Identification of a germ line transcript from the unrearranged kappa gene in human B cells

scientific article published on October 1989

Identification of a germ line transcript from the unrearranged kappa gene in human B cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.9.10.4560
P932PMC publication ID362544
P698PubMed publication ID2573834

P2093author name stringB G Van Ness
D J Martin
P2860cites workSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
Developmentally controlled and tissue-specific expression of unrearranged VH gene segmentsQ28259020
Evolution of human immunoglobulin kappa J region genesQ28264378
Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segmentsQ28273471
Somatic generation of antibody diversityQ29616439
Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genesQ33656152
Transcriptional and posttranscriptional control of immunoglobulin mRNA production during B lymphocyte developmentQ35046574
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.Q35203032
DNA between variable and joining gene segments of immunoglobulin kappa light chain is frequently retained in cells that rearrange the kappa locusQ36275944
Transcription of mouse kappa chain genes: implications for allelic exclusionQ36363057
The coupling between enhancer activity and hypomethylation of kappa immunoglobulin genes is developmentally regulatedQ36784013
Structure and expression of germ line immunoglobulin gamma 2b transcriptsQ36787710
Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region geneQ37337101
Inducible transcription of the unrearranged kappa constant region locus is a common feature of pre-B cells and does not require DNA or protein synthesisQ37527636
Regulation of genome rearrangement events during lymphocyte differentiationQ39587594
Regulation of the assembly and expression of variable-region genesQ39588958
15 Detection of specific RNAs or specific fragments of DNA by fractionation in gels and transfer to diazobenzyloxymethyl paperQ39590366
A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutationQ39673191
Development of the primary antibody repertoireQ39682083
Characterization of a unique cell line (LAZ 221) from human acute lymphocytic ("null" cell) leukemiaQ40139503
Establishment of a leukemic cell model for studying human pre-B to B cell differentiation.Q42815875
The role of the kappa enhancer and its binding factor NF-kappa B in the developmental regulation of kappa gene transcriptionQ43814141
Immunoglobulin gene rearrangements and expression in diffuse histiocytic lymphomas reveal cellular lineage, molecular defects, and sites of chromosomal translocationQ44353834
Regulated progression of a cultured pre-B-cell line to the B-cell stage.Q53542424
Novel immunoglobulin heavy chains are produced from DJH gene segment rearrangements in lymphoid cellsQ59098599
Studies on the role of actin's N tau-methylhistidine using oligodeoxynucleotide-directed site-specific mutagenesisQ68172221
Mechanisms that regulate immunoglobulin gene expressionQ69875343
Identification and purification of a human lymphoid-specific octamer-binding protein (OTF-2) that activates transcription of an immunoglobulin promoter in vitroQ70366236
Transcription of the unrearranged mouse Cκ locus: Sequence of the initiation region and comparison of activity with a rearranged Vκ-Cκ geneQ72417657
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)4560-4562
P577publication date1989-10-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleIdentification of a germ line transcript from the unrearranged kappa gene in human B cells
P478volume9

Reverse relations

cites work (P2860)
Q41591551Immunoglobulin kappa light chain germ-line transcripts in human precursor B lymphocytes
Q36230012Induced rearrangement of kappa genes in the BLIN-1 human pre-B cell line correlates with germline J-C kappa and V kappa transcription
Q36707969Initiation and processing of two kappa immunoglobulin germ line transcripts in mouse B cells
Q33320319Molecular heterogeneity of the 1.0-kb T beta transcript in natural killer and gamma/delta lymphocytes
Q39718297Octamer independent activation of transcription from the kappa immunoglobulin germline promoter
Q41654573Re-organization of the immunoglobulin kappa gene on both alleles is not an obligatory prerequisite for Ig lambda gene expression in human cells
Q47911157Regulation of immunoglobulin light chain isotype expression
Q34822524The proximal J kappa germline-transcript promoter facilitates receptor editing through control of ordered recombination
Q24624280mRNA transcripts initiating within the human immunoglobulin mu heavy chain enhancer region contain a non-translatable exon and are extremely heterogeneous at the 5' end

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