In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs

scientific article published on 17 August 2011

In vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs is …
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scholarly articleQ13442814

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P356DOI10.1016/J.BCP.2011.08.002
P932PMC publication ID3733550
P698PubMed publication ID21855533

P2093author name stringSuresh V Ambudkar
Chung-Pu Wu
Hong-May Sim
Mei-Lin Go
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Evidence for dual mode of action of a thiosemicarbazone, NSC73306: a potent substrate of the multidrug resistance linked ABCG2 transporter.Q36496944
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Sunitinib (Sutent, SU11248), a small-molecule receptor tyrosine kinase inhibitor, blocks function of the ATP-binding cassette (ABC) transporters P-glycoprotein (ABCB1) and ABCG2.Q37188016
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Aurones as modulators of ABCG2 and ABCB1: synthesis and structure-activity relationshipsQ39596096
Modulation of function of three ABC drug transporters, P-glycoprotein (ABCB1), mitoxantrone resistance protein (ABCG2) and multidrug resistance protein 1 (ABCC1) by tetrahydrocurcumin, a major metabolite of curcumin.Q40234208
The calcium channel blockers, 1,4-dihydropyridines, are substrates of the multidrug resistance-linked ABC drug transporter, ABCG2.Q40254927
Differential sensitivities of the human ATP-binding cassette transporters ABCG2 and P-glycoprotein to cyclosporin A.Q40480676
Biochemical mechanism of modulation of human P-glycoprotein (ABCB1) by curcumin I, II, and III purified from Turmeric powder.Q40505531
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.Q40904151
Issues in experimental design and endpoint analysis in the study of experimental cytotoxic agents in vivo in breast cancer and other models.Q41710325
Tumorigenicity and metastasis of human breast carcinoma cell lines in nude miceQ41745394
Relation between the turnover number for vinblastine transport and for vinblastine-stimulated ATP hydrolysis by human P-glycoproteinQ42797493
Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein).Q43499038
Potent and specific inhibition of the breast cancer resistance protein multidrug transporter in vitro and in mouse intestine by a novel analogue of fumitremorgin C.Q44245530
Efficacy of mitoxantrone-loaded albumin microspheres for intratumoral chemotherapy of breast cancerQ44558779
Modulation of the function of the multidrug resistance-linked ATP-binding cassette transporter ABCG2 by the cancer chemopreventive agent curcuminQ80159156
P4510describes a project that usesImageQuantQ112270642
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1562-1571
P577publication date2011-08-17
P1433published inBiochemical PharmacologyQ864229
P1476titleIn vitro and in vivo modulation of ABCG2 by functionalized aurones and structurally related analogs
P478volume82