Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories

scientific article

Large-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1089/HUM.2009.096
P932PMC publication ID2829450
P698PubMed publication ID19719388
P5875ResearchGate publication ID26779128

P2093author name stringTerry K Bertin
Brendan Lee
Susana Mouriño
Masataka Suzuki
Racel Cela
Christian Clarke
P2860cites workActivation of innate immunity in nonhuman primates following intraportal administration of adenoviral vectors.Q33337331
A gene-deleted adenoviral vector results in phenotypic correction of canine hemophilia B without liver toxicity or thrombocytopeniaQ33348516
Helper-dependent adenoviral vectors mediate therapeutic factor VIII expression for several months with minimal accompanying toxicity in a canine model of severe hemophilia AQ33356962
A helper-dependent adenovirus vector system: removal of helper virus by Cre-mediated excision of the viral packaging signalQ35915922
Helper-dependent adenoviral vectors for gene therapyQ36036219
Administration of helper-dependent adenoviral vectors and sequential delivery of different vector serotype for long-term liver-directed gene transfer in baboonsQ36557727
Methods for the production of helper-dependent adenoviral vectorsQ39954011
Physical and infectious titers of helper-dependent adenoviral vectors: a method of direct comparison to the adenovirus reference materialQ40510393
Improved system for helper-dependent adenoviral vector productionQ40619668
Optimization of the generation and propagation of gutless adenoviral vectorsQ40663790
Construction of first-generation adenoviral vectors.Q40734635
Preparation of helper-dependent adenoviral vectorsQ40734638
Development of a FLP/frt system for generating helper-dependent adenoviral vectorsQ40805792
A Cre-expressing cell line and an E1/E2a double-deleted virus for preparation of helper-dependent adenovirus vectorQ40810172
Acute toxicity after high-dose systemic injection of helper-dependent adenoviral vectors into nonhuman primates.Q44765402
Correction of murine hemophilia A and immunological differences of factor VIII variants delivered by helper-dependent adenoviral vectorsQ45870948
Acute cytokine response to systemic adenoviral vectors in mice is mediated by dendritic cells and macrophagesQ45877053
Gutted adenoviral vector growth using E1/E2b/E3-deleted helper virusesQ64378497
P433issue1
P921main subjectAdenoviridaeQ193447
P304page(s)120-126
P577publication date2010-01-01
P1433published inHuman Gene TherapyQ15757580
P1476titleLarge-scale production of high-quality helper-dependent adenoviral vectors using adherent cells in cell factories
P478volume21

Reverse relations

cites work (P2860)
Q33877450A novel bicistronic high-capacity gutless adenovirus vector that drives constitutive expression of herpes simplex virus type 1 thymidine kinase and tet-inducible expression of Flt3L for glioma therapeutics
Q41925180Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer
Q38714964Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors
Q41429339Canine helper-dependent vectors production: implications of Cre activity and co-infection on adenovirus propagation.
Q42424335Capsid-modified adenoviral vectors for improved muscle-directed gene therapy
Q36664224Combinatorial treatment with oncolytic adenovirus and helper-dependent adenovirus augments adenoviral cancer gene therapy
Q36740271Differential type I interferon-dependent transgene silencing of helper-dependent adenoviral vs. adeno-associated viral vectors in vivo
Q36444154Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell Proteinopathy.
Q51847569Feasibility of Applying Helper-Dependent Adenoviral Vectors for Cancer Immunotherapy.
Q38302375Helper-dependent adenoviral vectors for liver-directed gene therapy of primary hyperoxaluria type 1.
Q34993431Helper-dependent adenovirus is superior to first-generation adenovirus for expressing transgenes in atherosclerosis-prone arteries
Q38945731Impact of adenovirus life cycle progression on the generation of canine helper-dependent vectors.
Q35226121NOD2 signaling contributes to the innate immune response against helper-dependent adenovirus vectors independently of MyD88 in vivo.
Q90974934No more helper adenovirus: production of gutless adenovirus (GLAd) free of adenovirus and replication-competent adenovirus (RCA) contaminants
Q90127107Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors
Q38719412Osteocyte-specific WNT1 regulates osteoblast function during bone homeostasis
Q34619757Proteoglycan 4 expression protects against the development of osteoarthritis
Q36678182Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1 null mice
Q36740254SR-A and SREC-I are Kupffer and endothelial cell receptors for helper-dependent adenoviral vectors
Q35224065SR-A and SREC-I binding peptides increase HDAd-mediated liver transduction.
Q45367025Self-inactivating helper virus for the production of high-capacity adenoviral vectors
Q39534390Single dose adenovirus vectored vaccine induces a potent and long-lasting immune response against rabbit hemorrhagic disease virus after parenteral or mucosal administration.
Q37225109Treatment of osteoarthritis using a helper-dependent adenoviral vector retargeted to chondrocytes