Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation

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Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1021981351
P356DOI10.1186/1476-4598-9-1
P932PMC publication ID2818691
P698PubMed publication ID20051109
P5875ResearchGate publication ID40849962

P2093author name stringLawrence S Young
Jianyong Shao
John D O'Neil
John R Arrand
Christopher W Dawson
Thomas J Owen
Chunfang Hu
Kathryn L Date
Robert Valentine
Khilan M Shah
Sonia P Maia
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Termination of NF-kappaB activity through a gammaherpesvirus protein that assembles an EC5S ubiquitin-ligaseQ24309461
Inhibition of IkappaB kinase by vaccinia virus virulence factor B14Q24312867
Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic miceQ24562912
Activation of nuclear factor-kappaB p50 homodimer/Bcl-3 complexes in nasopharyngeal carcinomaQ28191706
HAUSP/USP7 as an Epstein-Barr virus targetQ28288651
Epstein-Barr virus nuclear antigen 1 does not cause lymphoma in C57BL/6J miceQ28594944
Shared principles in NF-kappaB signalingQ29547234
Complementation Cloning of NEMO, a Component of the IκB Kinase Complex Essential for NF-κB ActivationQ29617419
EC5S ubiquitin complex is recruited by KSHV latent antigen LANA for degradation of the VHL and p53 tumor suppressorsQ33261811
Modulation of cellular and viral gene expression by the latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirusQ33835021
Epstein–Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growthQ33953070
Epstein-Barr virus and oncogenesis: from latent genes to tumoursQ34221194
Separation of the DNA replication, segregation, and transcriptional activation functions of Epstein-Barr nuclear antigen 1.Q34332147
Epstein-Barr virus in the pathogenesis of NPC.Q35008870
NF-kappaB and virus infection: who controls whomQ35139535
Viral appropriation of apoptotic and NF-kappaB signaling pathwaysQ35719506
Epstein-Barr virus induction of recombinase-activating genes RAG1 and RAG2Q35852995
Alterations in NF-κB function in transgenic epithelial tissue demonstrate a growth inhibitory role for NF-κBQ35913517
NF-kappaB and cancer: mechanisms and targetsQ36468005
Hypoxia-regulated carbonic anhydrase IX expression is associated with poor survival in patients with invasive breast cancer.Q36610569
The Epstein-Barr virus nuclear protein 1 promoter active in type I latency is autoregulatedQ36699468
Expression of the Epstein-Barr virus-encoded Epstein-Barr virus nuclear antigen 1 in Hodgkin's lymphoma cells mediates Up-regulation of CCL20 and the migration of regulatory T cellsQ36734903
Identifying sites bound by Epstein-Barr virus nuclear antigen 1 (EBNA1) in the human genome: defining a position-weighted matrix to predict sites bound by EBNA1 in viral genomesQ37127891
Epstein-Barr virus-encoded LMP2A regulates viral and cellular gene expression by modulation of the NF-kappaB transcription factor pathway.Q37595549
Epstein-Barr virus small RNAs potentiate tumorigenicity of Burkitt lymphoma cells independently of an effect on apoptosisQ39539644
Expression of epstein-barr virus nuclear antigen 1 is associated with enhanced expression of CD25 in the Hodgkin cell line L428.Q39549562
Mapping EBNA-1 domains involved in binding to metaphase chromosomes.Q39550682
Epstein-Barr Virus Contributes to the Malignant Phenotype and to Apoptosis Resistance in Burkitt’s Lymphoma Cell Line AkataQ39582149
Epstein-Barr virus-encoded EBNA1 modulates the AP-1 transcription factor pathway in nasopharyngeal carcinoma cells and enhances angiogenesis in vitroQ39927855
Phosphatidylcholine hydrolysis activates NF-kappa B and increases human immunodeficiency virus replication in human monocytes and T lymphocytes.Q40047929
Interplay between E-box and NF-kappaB in regulation of A20 gene by DRB sensitivity-inducing factor (DSIF).Q40061994
Epstein-Barr virus-encoded EBNA1 regulates cellular gene transcription and modulates the STAT1 and TGFbeta signaling pathwaysQ40135893
C/EBP beta blocks p65 phosphorylation and thereby NF-kappa B-mediated transcription in TNF-tolerant cellsQ40265408
Immortalized embryonic mouse fibroblasts lacking the RelA subunit of transcription factor NF-kappaB have a malignantly transformed phenotypeQ40736254
Nuclear factor kappaB subunits induce epithelial cell growth arrestQ41756058
NF-kappaB blockade and oncogenic Ras trigger invasive human epidermal neoplasia.Q45982548
Reactive nitrogen species-dependent DNA damage in EBV-associated nasopharyngeal carcinoma: the relation to STAT3 activation and EGFR expressionQ46728299
Establishment and characterization of three transplantable EBV-containing nasopharyngeal carcinomasQ70061763
Profile of cytokine expression in nasopharyngeal carcinomas: a distinct expression of interleukin 1 in tumor and CD4+ T cellsQ77304089
P921main subjectEpstein–Barr virusQ6900
phosphorylationQ242736
NF-κBQ411114
P304page(s)1
P577publication date2010-01-05
P1433published inMolecular CancerQ15724585
P1476titleEpstein-Barr virus-encoded EBNA1 inhibits the canonical NF-kappaB pathway in carcinoma cells by inhibiting IKK phosphorylation
P478volume9

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cites work (P2860)
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