia pastoris | Q37604013 | ||
| Voltage-dependent gating of HERG potassium channels | Q38010173 | ||
| hERG K(+) channels: structure, function, and clinical significance | Q38044402 | ||
| Eag Domains Regulate LQT Mutant hERG Channels in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes | Q38881012 | ||
| Large-scale mutational analysis of Kv11.1 reveals molecular insights into type 2 long QT syndrome | Q38938416 | ||
| Not all hERG pore domain mutations have a severe phenotype: G584S has an inactivation gating defect with mild phenotype compared to G572S, which has a dominant negative trafficking defect and a severe phenotype | Q39843866 | ||
| Rescue of protein expression defects may not be enough to abolish the pro-arrhythmic phenotype of long QT type 2 mutations | Q39935694 | ||
| Most LQT2 mutations reduce Kv11.1 (hERG) current by a class 2 (trafficking-deficient) mechanism | Q40326013 | ||
| Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway. | Q40448063 | ||
| Interaction between the Linker, Pre-S1, and TRP Domains Determines Folding, Assembly, and Trafficking of TRPV Channels | Q40767093 | ||
| Structural basis for gating the high-conductance Ca2+-activated K+ channel | Q41035015 | ||
| Electrostatic interactions of S4 voltage sensor in shaker K+ channel | Q41674764 | ||
| Interactions between S4-S5 linker and S6 transmembrane domain modulate gating of HERG K+ channels | Q42670847 | ||
| Identification of protein surfaces by NMR measurements with a pramagnetic Gd(III) chelate | Q43855230 | ||
| Proline kinks in transmembrane alpha-helices | Q44605716 | ||
| Interactions between voltage sensor and pore domains in a hERG K+ channel model from molecular simulations and the effects of a voltage sensor mutation. | Q44676105 | ||
| Interactions between charged residues in the transmembrane segments of the voltage-sensing domain in the hERG channel | Q44918225 | ||
| Voltage sensor of Kv1.2: structural basis of electromechanical coupling | Q46588794 | ||
| Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed | Q46705938 | ||
| Cooperative interactions between R531 and acidic residues in the voltage sensing module of hERG1 channels | Q46798464 | ||
| A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel. | Q48896326 | ||
| Long QT syndrome-associated mutations in the Per-Arnt-Sim (PAS) domain of HERG potassium channels accelerate channel deactivation. | Q48921379 | ||
| Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions. | Q50950249 | ||
| Temperature dependence of human ether-a-go-go-related gene K+ currents. | Q51810570 | ||
| Effects of premature stimulation on HERG K(+) channels | Q77355883 | ||
| Mapping the sequence of conformational changes underlying selectivity filter gating in the K(v)11.1 potassium channel | Q82951867 | ||
| Functional interactions between residues in the S1, S4, and S5 domains of Kv2.1. | Q83761306 | ||
| P433 | issue | 18 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Potassium voltage-gated channel subfamily H member 2 | Q905000 |
| voltage-gated potassium channel activity | Q14593999 | ||
| P304 | page(s) | 7688-7705 | |
| P577 | publication date | 2017-03-09 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The S1 helix critically regulates the finely tuned gating of Kv11.1 channels | |
| P478 | volume | 292 |
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