Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells

scientific article published on March 2009

Down-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3748/WJG.15.1443
P932PMC publication ID2665138
P698PubMed publication ID19322916

P2093author name stringFeng Yan
Chao Pan
Xiao-Min Wang
Quan-Ming Ma
P2860cites workReversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructsQ40092607
Inhibition of the mitogen-activated protein kinase pathway results in the down-regulation of P-glycoproteinQ40109392
Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistanceQ40253550
Modulation of mitogen-activated protein kinase cascades by differentiation-1 protein: acquired drug resistance of hormone independent prostate cancer cellsQ40363338
Regulation of the ERK subgroup of MAP kinase cascades through G protein-coupled receptorsQ41647860
Signal transduction through MAP kinase cascadesQ41750250
Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosisQ44527161
High levels of transglutaminase expression in doxorubicin-resistant human breast carcinoma cellsQ46198386
A 190-kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug-resistant cells and its relationship to the MRP gene.Q52828947
Multiple drug-resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin, or vinblastine show changes in expression of specific proteins.Q52832264
Reversal effect of specific inhibitors of extracellular-signal regulated protein kinase pathway on P-glycoprotein mediated vincristine resistance of L1210 cells.Q53972104
Hepatocellular carcinomaQ93930900
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinasesQ29614338
Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicityQ29614981
Reversal in multidrug resistance by magnetic nanoparticle of Fe3O4 loaded with adriamycin and tetrandrine in K562/A02 leukemic cellsQ33358484
Cellular mechanisms of multidrug resistance of tumor cells.Q33854298
Estimating the world cancer burden: Globocan 2000.Q34518922
Modulation of multidrug resistance efflux pump activity to overcome chemoresistance in cancerQ34524629
ABC multidrug transporters: structure, function and role in chemoresistance.Q34586418
Targeting senescence pathways to reverse drug resistance in cancerQ36032220
MAP kinase pathways: the first twenty yearsQ36094669
Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanomaQ36445971
New therapies for hepatocellular carcinoma.Q36519041
Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.Q36536479
Cellular senescence and cancer treatment.Q36616891
Reversal of P-glycoprotein-mediated multidrug resistance in human sarcoma MES-SA/Dx-5 cells by nonsteroidal anti-inflammatory drugsQ39936488
Calebin-A induces apoptosis and modulates MAPK family activity in drug resistant human gastric cancer cellsQ39962418
Reversal of P-glycoprotein and multidrug resistance-associated protein 1 mediated multidrug resistance in cancer cells by HZ08 Isomers, tetrataisohydroquinolin derivativesQ39976096
Targeting MDR1 gene: synthesis and cellular study of modified daunomycin-triplex-forming oligonucleotide conjugates able to inhibit gene expression in resistant cell lines.Q40009019
The combination of glycyrrhizin and lamivudine can reverse the cisplatin resistance in hepatocellular carcinoma cells through inhibition of multidrug resistance-associated proteins.Q40056366
P4510describes a project that usesImageJQ1659584
P433issue12
P407language of work or nameEnglishQ1860
P921main subjectmultiple drug resistanceQ643839
hepatocellular carcinomaQ1148337
P304page(s)1443-1451
P577publication date2009-03-01
P1433published inWorld Journal of GastroenterologyQ15708885
P1476titleDown-regulation of extracellular signal-regulated kinase 1/2 activity in P-glycoprotein-mediated multidrug resistant hepatocellular carcinoma cells
P478volume15

Reverse relations

cites work (P2860)
Q38680790A 4-Phenoxyphenol Derivative Exerts Inhibitory Effects on Human Hepatocellular Carcinoma Cells through Regulating Autophagy and Apoptosis Accompanied by Downregulating α-Tubulin Expression.
Q36350221Chemosensitization of HepG2 cells by suppression of NF-κB/p65 gene transcription with specific-siRNA
Q36390281Downregulation of δ opioid receptor by RNA interference enhances the sensitivity of BEL/FU drug‑resistant human hepatocellular carcinoma cells to 5‑FU
Q52718771Expression and Functions of Formyl Peptide Receptor 1 in Drug-Resistant Bladder Cancer.
Q35894374Extracellular signal-regulated kinase 1 and 2 in cancer therapy: a focus on hepatocellular carcinoma.
Q46873887IGF2 mRNA binding protein p62/IMP2-2 in hepatocellular carcinoma: antiapoptotic action is independent of IGF2/PI3K signaling
Q39039916Involvement of CUL4A in regulation of multidrug resistance to P-gp substrate drugs in breast cancer cells.
Q41078238MAPK1 of Leishmania donovani modulates antimony susceptibility by downregulating P-glycoprotein efflux pumps
Q37802466Mitogen-activated protein kinases in hepatocellular carcinoma development
Q92838858p75NTR promotes survival of breast cancer resistant cells by regulating Bcl-2/Bax and MAPK pathway

Search more.