Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications

scientific article

Regulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.4049/JIMMUNOL.1400498
P932PMC publication ID4030688
P698PubMed publication ID24837152
P5875ResearchGate publication ID262423435

P50authorJeremy KinderQ42760645
Sing Sing WayQ56427685
P2093author name stringAmy M Valent
Dayna R Clark
James M Ertelt
Lijun Xin
Tony T Jiang
Vandana Chaturvedi
P2860cites workMale fetal progenitor cells persist in maternal blood for as long as 27 years postpartumQ24567463
A critical role for murine complement regulator crry in fetomaternal toleranceQ28594227
Extrathymic generation of regulatory T cells in placental mammals mitigates maternal-fetal conflictQ28728365
CTLA-4 control over Foxp3+ regulatory T cell functionQ29619413
Regulatory T cells: mechanisms of differentiation and functionQ29620731
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceQ29622850
Minor histocompatibility antigens and the maternal immune response to the fetus during pregnancyQ33723635
Maternal CD4⁺ and CD8⁺ T cell tolerance towards a fetal minor histocompatibility antigen in T cell receptor transgenic miceQ33826277
Pregnancy induces a fetal antigen-specific maternal T regulatory cell response that contributes to toleranceQ33927418
Self-specific memory regulatory T cells protect embryos at implantation in miceQ33936068
Reciprocal interactions of the intestinal microbiota and immune system.Q34033579
Phenotypic characterization of regulatory T cells in the human decidua.Q34313811
Normal human pregnancy is associated with an elevation in the immune suppressive CD25+ CD4+ regulatory T-cell subset.Q34314847
RETRACTED: Pregnancy-associated exosomes and their modulation of T cell signalingQ34486229
Acquisition and presentation of follicular dendritic cell-bound antigen by lymph node-resident dendritic cellsQ34501458
Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfacesQ34590015
Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell developmentQ34597933
The inflammatory response to cell deathQ34718276
Abnormal T-cell reactivity against paternal antigens in spontaneous abortion: adoptive transfer of pregnancy-induced CD4+CD25+ T regulatory cells prevents fetal rejection in a murine abortion modelQ35083726
Foxp3(+) regulatory T cell expansion required for sustaining pregnancy compromises host defense against prenatal bacterial pathogensQ35117262
Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into Th17 cellsQ35164020
Comparative Genomics Reveals Key Gain-of-Function Events in Foxp3 during Regulatory T Cell EvolutionQ35949449
Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cellsQ36228688
Pregnancy imprints regulatory memory that sustains anergy to fetal antigenQ36300965
Progesterone suppresses the mTOR pathway and promotes generation of induced regulatory T cells with increased stabilityQ36890286
Chemokine gene silencing in decidual stromal cells limits T cell access to the maternal-fetal interfaceQ37056152
Dendritic cell entrapment within the pregnant uterus inhibits immune surveillance of the maternal/fetal interface in miceQ37241426
Regulatory T cells and the immune pathogenesis of prenatal infectionQ37248735
Maternal morbidity and mortality associated with interpregnancy interval: cross sectional studyQ37364609
Maternal PD-1 regulates accumulation of fetal antigen-specific CD8+ T cells in pregnancyQ37393109
Different routes of bacterial infection induce long-lived TH1 memory cells and short-lived TH17 cellsQ37483184
Embryonic trophoblasts induce decidual regulatory T cell differentiation and maternal-fetal tolerance through thymic stromal lymphopoietin instructing dendritic cellsQ37571574
Regulatory T cells: how do they suppress immune responses?Q37593768
Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective.Q37638204
Cutting edge: committed Th1 CD4+ T cell differentiation blocks pregnancy-induced Foxp3 expression with antigen-specific fetal lossQ37678898
Pregnancy-induced maternal regulatory T cells, bona fide memory or maintenance by antigenic reminder from fetal cell microchimerism?Q37705079
Th1/Th2/Th17 and regulatory T-cell paradigm in pregnancyQ37747554
Phenotypical and functional specialization of FOXP3+ regulatory T cellsQ37832385
Foxp3(+) regulatory T cells, immune stimulation and host defence against infectionQ37972689
Selection of regulatory T cells in the thymusQ37982939
T cell tolerance and immunity to commensal bacteria.Q38011862
Seminal fluid and the generation of regulatory T cells for embryo implantation.Q38088289
Tumor necrosis factor-alpha, interleukin-6, and interleukin-10 levels are altered in preeclampsia: a systematic review and meta-analysis.Q38116097
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine productionQ40165347
Pregnancy-associated changes in peripheral blood lymphocyte subpopulations in normal Kuwaiti womenQ40673529
Preeclampsia: an excessive maternal inflammatory response to pregnancyQ40824430
Changing paternity and the risk of preeclampsia/eclampsia in the subsequent pregnancyQ41712736
A class I antigen, HLA-G, expressed in human trophoblastsQ41737375
Progesterone Increases Systemic and Local Uterine Proportions of CD4+CD25+ Treg Cells during Midterm Pregnancy in MiceQ42906422
Human CD4+ regulatory T cells express lower levels of the IL-7 receptor alpha chain (CD127), allowing consistent identification and sorting of live cellsQ43948313
PD-1 but not CTLA-4 blockage abrogates the protective effect of regulatory T cells in a pregnancy murine modelQ44516808
Cutting edge: estrogen drives expansion of the CD4+CD25+ regulatory T cell compartmentQ45007526
Evidence for a selective migration of fetus-specific CD4+CD25bright regulatory T cells from the peripheral blood to the decidua in human pregnancyQ45421356
Immunoactivation in preeclampsia: Vdelta2+ and regulatory T cells during the inflammatory stage of diseaseQ45660279
Systemic reduction of functionally suppressive CD4dimCD25highFoxp3+ Tregs in human second trimester pregnancy is induced by progesterone and 17beta-estradiol.Q45964915
Systemic increase in the ratio between Foxp3+ and IL-17-producing CD4+ T cells in healthy pregnancy but not in preeclampsiaQ46332630
Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memoryQ46347403
Enhanced FoxP3 expression and Treg cell function in pregnant and estrogen-treated miceQ46777414
Kinetics of regulatory T cells during murine pregnancyQ46903699
Preeclampsia is associated with lower percentages of regulatory T cells in maternal bloodQ47890265
Decidual and peripheral blood CD4+CD25+ regulatory T cells in early pregnancy subjects and spontaneous abortion casesQ48008881
Regulatory T cells are necessary for implantation and maintenance of early pregnancy but not late pregnancy in allogeneic mice.Q51567875
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13.Q51708862
Changes of CD4+CD25high regulatory T cells and FOXP3 expression in unexplained recurrent spontaneous abortion patients.Q51790350
CD4+CD25+ regulatory/suppressor T cells prevent allogeneic fetus rejection in mice.Q51838714
Decreased number of FoxP3+ regulatory T cells in preeclampsia.Q51960611
Activated T lymphocytes in pre-eclampsia.Q51974454
The Th2 cytokines IL-4 and IL-10 are not crucial for the completion of allogeneic pregnancy in mice.Q52132990
Pre-eclampsiaQ56019568
The CD4+CD25 bright regulatory T cells and CTLA-4 expression in peripheral and decidual lymphocytes are down-regulated in human miscarriageQ56899848
Pre-eclampsia is not associated with changes in the levels of regulatory T cells in peripheral bloodQ56902489
The Interval between Pregnancies and the Risk of PreeclampsiaQ57420054
Diphtheria toxin receptor–mediated conditional and targeted cell ablation in transgenic miceQ60017797
Characterization of regulatory T cells in decidua of miscarriage cases with abnormal or normal fetal chromosomal contentQ61839826
Decidual CD4+CD25+CD127dim/- regulatory T cells in patients with unexplained recurrent spontaneous miscarriageQ61840747
Altered Decidual DC-SIGN+ Antigen-Presenting Cells and Impaired Regulatory T-Cell Induction in PreeclampsiaQ61847203
Increased prevalence of T helper 17 (Th17) cells in peripheral blood and decidua in unexplained recurrent spontaneous abortion patients.Q64950160
Normal trophoblasts resist induction of class I HLAQ70332600
T cell awareness of paternal alloantigens during pregnancyQ71768391
Lymphocyte subpopulations in pregnancy complicated by hypertensionQ73093828
Regulatory T cells mediate maternal tolerance to the fetusQ75394803
Expansion of CD4+CD25+and FOXP3+ regulatory T cells during the follicular phase of the menstrual cycle: implications for human reproductionQ79718078
Proportion of peripheral blood and decidual CD4(+) CD25(bright) regulatory T cells in pre-eclampsiaQ80216688
Proportional change of CD4+CD25+ regulatory T cells in decidua and peripheral blood in unexplained recurrent spontaneous abortion patientsQ80418930
Fetal alloantigen is responsible for the expansion of the CD4(+)CD25(+) regulatory T cell pool during pregnancyQ80766981
A link between PDL1 and T regulatory cells in fetomaternal toleranceQ81386275
Distinct subsets of regulatory T cells during pregnancy: is the imbalance of these subsets involved in the pathogenesis of preeclampsia?Q82016278
Study on the Relationship Between Th17 Cells and Unexplained Recurrent Spontaneous AbortionQ82205254
Differential distribution of CD4(+)CD25(bright) and CD8(+)CD28(-) T-cells in decidua and maternal blood during human pregnancyQ82406065
Increased prevalence of IL-17-producing peripheral blood lymphocytes in pre-eclampsiaQ83391804
The predominance of Th17 lymphocytes and decreased number and function of Treg cells in preeclampsiaQ83523001
The frequency of peripheral blood CD4+ CD25high FoxP3+ and CD4+ CD25- FoxP3+ regulatory T cells in normal pregnancy and pre-eclampsiaQ83910661
IL-6 trans-signaling and the frequency of CD4+FOXP3+ cells in women with reproductive failureQ84374470
Term and preterm labor: decreased suppressive activity and changes in composition of the regulatory T-cell poolQ84507551
An imbalance in interleukin-17-producing T and Foxp3⁺ regulatory T cells in women with idiopathic recurrent pregnancy lossQ84957843
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)4949-4956
P577publication date2014-06-01
P1433published inJournal of ImmunologyQ3521441
P1476titleRegulatory T cells: new keys for further unlocking the enigma of fetal tolerance and pregnancy complications
P478volume192

Reverse relations

cites work (P2860)
Q57177752A historical review of blastocyst implantation research
Q33845963CXCL10 and IL-6: Markers of two different forms of intra-amniotic inflammation in preterm labor
Q35408974CXCR3 blockade protects against Listeria monocytogenes infection-induced fetal wastage
Q35908920Cross-Generational Reproductive Fitness Enforced by Microchimeric Maternal Cells.
Q50715033Differentiation of ICOS+ and ICOS- recent thymic emigrant regulatory T cells (RTE T regs) during normal pregnancy, pre-eclampsia and HELLP syndrome.
Q39269920Ectopic Trophoblast Allografts in the Horse Resist Destruction by Secondary Immune Responses
Q37337117Exosomes: The missing link between microchimerism and acquired tolerance?
Q40061417Fetal death: an extreme manifestation of maternal anti-fetal rejection
Q47910452Frontline Science: Myeloid-derived suppressor cells (MDSCs) facilitate maternal-fetal tolerance in mice
Q34502343Helminth infection, fecundity, and age of first pregnancy in women
Q90740831Human labour is associated with altered regulatory T cell function and maternal immune activation
Q57160415Immunological Basis for Recurrent Fetal Loss and Pregnancy Complications
Q47550799Immunological Tolerance, Pregnancy, and Preeclampsia: The Roles of Semen Microbes and the Father
Q38686693Immunological implications of pregnancy-induced microchimerism.
Q37425026InlP, a New Virulence Factor with Strong Placental Tropism
Q53914095Involvement of Clustered Genes in Mammalian Functions: Their Relation in a Rat Mutant Strain.
Q92952961Longitudinal profiling of human blood transcriptome in healthy and lupus pregnancy
Q95936637Maternal and fetal T cells in term pregnancy and preterm labor
Q52632153Maternal-fetal cross talk through cell-free fetal DNA, telomere shortening, microchimerism, and inflammation.
Q39400476Mechanistic Insight into Long Noncoding RNAs and the Placenta
Q34808663Microbes central to human reproduction
Q28081268Molecular Regulation of Parturition: The Role of the Decidual Clock
Q89533651Multiomic immune clockworks of pregnancy
Q64954875Myeloid-Derived Suppressor Cells: Not Only in Tumor Immunity.
Q37097734Patterns of Immune Regulation in Rhesus Macaque and Human Families
Q37420611Regulatory T cell memory
Q41136100Regulatory T-cell Subpopulations in Severe or Early-onset Preeclampsia
Q38637362Regulatory T-cells and preeclampsia: an overview of literature
Q57804787Schedule and magnitude of reproductive investment under immune trade-offs explains sex differences in immunity
Q99711563T Helper (Th) Cell Profiles in Pregnancy and Recurrent Pregnancy Losses: Th1/Th2/Th9/Th17/Th22/Tfh Cells
Q90720281TGFb1 suppresses the activation of distinct dNK subpopulations in preeclampsia
Q47889401The Complement System and Preeclampsia
Q38634374To serve and to protect: the role of decidual innate immune cells on human pregnancy
Q38721657What is wrong with the regulatory T cells and foetomaternal tolerance in women with recurrent miscarriages?

Search more.