Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells

scientific article

Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.18632/ONCOTARGET.15843
P932PMC publication ID5438618
P698PubMed publication ID28427190

P50authorJingfeng TangQ83144785
Cefan ZhouQ89674143
P2093author name stringJing Yang
Yi Zhang
Xing-Zhen Chen
Huang Huang
Hui Xiong
Hongxia Cheng
Wenying Qin
Yefu Wang
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Spleen Tyrosine Kinase Confers Paclitaxel Resistance in Ovarian Cancer.Q53832317
Microtubule-interfering Agents Activate c-Jun N-terminal Kinase/Stress-activated Protein Kinase through Both Ras and Apoptosis Signal-regulating Kinase PathwaysQ57267084
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Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancerQ28306764
Abraxane, the Nanoparticle Formulation of Paclitaxel Can Induce Drug Resistance by Up-Regulation of P-gpQ28546603
A cytoplasmic inhibitor of the JNK signal transduction pathwayQ28586970
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosisQ29547567
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Mesenchymal stromal cells primed with paclitaxel provide a new approach for cancer therapyQ34113542
Pygo2 Associates with MLL2 Histone Methyltransferase and GCN5 Histone Acetyltransferase Complexes To Augment Wnt Target Gene Expression and Breast Cancer Stem-Like Cell ExpansionQ34416310
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Pygo2 functions as a prognostic factor for glioma due to its up-regulation of H3K4me3 and promotion of MLL1/MLL2 complex recruitment.Q36606033
Pygopus activates Wingless target gene transcription through the mediator complex subunits Med12 and Med13.Q36638798
Pygopus and the Wnt signaling pathway: a diverse set of connectionsQ37135610
Prognostic significance of PLIN1 expression in human breast cancer.Q37688087
Nanomedicinal strategies to treat multidrug-resistant tumors: current progressQ37763152
Recent progress with microtubule stabilizers: new compounds, binding modes and cellular activitiesQ38183686
Transcription factor c-Jun activation represses mdr-1 gene expression.Q38351649
Reversion of multidrug resistance by a pH-responsive cyclodextrin-derived nanomedicine in drug resistant cancer cellsQ38848601
Pygo2 siRNA Inhibit the Growth and Increase Apoptosis of U251 Cell by Suppressing Histone H3K4 TrimethylationQ38887767
Human CD14+ cells loaded with Paclitaxel inhibit in vitro cell proliferation of glioblastoma.Q38933927
Human skin-derived fibroblasts acquire in vitro anti-tumor potential after priming with Paclitaxel.Q39288934
The therapeutic efficacy of conjugated linoleic acid - paclitaxel on glioma in the rat.Q39709166
PHF8 targets histone methylation and RNA polymerase II to activate transcription.Q39710578
Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinaseQ40333053
Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugsQ40386853
Arginine482 to threonine mutation in the breast cancer resistance protein ABCG2 inhibits rhodamine 123 transport while increasing bindingQ40556790
Novel role for JNK as a stress-activated Bcl2 kinaseQ40809860
Suppression of anti-microtubule agent-induced apoptosis by nitric oxide: possible mechanism of a new drug resistanceQ41050392
Bcl-2 phosphorylation required for anti-apoptosis functionQ41111068
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.Q42110512
The role of Pygopus 2 in rat glioma cell growthQ44669927
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectmultiple drug resistanceQ643839
P304page(s)27915-27928
P577publication date2017-03-02
P1433published inOncotargetQ1573155
P1476titlePygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells
P478volume8

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cites work (P2860)
Q4974674620(S)-Protopanaxadiol induces apoptosis in human hepatoblastoma HepG2 cells by downregulating the protein kinase B signaling pathway
Q98163537LncRNA PVT1 promotes gemcitabine resistance of pancreatic cancer via activating Wnt/β-catenin and autophagy pathway through modulating the miR-619-5p/Pygo2 and miR-619-5p/ATG14 axes
Q60921650N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling

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