| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.2174/092986706777585077 |
| P698 | PubMed publication ID | 16842198 |
| P50 | author | Ricardo Pérez-Tomás | Q40086267 |
| P2093 | author name string | Ricardo Pérez-Tomás | |
| P433 | issue | 16 | |
| P921 | main subject | multiple drug resistance | Q643839 |
| P304 | page(s) | 1859-1876 | |
| P577 | publication date | 2006-01-01 | |
| P1433 | published in | Current Medicinal Chemistry | Q3007710 |
| P1476 | title | Multidrug resistance: retrospect and prospects in anti-cancer drug treatment | |
| P478 | volume | 13 |
| Q28541630 | A new 2α,5α,10β,14β-tetraacetoxy-4(20),11-taxadiene (SIA) derivative overcomes paclitaxel resistance by inhibiting MAPK signaling and increasing paclitaxel accumulation in breast cancer cells |
| Q49963933 | A novel fiber chimeric conditionally replicative adenovirus-Ad5/F35 for tumor therapy |
| Q37697608 | A phase 2 study of SP1049C, doxorubicin in P-glycoprotein-targeting pluronics, in patients with advanced adenocarcinoma of the esophagus and gastroesophageal junction |
| Q39590850 | A simple and fast microfluidic approach of same-single-cell analysis (SASCA) for the study of multidrug resistance modulation in cancer cells |
| Q33879326 | ABC transporters in CSCs membranes as a novel target for treating tumor relapse |
| Q36646747 | ABC transporters, neural stem cells and neurogenesis--a different perspective |
| Q37706336 | ABCG2 confers promotion in gastric cancer through modulating downstream CRKL in vitro combining with biostatistics mining |
| Q44145948 | ATP-binding cassette transporter enhances tolerance to DDT in Tetrahymena |
| Q49417795 | Acridone suppresses the proliferation of human breast cancer cells in vitro via ATP-binding cassette subfamily G member 2. |
| Q40077983 | Ad-PUMA sensitizes drug-resistant choriocarcinoma cells to chemotherapeutic agents |
| Q37149646 | Ancestry-related differences in gene expression: findings may enhance understanding of health disparities between populations |
| Q36509179 | Antitumor Agents 291 Expanded B-Ring Modification Study of 6,8,8-Triethyl Desmosdumotin B Analogues as Multidrug-Resistance Selective Agents |
| Q34153747 | Antitumor Agents. 280. Multidrug Resistance-Selective Desmosdumotin B Analogues |
| Q24617999 | Apatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transporters |
| Q37574928 | Apoptosis and glutathione: beyond an antioxidant. |
| Q53841527 | Arylamino Esters As P-Glycoprotein Modulators: SAR Studies to Establish Requirements for Potency and Selectivity. |
| Q39596096 | Aurones as modulators of ABCG2 and ABCB1: synthesis and structure-activity relationships |
| Q44479490 | Automated reagent-dispensing system for microfluidic cell biology assays |
| Q34253081 | Axitinib targeted cancer stemlike cells to enhance efficacy of chemotherapeutic drugs via inhibiting the drug transport function of ABCG2. |
| Q28538126 | BCRP/ABCG2 inhibition sensitizes hepatocellular carcinoma cells to sorafenib |
| Q28743513 | Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers |
| Q55024462 | Bio-Inspired Protein-Based Nanoformulations for Cancer Theranostics. |
| Q36175486 | Biodegradable mixed MPEG-SS-2SA/TPGS micelles for triggered intracellular release of paclitaxel and reversing multidrug resistance |
| Q27026080 | Biophysics of cell membrane lipids in cancer drug resistance: Implications for drug transport and drug delivery with nanoparticles |
| Q37899223 | Bugs and drugs: oncolytic virotherapy in combination with chemotherapy |
| Q38757753 | Cabazitaxel overcomes cisplatin resistance in germ cell tumour cells |
| Q39274516 | Cathepsin D acts as an essential mediator to promote malignancy of benign prostatic epithelium. |
| Q38506204 | Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1. |
| Q40074014 | Chinese medicinal compound delisheng has satisfactory anti-tumor activity, and is associated with up-regulation of endostatin in human hepatocellular carcinoma cell line HepG2 in three-dimensional culture |
| Q42229140 | Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy |
| Q35671428 | Chrysin enhances doxorubicin-induced cytotoxicity in human lung epithelial cancer cell lines: the role of glutathione |
| Q35955198 | Combination drug delivery approaches in metastatic breast cancer |
| Q39317565 | Combinatorial therapeutic approaches with RNAi and anticancer drugs using nanodrug delivery systems |
| Q37867584 | Combining conditionally replicating adenovirus-mediated gene therapy with chemotherapy: a novel antitumor approach |
| Q37154905 | Coniferyl Ferulate, a Strong Inhibitor of Glutathione S-Transferase Isolated from Radix Angelicae sinensis, Reverses Multidrug Resistance and Downregulates P-Glycoprotein |
| Q47685388 | Convergent evolution of medicines |
| Q36166672 | Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoprotein |
| Q40024579 | Cytotoxic effects and in vitro reversal of multidrug resistance by therapeutic ultrasound in human hepatocarcinoma cell line (HepG2). |
| Q39743950 | DNA methylation profiles of organic anion transporting polypeptide 1B3 in cancer cell lines |
| Q37707577 | Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro |
| Q38853487 | Design, synthesis, in vitro cytotoxic activity evaluation, and apoptosis-induction study of new 9(10H)-acridinone-1,2,3-triazoles. |
| Q39234186 | Detection of glycomic alterations induced by overexpression of p-glycoprotein on the surfaces of L1210 cells using sialic acid binding lectins |
| Q39172417 | Development of drug loaded nanoparticles for tumor targeting. Part 2: Enhancement of tumor penetration through receptor mediated transcytosis in 3D tumor models. |
| Q39388913 | Development of multifunctional hyaluronan-coated nanoparticles for imaging and drug delivery to cancer cells |
| Q33814552 | Direct assessment of P-glycoprotein efflux to determine tumor response to chemotherapy. |
| Q34255576 | Disruption of microtubules sensitizes the DNA damage-induced apoptosis through inhibiting nuclear factor κB (NF-κB) DNA-binding activity |
| Q39868014 | Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells |
| Q50190222 | Down-regulation of miR-210-3p encourages chemotherapy resistance of renal cell carcinoma via modulating ABCC1. |
| Q38941315 | Downregulation of MDR1 gene by cepharanthine hydrochloride is related to the activation of c-Jun/JNK in K562/ADR cells |
| Q36377493 | Doxorubicin-Hyaluronan Conjugated Super-Paramagnetic Iron Oxide Nanoparticles (DOX-HA-SPION) Enhanced Cytoplasmic Uptake of Doxorubicin and Modulated Apoptosis, IL-6 Release and NF-kappaB Activity in Human MDA-MB-231 Breast Cancer Cells |
| Q37008882 | Drug resistance in cancer - searching for mechanisms, markers and therapeutic agents |
| Q83360720 | Effect of BIBF 1120 on reversal of ABCB1-mediated multidrug resistance |
| Q47130486 | Effects of Histone Deacetylase Inhibitor Panobinostat (LBH589) on Bone Marrow Mononuclear Cells of Relapsed or Refractory Multiple Myeloma Patients and Its Mechanisms |
| Q64954259 | Effects of P-glycoprotein and its inhibitors on apoptosis in K562 cells. |
| Q39718646 | Effects of single and multiple flavonoids on BCRP-mediated accumulation, cytotoxicity and transport of mitoxantrone in vitro |
| Q38084554 | Efflux pump-mediated resistance in chemotherapy |
| Q50543751 | Energy resolved tandem mass spectrometry experiments for resolution of isobaric compounds: a case of cis/trans isomerism. |
| Q64287532 | Epinecidin-1, a highly potent marine antimicrobial peptide with anticancer and immunomodulatory activities |
| Q33574625 | Establishment of a human hepatoma multidrug resistant cell line in vitro |
| Q37705351 | Evaluation of in vivo P-glycoprotein phenotyping probes: a need for validation |
| Q35860275 | Fentanyl Enhances Hepatotoxicity of Paclitaxel via Inhibition of CYP3A4 and ABCB1 Transport Activity in Mice |
| Q58764302 | Folate and Borneol Modified Bifunctional Nanoparticles for Enhanced Oral Absorption |
| Q37207728 | From antimicrobial to anticancer peptides. A review |
| Q39159293 | From taxuspine x to structurally simplified taxanes with remarkable p-glycoprotein inhibitory activity. |
| Q38095361 | Functional block copolymer assemblies responsive to tumor and intracellular microenvironments for site-specific drug delivery and enhanced imaging performance. |
| Q41517180 | Fungicide efflux and the MgMFS1 transporter contribute to the multidrug resistance phenotype in Zymoseptoria tritici field isolates. |
| Q28472187 | Fungicide-driven evolution and molecular basis of multidrug resistance in field populations of the grey mould fungus Botrytis cinerea |
| Q35130652 | Gemcitabine Cytotoxicity: Interaction of Efflux and Deamination |
| Q33729237 | Genome-wide identification and evolution of ATP-binding cassette transporters in the ciliate Tetrahymena thermophila: A case of functional divergence in a multigene family |
| Q28535383 | Grape seed procyanidin reversal of p-glycoprotein associated multi-drug resistance via down-regulation of NF-κB and MAPK/ERK mediated YB-1 activity in A2780/T cells |
| Q35592570 | Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells |
| Q34555337 | Hippo pathway mediates resistance to cytotoxic drugs |
| Q90228299 | Hydrogel-Mediated DOX⋅HCl/PTX Delivery System for Breast Cancer Therapy |
| Q33769196 | Identification of a new peptide for fibrosarcoma tumor targeting and imaging in vivo |
| Q39632452 | In Vitro and In Vivo Inhibition of MRP Gene Expression and Reversal of Multidrug Resistance by siRNA |
| Q35793768 | In vitro Characterization of the Rapid Cytotoxicity of Anticancer Peptide HPRP-A2 through Membrane Destruction and Intracellular Mechanism against Gastric Cancer Cell Lines. |
| Q37070476 | In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs |
| Q39643999 | In vitro chemosensitivity of head and neck cancer cell lines. |
| Q43788758 | Increased susceptibility of a triclabendazole (TCBZ)-resistant isolate of Fasciola hepatica to TCBZ following co-incubation in vitro with the P-glycoprotein inhibitor, R(+)-verapamil |
| Q45850124 | Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate |
| Q39187613 | Influence of the multidrug transporter P-glycoprotein on the intracellular pharmacokinetics of vandetanib. |
| Q42786611 | Inhibition of P-glycoprotein pumps by PEO-PPO amphiphiles: branched versus linear derivatives |
| Q38896058 | Inhibition of mdr1 by G-quadruplex oligonucleotides and reversal of paclitaxel resistance in human ovarian cancer cells |
| Q37663392 | Inhibition of the multidrug resistance P-glycoprotein: time for a change of strategy? |
| Q39079389 | Integrated hollow mesoporous silica nanoparticles for target drug/siRNA co-delivery |
| Q33980155 | Integrating Epigenomics into Pharmacogenomic Studies |
| Q35848338 | Isolation of a novel bio-peptide from walnut residual protein inducing apoptosis and autophagy on cancer cells |
| Q36615913 | Key structure of brij for overcoming multidrug resistance in cancer |
| Q34416223 | Lapatinib antagonizes multidrug resistance-associated protein 1-mediated multidrug resistance by inhibiting its transport function |
| Q37938364 | Membrane-active host defense peptides--challenges and perspectives for the development of novel anticancer drugs |
| Q37334609 | Metnase mediates chromosome decatenation in acute leukemia cells |
| Q37763502 | Metronomic chemotherapy: new rationale for new directions |
| Q64889318 | MiR-34a overexpression enhances the inhibitory effect of doxorubicin on HepG2 cells. |
| Q33795090 | Micellar electrokinetic chromatographic analysis for in vitro accumulation of anthracyclines enhanced by inhibitors of cell membrane transporter-proteins in cancer cells |
| Q42180601 | Modulation of P-glycoprotein expression by triptolide in adriamycin-resistant K562/A02 cells |
| Q34394789 | Modulation of mitochondrial permeability transition pore affects multidrug resistance in human hepatocellular carcinoma cells |
| Q39895966 | Multi-drug-resistance-reverting agents: 2-aryloxazole and 2-arylthiazole derivatives as potent BCRP or MRP1 inhibitors |
| Q35667274 | Multidrug resistance protein (MRP) 4 attenuates benzo[a]pyrene-mediated DNA-adduct formation in human bronchoalveolar H358 cells. |
| Q38800311 | NANOG regulates epithelial-mesenchymal transition and chemoresistance through activation of the STAT3 pathway in epithelial ovarian cancer |
| Q27500424 | Nanomaterials for reversion of multidrug resistance in cancer: a new hope for an old idea? |
| Q38813380 | Nanoparticle delivery of anticancer drugs overcomes multidrug resistance in breast cancer |
| Q36057369 | Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo. |
| Q38928436 | Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways |
| Q79394813 | Nuclear medicine in the treatment of neuroendocrine tumours--problems and perspectives |
| Q35600198 | Oncolytic activities of host defense peptides |
| Q37185612 | Oncolytic virus efficiency inhibited growth of tumour cells with multiple drug resistant phenotype in vivo and in vitro |
| Q39545301 | Oroxylin A reverses multi-drug resistance of human hepatoma BEL7402/5-FU cells via downregulation of P-glycoprotein expression by inhibiting NF-κB signaling pathway. |
| Q38249954 | Overcoming multidrug resistance with nanomedicines |
| Q89976455 | PLAG Exerts Anti-Metastatic Effects by Interfering with Neutrophil Elastase/PAR2/EGFR Signaling in A549 Lung Cancer Orthotopic Model |
| Q38791794 | Perenosins: a new class of anion transporter with anti-cancer activity |
| Q33729158 | Phase I study of valspodar (PSC-833) with mitoxantrone and etoposide in refractory and relapsed pediatric acute leukemia: a report from the Children's Oncology Group |
| Q37079989 | Phenylboronic acid selectively inhibits human prostate and breast cancer cell migration and decreases viability |
| Q34620809 | Pien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway |
| Q33991881 | Positron emission tomography molecular imaging for drug development |
| Q90529019 | Progress in the treatment of solid tumors with apatinib: a systematic review |
| Q33709499 | Pygopus2 inhibits the efficacy of paclitaxel-induced apoptosis and induces multidrug resistance in human glioma cells |
| Q59113724 | Radiosensitizing and Hyperthermic Properties of Hyaluronan Conjugated, Dextran-Coated Ferric Oxide Nanoparticles: Implications for Cancer Stem Cell Therapy |
| Q34663768 | Rapid cytotoxicity of antimicrobial peptide tempoprin-1CEa in breast cancer cells through membrane destruction and intracellular calcium mechanism |
| Q33730375 | Recent advances on the molecular mechanisms involved in the drug resistance of cancer cells and novel targeting therapies |
| Q55256284 | Reconstitution and functional studies of hamster P-glycoprotein in giant liposomes. |
| Q50067842 | Regulation of drug resistance and metastasis of gastric cancer cells via the microRNA647-ANK2 axis |
| Q53829100 | Reversal of P-glycoprotein-mediated multidrug resistance by the novel tetrandrine derivative W6. |
| Q37575644 | Role of membrane transporters in the safety profile of drugs |
| Q36241753 | Role of mitochondrial translocation of telomerase in hepatocellular carcinoma cells with multidrug resistance |
| Q38757793 | Selective GPR55 antagonism reduces chemoresistance in cancer cells |
| Q39084283 | Sigma-2 receptor agonists as possible antitumor agents in resistant tumors: hints for collateral sensitivity |
| Q42434544 | Silencing MRP1-4 genes by RNA interference enhances sensitivity of human hepatoma cells to chemotherapy |
| Q36662847 | Single-step doxorubicin-selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes. |
| Q24293500 | Small molecule inhibition of the KRAS-PDEδ interaction impairs oncogenic KRAS signalling |
| Q40160149 | Sonic Hedgehog promotes multiple drug resistance by regulation of drug transport |
| Q28553903 | Specific Anti-Leukemic Activity of the Peptide Warnericin RK and Analogues and Visualization of Their Effect on Cancer Cells by Chemical Raman Imaging |
| Q37802552 | Sphingolipids and expression regulation of genes in cancer. |
| Q48344291 | Structure-Activity Relationship Studies on 6,7-Dimethoxy-2-phenethyl-1,2,3,4-tetrahydroisoquinoline Derivatives as Multidrug Resistance Reversers. |
| Q39980204 | Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R). |
| Q35670917 | Suppression of MAPK Signaling and Reversal of mTOR-Dependent MDR1-Associated Multidrug Resistance by 21α-Methylmelianodiol in Lung Cancer Cells |
| Q36498973 | Sustained Epigenetic Drug Delivery Depletes Cholesterol-Sphingomyelin Rafts from Resistant Breast Cancer Cells, Influencing Biophysical Characteristics of Membrane Lipids |
| Q60197490 | Synthesis of an Original Oxygenated Taxuspine X Analogue: a Versatile “Non-Natural” Natural Product with Remarkable P-gp Modulating Activity |
| Q39411290 | Synthesis of anticancer heptapeptides containing a unique lipophilic β(2,2) -amino acid building block. |
| Q39400320 | Synthesis, PASS-Predication and in Vitro Antimicrobial Activity of Benzyl 4-O-benzoyl-α-l-rhamnopyranoside Derivatives. |
| Q34483601 | TALEN-mediated Nanog disruption results in less invasiveness, more chemosensitivity and reversal of EMT in Hela cells |
| Q39023976 | TLR4 induces tumor growth and inhibits paclitaxel activity in MyD88-positive human ovarian carcinoma in vitro |
| Q33584376 | TTFields alone and in combination with chemotherapeutic agents effectively reduce the viability of MDR cell sub-lines that over-express ABC transporters |
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