Infection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection

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Infection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1006387844
P356DOI10.1186/1471-230X-10-92
P932PMC publication ID2928758
P698PubMed publication ID20707918

P50authorGerard AragonèsQ42175522
Carlos Alonso VillaverdeQ42175527
Javier A MenendezQ56503568
Anna RullQ41530405
Jorge JovenQ41878569
Raúl Beltrán-DebónQ42175504
P2093author name stringJordi Camps
Cristina Oliveras-Ferraros
Fernando Rodríguez-Sanabria
Alejandro Vázquez Martín
P2860cites workA new model ELISA, based on two monoclonal antibodies, for quantification of fatty acid synthaseQ44134496
Low density lipoprotein apolipoprotein B metabolism in treatment-naive HIV patients and patients on antiretroviral therapy.Q46694442
Evaluation of a homogeneous assay for high-density lipoprotein cholesterol: limitations in patients with cardiovascular, renal, and hepatic disorders.Q47980325
Limitations of the Friedewald formula for estimating low-density lipoprotein cholesterol in alcoholics with liver disease.Q52380530
Serum concentrations of extracellular fatty acid synthase in patients with steatohepatitisQ59450201
Atherosclerosis in Patients Infected With HIV Is Influenced by a Mutant Monocyte Chemoattractant Protein-1 AlleleQ59540708
The role of circulating monocyte chemoattractant protein-1 as a marker of hepatic inflammation in patients with chronic liver diseaseQ61945529
Fatty acid synthase (FAS) expression in human breast cancer cell culture supernatants and in breast cancer patientsQ73807088
AMP-Activated Protein Kinase in Metabolic Control and Insulin SignalingQ22241925
Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteinsQ27478188
Fatty acid synthase is up-regulated during hepatitis C virus infection and regulates hepatitis C virus entry and productionQ27487550
Fatty acid synthase and the lipogenic phenotype in cancer pathogenesisQ29615683
Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents?Q31085526
Two-site ELISA for the quantitative determination of fatty acid synthaseQ31877198
HIV replication enhances production of free fatty acids, low density lipoproteins and many key proteins involved in lipid metabolism: a proteomics studyQ33361587
Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolismQ33830715
Estrogen receptor-alpha mediates gender differences in atherosclerosis induced by HIV protease inhibitorsQ34335180
Integration of human immunodeficiency virus type 1 in untreated infection occurs preferentially within genesQ35023783
Mechanisms and strategies for insulin resistance in acquired immune deficiency syndromeQ35207207
AMPK-mediated inhibition of mTOR kinase is circumvented during immediate-early times of human cytomegalovirus infectionQ35785196
Quantitative analysis of human immunodeficiency virus type 1-infected CD4+ cell proteome: dysregulated cell cycle progression and nuclear transport coincide with robust virus productionQ35914539
Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells.Q35971273
Impact of HIV and highly active antiretroviral therapy on leukocyte adhesion molecules, arterial inflammation, dyslipidemia, and atherosclerosisQ36317218
Oncogenic properties of the endogenous fatty acid metabolism: molecular pathology of fatty acid synthase in cancer cells.Q36508454
Targeting fatty acid synthase in breast and endometrial cancer: An alternative to selective estrogen receptor modulators?Q36523601
Insulin resistance and HIV infection: a reviewQ36741551
AMPK: a key regulator of energy balance in the single cell and the whole organism.Q37249357
AMPK: a metabolic gauge regulating whole-body energy homeostasisQ37314854
Metabolic disorders and chronic viral disease: the case of HIV and HCV.Q37338593
Acute hepatitis C in HIV-positive individuals.Q37353887
HIV-associated vascular diseases: structural and functional changes, clinical implications.Q37364877
Physiological and pathophysiological roles of adiponectin and adiponectin receptors in the integrated regulation of metabolic and cardiovascular diseasesQ37366361
Fatty acid synthase: association with insulin resistance, type 2 diabetes, and cancerQ37381193
Hepatitis C, human immunodeficiency virus and metabolic syndrome: interactionsQ37383401
Elevated levels of interleukin-8 in serum are associated with hepatitis C virus infection and resistance to interferon therapyQ39603332
AMPK-sensed cellular energy state regulates the release of extracellular Fatty Acid SynthaseQ39912447
The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival.Q40426889
Fatty acid synthase as a tumor marker: its extracellular expression in human breast cancerQ40500897
Inhibition of tumor-associated fatty acid synthase activity antagonizes estradiol- and tamoxifen-induced agonist transactivation of estrogen receptor (ER) in human endometrial adenocarcinoma cellsQ40565118
Activation of promoters for cellular lipogenic genes by hepatitis B virus large surface proteinQ40831789
P921main subjectfatty acidQ61476
P304page(s)92
P577publication date2010-08-13
P1433published inBMC GastroenterologyQ15759922
P1476titleInfection with HIV and HCV enhances the release of fatty acid synthase into circulation: evidence for a novel indicator of viral infection
P478volume10

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cites work (P2860)
Q47405719A systematic review of the associations between HIV/HCV coinfection and biomarkers of cardiovascular disease.
Q41927731Cellular fatty acid synthase is required for late stages of HIV-1 replication.
Q42263054Differential Regulation of Host Genes Including Hepatic Fatty Acid Synthase in HBV-Transgenic Mice
Q36158019Dysregulation of glucose metabolism in HIV patients: epidemiology, mechanisms, and management
Q50044384Fatty acid synthase (FASN) as a therapeutic target in breast cancer.
Q24318935Hepatitis C virus replication is modulated by the interaction of nonstructural protein NS5B and fatty acid synthase
Q36224063Lipids and RNA virus replication
Q45961719Metformin: a cheap and well-tolerated drug that provides benefits for viral infections.
Q37512558Perturbations of lipid metabolism indexed by lipidomic biomarkers
Q40183703Profiling of esterified fatty acids as biomarkers in the blood of dengue fever patients using a microliter-scale extraction followed by gas chromatography and mass spectrometry.
Q36317694Symptom Status Predicts Patient Outcomes in Persons with HIV and Comorbid Liver Disease