Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer

scientific article

Poly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1097/PPO.0B013E3181CF01EB
P932PMC publication ID4035043
P698PubMed publication ID20164690

P50authorMark RobsonQ51026477
P2093author name stringElizabeth A Comen
P2860cites workDNA Damage, Aging, and CancerQ22121931
High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugsQ24644255
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Cisplatin: mode of cytotoxic action and molecular basis of resistanceQ29615385
Poly(ADP-ribose): novel functions for an old moleculeQ29617735
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Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumorsQ33896961
Methylation of the BRCA1 promoter is associated with decreased BRCA1 mRNA levels in clinical breast cancer specimensQ33915724
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Poly(ADP-ribose) polymerase-1 inhibitor treatment regresses autochthonous Brca2/p53-mutant mammary tumors in vivo and delays tumor relapse in combination with carboplatin.Q34017159
Localization of human BRCA1 and its loss in high-grade, non-inherited breast carcinomasQ34492521
Utility of DNA repair protein foci for the detection of putative BRCA1 pathway defects in breast cancer biopsiesQ34550979
Toward specific functions of poly(ADP-ribose) polymerase-2.Q34763353
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouseQ35018839
Synthetic lethal targeting of PTEN mutant cells with PARP inhibitorsQ36042091
Poly(ADP-ribose) polymerase and the therapeutic effects of its inhibitorsQ36111918
Role of poly(ADP-ribose) polymerase 1 (PARP-1) in cardiovascular diseases: the therapeutic potential of PARP inhibitorsQ36426742
Requirement of poly(ADP-ribose) polymerase in recovery from DNA damage in mice and in cellsQ36654891
Mammalian single-strand break repair: mechanisms and links with chromatinQ36659772
A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modificationQ36751371
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Poly ADP-ribose polymerase-1: an international molecule of mysteryQ37158860
A synthetic lethal therapeutic approach: poly(ADP) ribose polymerase inhibitors for the treatment of cancers deficient in DNA double-strand break repairQ37203855
Triple-negative breast cancer: risk factors to potential targetsQ37352430
Synthetic lethality: a framework for the development of wiser cancer therapeuticsQ37442913
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Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.Q39971672
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Expression of BRCA1 protein in breast cancer and its prognostic significanceQ42526565
Genetics of natural populations; recombination and variability in populations of Drosophila pseudoobscuraQ42969471
Targeting the molecular defect in BRCA-deficient tumors for cancer therapy.Q45914279
A high-throughput RNA interference screen for DNA repair determinants of PARP inhibitor sensitivityQ63383824
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatinQ64388522
Methylation of the BRCA1 promoter region in sporadic breast and ovarian cancer: correlation with disease characteristicsQ77340263
P433issue1
P304page(s)48-52
P577publication date2010-01-01
P1433published inThe Cancer JournalQ2589130
P1476titlePoly(ADP-ribose) polymerase inhibitors in triple-negative breast cancer
P478volume16

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