| scholarly article | Q13442814 |
| P819 | ADS bibcode | 1988PNAS...85.7704S |
| P356 | DOI | 10.1073/PNAS.85.20.7704 |
| P932 | PMC publication ID | 282261 |
| P698 | PubMed publication ID | 2459714 |
| P5875 | ResearchGate publication ID | 20695849 |
| P2093 | author name string | Y C Lin | |
| J Stavnezer | |||
| R Sitia | |||
| L Berggren | |||
| E Severinson | |||
| G Radcliffe | |||
| J Nietupski | |||
| P2860 | cites work | Secondary genomic rearrangement events in pre-B cells: VHDJH replacement by a LINE-1 sequence and directed class switching | Q33880995 |
| Cloning of cDNA encoding the murine IgG1 induction factor by a novel strategy using SP6 promoter | Q34161873 | ||
| Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II. | Q34162731 | ||
| Number and evolutionary conservation of alpha- and beta-tubulin and cytoplasmic beta- and gamma-actin genes using specific cloned cDNA probes | Q34272920 | ||
| Cloning of mouse immunoglobulin epsilon gene and its location within the heavy chain gene cluster | Q35325120 | ||
| T cell-derived B cell differentiation factor(s). Effect on the isotype switch of murine B cells | Q36346260 | ||
| Clonal analysis of B cells induced to secrete IgG by T cell-derived lymphokine(s) | Q36349733 | ||
| Induction of immunoglobulin isotype switching in cultured I.29 B lymphoma cells. Characterization of the accompanying rearrangements of heavy chain genes | Q36349920 | ||
| Purification to homogeneity of B cell stimulating factor. A molecule that stimulates proliferation of multiple lymphokine-dependent cell lines | Q36351853 | ||
| Differential regulation of IgG1 and IgE synthesis by interleukin 4. | Q36354355 | ||
| Structure and expression of germ line immunoglobulin gamma 2b transcripts | Q36787710 | ||
| The role of helper T cell products in mouse B cell differentiation and isotype regulation | Q39485849 | ||
| Regulation of Ig Class Secretion by Soluble Products of Certain T-Cell Lines | Q40117394 | ||
| Directed Ig class switch recombination in activated murine B cells. | Q41341371 | ||
| Specificity of immunoglobulin heavy chain switch correlates with activity of germline heavy chain genes prior to switching. | Q42565372 | ||
| Reversibility of muscle differentiation in the absence of commitment: analysis of a myogenic cell line temperature-sensitive for commitment | Q42798649 | ||
| Differentiation in the murine B cell lymphoma I.29: individual mu + clones may be induced by lipopolysaccharide to both IgM secretion and isotype switching. | Q43419861 | ||
| Mitogen- and IL-4-regulated expression of germ-line Ig gamma 2b transcripts: evidence for directed heavy chain class switching | Q43475698 | ||
| Interleukin 5 and interleukin 4 produced by Peyer's patch T cells selectively enhance immunoglobulin A expression. | Q43580224 | ||
| Secretion of IgG1 induction factor by T cell clones and hybridomas | Q44387861 | ||
| C mu-containing transcripts initiate heterogeneously within the IgH enhancer region and contain a novel 5'-nontranslatable exon | Q44747778 | ||
| DNA sequence of the murine gamma 1 switch segment reveals novel structural elements | Q44949424 | ||
| I.29 lymphoma cells express a nonmutated VH gene before and after H chain switch. | Q46008607 | ||
| Recombination between immunoglobulin variable region gene segments is enhanced by transcription | Q59066787 | ||
| The role of IL-5 in IgA B cell differentiation | Q68092931 | ||
| A mouse T cell product that preferentially enhances IgA production. I. Biologic characterization | Q70041471 | ||
| Interferon-gamma and B cell stimulatory factor-1 reciprocally regulate Ig isotype production | Q70338857 | ||
| 5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains | Q71520598 | ||
| P433 | issue | 20 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 7704-7708 | |
| P577 | publication date | 1988-10-01 | |
| P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
| P1476 | title | Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes | |
| P478 | volume | 85 |
| Q36797954 | A B-cell-specific nuclear protein that binds to DNA sites 5' to immunoglobulin S alpha tandem repeats is regulated during differentiation |
| Q40873846 | A selective defect in IgG2b switching as a result of targeted mutation of the I gamma 2b promoter and exon |
| Q48162656 | A survey of protein-DNA interaction sites within the murine immunoglobulin heavy chain locus reveals a particularly complex pattern around the DQ52 element |
| Q38680202 | A transcriptional serenAID: the role of noncoding RNAs in class switch recombination |
| Q35082618 | Accessibility control and machinery of immunoglobulin class switch recombination |
| Q36561776 | Activation of NF-kappaB/Rel by CD40 engagement induces the mouse germ line immunoglobulin Cgamma1 promoter |
| Q72650413 | Allergy-associated I epsilon and Ec epsilon receptor II (CD23b) genes activated via binding of an interleukin-4-induced transcription factor to a novel responsive element |
| Q36230973 | An antisense oligonucleotide complementary to a sequence in I gamma 2b increases gamma 2b germline transcripts, stimulates B cell DNA synthesis, and inhibits immunoglobulin secretion |
| Q77398147 | Analysis of cytokine signaling in patients with extrinsic asthma and hyperimmunoglobulin E |
| Q36363460 | Anti-immunoglobulin E treatment decreases worm burden and egg production in Schistosoma mansoni-infected normal and interferon gamma knockout mice |
| Q36231123 | Antibody class switch recombination: roles for switch sequences and mismatch repair proteins |
| Q39716463 | Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extrachromosomal substrates |
| Q51137728 | B cell differentiation induced by helper T cell membranes: evidence for sequential isotype switching and a requirement for lymphokines during proliferation. |
| Q51119695 | B1 and B2 cells differ in their potential to switch immunoglobulin isotype. |
| Q52050435 | Blimp-1 overcomes the block in IgM secretion in lipopolysaccharide/anti-mu F(ab')2-co-stimulated B lymphocytes. |
| Q33918803 | CD300f:IL-5 cross-talk inhibits adipose tissue eosinophil homing and subsequent IL-4 production |
| Q71930227 | CD40 signaling induces interleukin-4-independent IgE switching in vivo |
| Q38293841 | Cell cycle regulation of immunoglobulin class switch recombination and germ-line transcription: potential role of Ets family members |
| Q40912655 | Cellular signalling mechanisms in B lymphocytes |
| Q36364256 | Characterization of an interleukin 4 (IL-4) responsive region in the immunoglobulin heavy chain germline epsilon promoter: regulation by NF-IL-4, a C/EBP family member and NF-kappa B/p50. |
| Q83874909 | Class switch recombination in selective IgA-deficient subjects |
| Q36404262 | Class switching in B cells lacking 3' immunoglobulin heavy chain enhancers. |
| Q35174996 | Clonal variants of hybridoma cells that switch isotype at a high frequency |
| Q36828990 | Coexpression of mu and gamma 1 heavy chains can occur by a discontinuous transcription mechanism from the same unrearranged chromosome |
| Q36316915 | Combinatorial mechanisms regulating AID-dependent DNA deamination: interacting proteins and post-translational modifications |
| Q35785980 | Demonstration of a divergent transcript from the bidirectional heavy chain immunoglobulin promoter VH441 in B-cells |
| Q73043244 | Direct and sequential switching from mu to epsilon in patients with Schistosoma mansoni infection and atopic dermatitis |
| Q36539209 | Diversity of cytokine synthesis and function of mouse CD4+ T cells |
| Q34596833 | Downstream boundary of chromosomal R-loops at murine switch regions: implications for the mechanism of class switch recombination |
| Q41576708 | Evidence for a human IgG1 class switch program |
| Q60420297 | Evidence for recombinatorial hot spots at the T cell receptor Jα locus |
| Q36845675 | Evolution of the immunoglobulin heavy chain class switch recombination mechanism |
| Q28508214 | Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis |
| Q54751752 | Expression of IgE heavy chain transcripts in the sinus mucosa of atopic and nonatopic patients with chronic sinusitis. |
| Q33947867 | Expression of activation-induced cytidine deaminase is regulated by cell division, providing a mechanistic basis for division-linked class switch recombination |
| Q41391954 | Failure of IgG production due to a defect in the opening of the chromatin structure of I gamma 1 region in a patient with IgG and IgA deficiency |
| Q68914335 | Frequencies of interleukin-5 mRNA-producing cells in healthy individuals and in immunoglobulin-deficient patients, measured by in situ hybridization |
| Q62606024 | Genetic recombination of nucleosomal templates is mediated by transcription |
| Q57213511 | Genetic regulation of antibody responsiveness to immunization in substrains of BALB/c mice |
| Q71976528 | Germ-line human epsilon heavy chain gene RNA transcripts utilize the full range of alternative 3' splicing seen in productive epsilon mRNA |
| Q41556630 | Human CD3-CD16+ natural killer cells express the hGATA-3 T cell transcription factor and an unrearranged 2.3-kb TcR delta transcript. |
| Q41720191 | Human IgE mRNA expression by peripheral blood lymphocytes stimulated with interleukin 4 and pokeweed mitogen |
| Q34289925 | Human antibodies from transgenic mice |
| Q38332521 | Identification of a conserved lipopolysaccharide-plus-interleukin-4-responsive element located at the promoter of germ line epsilon transcripts |
| Q36763010 | Identification of a germ line transcript from the unrearranged kappa gene in human B cells |
| Q40900090 | Identification of a stimulus-dependent DNase I hypersensitive site between the Ialpha and Calpha exons during immunoglobulin heavy chain class switch recombination |
| Q38299856 | Identification of the IgG1 Induction Factor (Interleukin 4). |
| Q37350490 | IgA class switch in I alpha exon-deficient mice. Role of germline transcription in class switch recombination |
| Q34292243 | IgE secretion by Epstein-Barr virus-infected purified human B lymphocytes is stimulated by interleukin 4 and suppressed by interferon gamma |
| Q28285566 | Immunoglobulin class switching |
| Q72600523 | Immunology of leishmaniasis |
| Q36363224 | Independent regulation of DNA recombination and immunoglobulin (Ig) secretion during isotype switching to IgG1 and IgE |
| Q68428815 | Induction of B cell activities by interleukin 4 is inhibited by a receptor-specific monoclonal antibody in vitro |
| Q45110397 | Induction of RNA-stabilized DMA conformers by transcription of an immunoglobulin switch region |
| Q68090772 | Induction of germ-line immunoglobulin heavy chain transcripts by mitogens and interleukins prior to switch recombination |
| Q39416642 | Influence of transcription and replication on the in situ resolution of immunoglobulin heavy-chain constant region genes: an interphase cytogenetics analysis |
| Q36707969 | Initiation and processing of two kappa immunoglobulin germ line transcripts in mouse B cells |
| Q36367533 | Interleukin (IL)-4-independent immunoglobulin class switch to immunoglobulin (Ig)E in the mouse |
| Q36352086 | Interleukin 4 induces changes in the chromatin structure of the gamma 1 switch region in resting B cells before switch recombination |
| Q30435016 | Interleukin 5 (IL-5) provides a signal that is required in addition to IL-4 for isotype switching to immunoglobulin (Ig) G1 and IgE |
| Q36362532 | Interleukin 5 induces S mu-S gamma 1 DNA rearrangement in B cells activated with dextran-anti-IgD antibodies and interleukin 4: a three component model for Ig class switching |
| Q35320758 | Isotype switching in CD5 B cells |
| Q30450001 | Isotype switching in anti-immunoglobulin-activated B lymphoblasts: differential requirements for interleukin 4 and other lymphokines to elicit membrane vs. secreted IgG1. |
| Q37748073 | Long noncoding RNAs: implications for antigen receptor diversification |
| Q40850235 | Mechanism and regulation of immunoglobulin isotype switching. |
| Q41336926 | Methylation patterns of I epsilon region in B cells stimulated with interleukin 4 and Epstein-Barr virus in patients with a high level of serum IgE. |
| Q35992414 | Mice lacking Sμ tandem repeats maintain RNA polymerase patterns but exhibit histone modification pattern shifts linked to class switch site locations |
| Q33594738 | Molecular characterization of germ-line immunoglobulin A transcripts produced during transforming growth factor type beta-induced isotype switching |
| Q37532213 | Molecular effects of cholera toxin on isotype differentiation |
| Q37330945 | Molecular mechanism for generation of antibody memory |
| Q30964186 | Murine memory B cells are multi-isotype expressors |
| Q44014620 | Myb proteins repress human Ig epsilon germline transcription by inhibiting STAT6-dependent promoter activation |
| Q34479651 | Negative regulation of activation-induced cytidine deaminase in B cells |
| Q41486524 | New insights into the pathogenesis and management of steroid-resistant asthma |
| Q34009625 | Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune response |
| Q34033751 | One cytokine, two isotypes: a trojan horse, pandora's box, and an evolving paradigm |
| Q36361426 | Ordered rearrangement of variable region genes of the T cell receptor gamma locus correlates with transcription of the unrearranged genes. |
| Q41478150 | Phenotypic, functional and molecular analysis of CD3- LGL expansions indicates a relationship to two different CD3- normal counterparts |
| Q40347275 | Presence of immunoglobulin (Ig) M and IgG double isotype-bearing cells and defect of switch recombination in hyper IgM immunodeficiency |
| Q52057514 | Prolonged in vivo IL-4 treatment inhibits antigen-specific IgG1 and IgE formation. |
| Q41720187 | Protective methylation of immunoglobulin and T cell receptor (TcR) gene loci prior to induction of class switch and TcR recombination |
| Q55002369 | RNA Helicase DDX1 Converts RNA G-Quadruplex Structures into R-Loops to Promote IgH Class Switch Recombination. |
| Q40397112 | RNA:DNA complex formation upon transcription of immunoglobulin switch regions: implications for the mechanism and regulation of class switch recombination |
| Q41603870 | Reciprocal regulatory effects of IL-4 on cell growth and immunoglobulin production in Ig-secreting human B-cell lines |
| Q36741294 | Recombinant CD40 ligand stimulation of murine B cell growth and differentiation: cooperative effects of cytokines |
| Q52578670 | Recurrent disruption of the Imu splice donor site in t(14;18) positive lymphomas: a potential molecular basis for aberrant downstream class switch recombination. |
| Q37730047 | Regulating infidelity: RNA-mediated recruitment of AID to DNA during class switch recombination |
| Q38681300 | Regulation of IgA synthesis and immune response by T cells and interleukins |
| Q40841083 | Regulation of IgE synthesis: from the membrane to the genes |
| Q38534704 | Regulation of IgG1 and IgE synthesis by interleukin 4 in mouse B cells |
| Q34115234 | Regulation of immunoglobulin class-switch recombination: choreography of noncoding transcription, targeted DNA deamination, and long-range DNA repair |
| Q41702567 | Regulation of the antibody class switch to IgA. |
| Q41513964 | Regulation of transcription of immunoglobulin germ-line gamma 1 RNA: analysis of the promoter/enhancer |
| Q36259698 | Replacement of germ-line epsilon promoter by gene targeting alters control of immunoglobulin heavy chain class switching |
| Q69353113 | Reticulum cell sarcomas of SJL mice have rearranged immunoglobulin heavy and light chain genes |
| Q60302530 | Ribonuclease H1-targeted R-loops in surface antigen gene expression sites can direct trypanosome immune evasion |
| Q37628479 | S region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process |
| Q40791221 | STF-IL-4: a novel IL-4-induced signal transducing factor |
| Q42147072 | Secondary immunoglobulin responses of BALB/c mice previously stimulated with goat anti-mouse IgD. |
| Q24594717 | Sequences of human immunoglobulin switch regions: implications for recombination and transcription |
| Q32036597 | Somatic mutations in the Ig variable region genes and expression of novel Cmu-germline transcripts in a B-lymphoma cell line ("Farage") not producing Ig polypeptide chains |
| Q36755800 | Structure and expression of germ line immunoglobulin heavy-chain epsilon transcripts: interleukin-4 plus lipopolysaccharide-directed switching to C epsilon |
| Q41727465 | Structure and expression of germline epsilon transcripts in human B cells induced by interleukin 4 to switch to IgE production |
| Q44501302 | Structure and expression of mouse germline immunoglobulin γ3 heavy chain transcripts induced by the mitogen lipopolysaccharide |
| Q37701973 | Structure and expression of murine germ-line immunoglobulin epsilon heavy chain transcripts induced by interleukin 4. |
| Q36714537 | Structure of germ line immunoglobulin alpha heavy-chain RNA and its location on polysomes |
| Q33850935 | Synthesis of germ-line gamma 1 immunoglobulin heavy-chain transcripts in resting B cells: induction by interleukin 4 and inhibition by interferon gamma |
| Q28588979 | T-bet regulates IgG class switching and pathogenic autoantibody production |
| Q35534265 | T-cell receptor V elements regulate murine IgE production and airways responsiveness |
| Q38266449 | TRIF signaling is essential for TLR4-driven IgE class switching |
| Q40982327 | Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions |
| Q59098629 | The B-cell-specific transcription coactivator OCA-B/OBF-1/Bob-1 is essential for normal production of immunoglobulin isotypes |
| Q57191210 | The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination |
| Q33779223 | The ability of CD40L, but not lipopolysaccharide, to initiate immunoglobulin switching to immunoglobulin G1 is explained by differential induction of NF-kappaB/Rel proteins |
| Q41389958 | The immunoglobulin class switch: beyond "accessibility". |
| Q36675781 | The immunoglobulin heavy chain locus contains another B-cell-specific 3' enhancer close to the alpha constant region |
| Q41733130 | The immunoglobulin heavy-chain enhancer functions as the promoter for I mu sterile transcription |
| Q73224719 | The influence of transcriptional orientation on endogenous switch region function |
| Q35563059 | The lamina propria: a dynamic, complex mucosal compartment. An overview |
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| Q36150234 | The phosphoinositide 3-kinase signaling pathway in normal and malignant B cells: activation mechanisms, regulation and impact on cellular functions. |
| Q37532196 | The preference for switching to expression of the IgA isotype of antibody exhibited by B lymphocytes in Peyer's patches is likely due to intrinsic properties of their microenvironment |
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