Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth

scientific article

Epstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth is …
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scholarly articleQ13442814

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P819ADS bibcode2001PNAS...9815233K
P356DOI10.1073/PNAS.211556598
P932PMC publication ID65012
P698PubMed publication ID11734622
P5875ResearchGate publication ID11621018

P50authorElliott D. KieffQ43399614
P2093author name stringM S Kang
S C Hung
P2860cites workNF-kappa B inhibition causes spontaneous apoptosis in Epstein-Barr virus-transformed lymphoblastoid cellsQ22254088
Structure and coding content of CST (BART) family RNAs of Epstein-Barr virusQ24524755
An Epstein-Barr virus protein interacts with NotchQ24529019
Expression of Epstein-Barr virus nuclear antigen-1 induces B cell neoplasia in transgenic miceQ24562912
The cellular proteins that bind specifically to the Epstein-Barr virus origin of plasmid DNA replication belong to a gene familyQ24563778
Binding of basal transcription factor TFIIH to the acidic activation domains of VP16 and p53Q24609153
Enhancement of hepatitis C virus replication by Epstein-Barr virus-encoded nuclear antigen 1.Q27470145
The 2.2 A structure of a permanganate-sensitive DNA site bound by the Epstein-Barr virus origin binding protein, EBNA1Q27766425
Advanced mammalian gene transfer: high titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell lineQ29547239
GAL4-VP16 is an unusually potent transcriptional activatorQ29616453
P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein-Barr virus.Q33292267
Functional analyses of the EBNA1 origin DNA binding protein of Epstein-Barr virusQ33787020
An Epstein-Barr virus that expresses only the first 231 LMP1 amino acids efficiently initiates primary B-lymphocyte growth transformationQ33825713
Activator-dependent transcription from chromatin in vitro involving targeted histone acetylation by p300.Q33921258
Maintenance of Epstein-Barr virus (EBV) oriP-based episomes requires EBV-encoded nuclear antigen-1 chromosome-binding domains, which can be replaced by high-mobility group-I or histone H1.Q34107917
Stable replication of plasmids derived from Epstein-Barr virus in various mammalian cellsQ34564031
The Epstein-Barr virus nuclear protein 2 acidic domain can interact with TFIIB, TAF40, and RPA70 but not with TATA-binding protein.Q35830605
An EBNA-1-dependent enhancer acts from a distance of 10 kilobase pairs to increase expression of the Epstein-Barr virus LMP geneQ35838226
Epstein-Barr virus induction of recombinase-activating genes RAG1 and RAG2Q35852995
Epstein-Barr virus RNA. V. Viral RNA in a restringently infected, growth-transformed cell lineQ36507642
Effect of number and position of EBNA-1 binding sites in Epstein-Barr virus oriP on the sites of initiation, barrier formation, and termination of replicationQ36644839
Functional domains of Epstein-Barr virus nuclear antigen EBNA-1.Q36682530
Definition of the sequence requirements for binding of the EBNA-1 protein to its palindromic target sites in Epstein-Barr virus DNAQ36806138
Multiple EBNA1-binding sites are required to form an EBNA1-dependent enhancer and to activate a minimal replicative origin within oriP of Epstein-Barr virus.Q36828339
A putative origin of replication of plasmids derived from Epstein-Barr virus is composed of two cis-acting componentsQ36891387
trans activation of an Epstein-Barr viral transcriptional enhancer by the Epstein-Barr viral nuclear antigen 1.Q36899288
Epstein-Barr virus nuclear protein 2 interacts with p300, CBP, and PCAF histone acetyltransferases in activation of the LMP1 promoterQ37156071
Inhibition of proteasomal degradation by the gly-Ala repeat of Epstein-Barr virus is influenced by the length of the repeat and the strength of the degradation signalQ37225439
Chromosome site for Epstein-Barr virus DNA in a Burkitt tumor cell line and in lymphocytes growth-transformed in vitroQ37608005
Selective inhibition of activated but not basal transcription by the acidic activation domain of VP16: evidence for transcriptional adaptorsQ38340343
Expression of epstein-barr virus nuclear antigen 1 is associated with enhanced expression of CD25 in the Hodgkin cell line L428.Q39549562
Genetic evidence that EBNA-1 is needed for efficient, stable latent infection by Epstein-Barr virusQ39549892
Mapping EBNA-1 domains involved in binding to metaphase chromosomes.Q39550682
Reconstitution of Epstein-Barr virus-based plasmid partitioning in budding yeastQ39696990
Regulation of EBNA gene transcription in lymphoblastoid cell lines: characterization of sequences downstream of BCR2 (Cp).Q39877574
Dominant-negative inhibitors of EBNA-1 of Epstein-Barr virus.Q39878386
The prototypical Epstein-Barr virus-transformed lymphoblastoid cell line IB4 is an unusual variant containing integrated but no episomal viral DNAQ40067397
Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis.Q40139467
The expression pattern of Epstein-Barr virus latent genes in vivo is dependent upon the differentiation stage of the infected B cellQ40843575
Tet repressor-based system for regulated gene expression in eukaryotic cells: principles and advancesQ40846822
Cytostatic effect of Epstein-Barr virus latent membrane protein-1 analyzed using tetracycline-regulated expression in B cell linesQ41172143
Upstream basal promoter element important for exclusive RNA polymerase III transcription of the EBER 2 geneQ42133835
Expression of Epstein-Barr virus BamHI-A rightward transcripts in latently infected B cells from peripheral blood.Q42599854
Sequence-specific DNA binding of the Epstein-Barr virus nuclear antigen (EBNA-1) to clustered sites in the plasmid maintenance regionQ44286183
Persistence of the Entire Epstein-Barr Virus Genome Integrated into Human Lymphocyte DNAQ45807117
Novel hypotheses for the roles of EBNA-1 and BHRF1 in EBV-related cancersQ71195340
P4510describes a project that usesImageQuantQ112270642
P433issue26
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
P304page(s)15233-15238
P577publication date2001-12-04
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleEpstein-Barr virus nuclear antigen 1 activates transcription from episomal but not integrated DNA and does not alter lymphocyte growth
P478volume98

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cites work (P2860)
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Q42681249bcl-xL and RAG genes are induced and the response to IL-2 enhanced in EmuEBNA-1 transgenic mouse lymphocytes.