The hemorrhagic coli pilus (HCP) of Escherichia coli O157:H7 is an inducer of proinflammatory cytokine secretion in intestinal epithelial cells

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The hemorrhagic coli pilus (HCP) of Escherichia coli O157:H7 is an inducer of proinflammatory cytokine secretion in intestinal epithelial cells is …
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scholarly articleQ13442814

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P819ADS bibcode2010PLoSO...512127L
P356DOI10.1371/JOURNAL.PONE.0012127
P932PMC publication ID2920817
P698PubMed publication ID20711431
P5875ResearchGate publication ID45651335

P2093author name stringJaime Mas-Oliva
Carlos A Eslava
Juan Xicohtencatl-Cortes
Sara A Ochoa
Jorge A Girón
Ariadnna Cruz
Maria A Ledesma
Luz M Rocha-Ramírez
P2860cites workIdentification of proinflammatory flagellin proteins in supernatants of Vibrio cholerae O1 by proteomics analysis.Q51129402
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An Inducible Bundle-Forming Pilus of Enteropathogenic Escherichia coliQ64450661
Molecular mechanism of interleukin-8 gene expressionQ71657166
Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cellsQ73948765
Activation of IL-8 gene expression by Helicobacter pylori is regulated by transcription factor nuclear factor-kappa B in gastric epithelial cellsQ74303703
TNF-alpha-independent IL-8 expression: alterations in bacterial challenge dose cause differential human monocytic cytokine responseQ94482871
Host protein binding and adhesive properties of H6 and H7 flagella of attaching and effacing Escherichia coliQ36314226
Infection by verocytotoxin-producing Escherichia coliQ36634680
D-myo-Inositol 1,4,5,6-tetrakisphosphate produced in human intestinal epithelial cells in response to Salmonella invasion inhibits phosphoinositide 3-kinase signaling pathwaysQ36819888
Salmonella typhimurium induces epithelial IL-8 expression via Ca(2+)-mediated activation of the NF-kappaB pathwayQ37303197
Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio choleraeQ39494481
Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis.Q39510203
Uropathogenic Escherichia coli potentiates type 1 pilus-induced apoptosis by suppressing NF-kappaB.Q39529408
Enterohemorrhagic Escherichia coli infection induces interleukin-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in T84 cellsQ39654974
Uropathogenic Escherichia coli dominantly suppress the innate immune response of bladder epithelial cells by a lipopolysaccharide- and Toll-like receptor 4-independent pathwayQ40016803
Shiga toxin produced by enterohemorrhagic Escherichia coli inhibits PI3K/NF-kappaB signaling pathway in globotriaosylceramide-3-negative human intestinal epithelial cellsQ40124024
Role of Shiga toxin versus H7 flagellin in enterohaemorrhagic Escherichia coli signalling of human colon epithelium in vivo.Q40293264
Pseudomonas aeruginosa flagellin and alginate elicit very distinct gene expression patterns in airway epithelial cells: implications for cystic fibrosis diseaseQ40501945
Induction of macrophage nitric oxide production by Gram-negative flagellin involves signaling via heteromeric Toll-like receptor 5/Toll-like receptor 4 complexesQ40641430
Detection of the K99 antigen by means of agglutination and immunoelectrophoresis in Escherichia coli isolates from calves and its correlation with entertoxigenicityQ40905748
Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli.Q41081300
Helicobacter pylori infection activates NF-kappa B in gastric epithelial cellsQ41088207
NF-kappa B is a central regulator of the intestinal epithelial cell innate immune response induced by infection with enteroinvasive bacteriaQ41482284
Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuliQ41627054
Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.Q42645426
Analysis of fimbrial gene clusters and their expression in enterohaemorrhagic Escherichia coli O157:H7.Q43220530
Hemolytic uremic syndrome: epidemiology, pathophysiology, and therapyQ43695930
PKC zeta participates in activation of inflammatory response induced by enteropathogenic E. coliQ44538196
The bundle-forming pili of enteropathogenic Escherichia coli: transcriptional regulation by environmental signalsQ46411600
Role of EHEC O157:H7 virulence factors in the activation of intestinal epithelial cell NF-kappaB and MAP kinase pathways and the upregulated expression of interleukin 8.Q46809881
EPEC-activated ERK1/2 participate in inflammatory response but not tight junction barrier disruptionQ50113307
Flagellin, a novel mediator of Salmonella-induced epithelial activation and systemic inflammation: I kappa B alpha degradation, induction of nitric oxide synthase, induction of proinflammatory mediators, and cardiovascular dysfunctionQ50117610
Genome sequence of enterohaemorrhagic Escherichia coli O157:H7Q22122385
Diarrheagenic Escherichia coliQ24533466
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR productsQ27860842
Signal transduction by the JNK group of MAP kinasesQ28142592
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expressionQ28211358
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory responseQ28345391
Role of flagella in pathogenesis of Pseudomonas aeruginosa pulmonary infectionQ28493023
Type IV pili and twitching motilityQ29615262
Enteroaggregative Escherichia coli expresses a novel flagellin that causes IL-8 release from intestinal epithelial cells.Q30305779
Shiga toxins stimulate secretion of interleukin-8 from intestinal epithelial cellsQ33330360
Intestinal adherence associated with type IV pili of enterohemorrhagic Escherichia coli O157:H7Q33377069
The type 4 pili of enterohemorrhagic Escherichia coli O157:H7 are multipurpose structures with pathogenic attributesQ33381776
Shiga toxin-associated hemolytic-uremic syndrome: combined cytotoxic effects of Shiga toxin, interleukin-1 beta, and tumor necrosis factor alpha on human vascular endothelial cells in vitroQ33384145
Illnesses associated with Escherichia coli O157:H7 infections. A broad clinical spectrumQ33445897
High-affinity interaction between gram-negative flagellin and a cell surface polypeptide results in human monocyte activationQ33591155
Epithelial cells secrete the chemokine interleukin-8 in response to bacterial entry.Q33613340
A Vibrio vulnificus type IV pilin contributes to biofilm formation, adherence to epithelial cells, and virulenceQ33716002
Role of tumor necrosis factor alpha in gnotobiotic mice infected with an Escherichia coli O157:H7 strainQ33748229
Salmonella typhi flagella are potent inducers of proinflammatory cytokine secretion by human monocytes.Q33877245
5'-adenosine monophosphate is the neutrophil-derived paracrine factor that elicits chloride secretion from T84 intestinal epithelial cell monolayersQ33900552
Neisseria gonorrhoeae PilV, a type IV pilus-associated protein essential to human epithelial cell adherenceQ33953123
Hemorrhagic Colitis Associated with a RareEscherichia coliSerotypeQ34256166
Use of phoA gene fusions to identify a pilus colonization factor coordinately regulated with cholera toxinQ34618561
Flagellin of enteropathogenic Escherichia coli stimulates interleukin-8 production in T84 cellsQ34853145
Temperature- and medium-dependent secretion of proteins by Shiga toxin-producing Escherichia coli.Q35527573
Type IV pilus structure and bacterial pathogenicityQ35752406
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)e12127
P577publication date2010-08-12
P1433published inPLOS OneQ564954
P1476titleThe hemorrhagic coli pilus (HCP) of Escherichia coli O157:H7 is an inducer of proinflammatory cytokine secretion in intestinal epithelial cells
P478volume5

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cites work (P2860)
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Q56561706The Fimbrial Gene in Enterohemorrhagic O157:H7 Contributes to Bacterial Pathogenicity
Q39256913The long polar fimbriae of STEC O157:H7 induce expression of pro-inflammatory markers by intestinal epithelial cells.

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