Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro

scientific article

Degradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/OR.2016.5230
P932PMC publication ID5355671
P698PubMed publication ID27840996

P2093author name stringHong Liu
Fang Wang
Yong Xie
Li-Wu Fu
Yi-Fan Chen
Xiao-Qin Zhao
Xiao-Kun Wang
Yan-Yan Yan
P2860cites workApatinib (YN968D1) reverses multidrug resistance by inhibiting the efflux function of multiple ATP-binding cassette transportersQ24617999
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
The human ATP-binding cassette (ABC) transporter superfamilyQ28204495
Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport functionQ28475378
Mutations at amino-acid 482 in the ABCG2 gene affect substrate and antagonist specificity.Q33194953
Emodin azide methyl anthraquinone derivative triggers mitochondrial-dependent cell apoptosis involving in caspase-8-mediated Bid cleavageQ33345153
A role for P-glycoprotein in regulating cell deathQ33918906
Axitinib targeted cancer stemlike cells to enhance efficacy of chemotherapeutic drugs via inhibiting the drug transport function of ABCG2.Q34253081
Triterpenoid pristimerin induced HepG2 cells apoptosis through ROS-mediated mitochondrial dysfunctionQ34789068
P-glycoprotein-mediated efflux as a major factor in the variance of absorption and distribution of drugs: modulation of chemotherapy resistanceQ35033926
P-glycoprotein is not involved in pathway of anti-Fas/Fas-induced apoptosis in KBv200 cellsQ35045233
Strategies for reversing drug resistanceQ35567287
Neratinib reverses ATP-binding cassette B1-mediated chemotherapeutic drug resistance in vitro, in vivo, and ex vivo.Q36057369
Mechanism of multidrug resistance in relation to passive membrane permeationQ36082251
Crizotinib (PF-02341066) reverses multidrug resistance in cancer cells by inhibiting the function of P-glycoproteinQ36166672
Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.Q36536479
Medicinal chemistry and pharmacology of genus Tripterygium (Celastraceae)Q36717554
The dihydro-beta-agarofuran sesquiterpenoidsQ36953218
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2Q37119716
Terpenoids: natural inhibitors of NF-kappaB signaling with anti-inflammatory and anticancer potentialQ37178982
Apatinib (YN968D1) enhances the efficacy of conventional chemotherapeutical drugs in side population cells and ABCB1-overexpressing leukemia cellsQ39418811
Blockade of Her2/neu binding to Hsp90 by emodin azide methyl anthraquinone derivative induces proteasomal degradation of Her2/neuQ39495900
Apoptosis Induction in HL-60 Cells and Inhibition of Topoisomerase II by Triterpene CelastrolQ44603146
Pristimerin induces caspase-dependent apoptosis in MDA-MB-231 cells via direct effects on mitochondriaQ46644453
HMBA induces activation of a caspase-independent cell death pathway to overcome P-glycoprotein-mediated multidrug resistanceQ57272492
P-glycoprotein protects leukemia cells against caspase-dependent, but not caspase-independent, cell deathQ57272499
P433issue1
P921main subjectchemotherapyQ974135
P304page(s)31-40
P577publication date2016-11-08
P1433published inOncology ReportsQ7092098
P1476titleDegradation of P-glycoprotein by pristimerin contributes to overcoming ABCB1-mediated chemotherapeutic drug resistance in vitro
P478volume37

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cites work (P2860)
Q46495734ABCB1 Mediates Cabazitaxel-Docetaxel Cross-Resistance in Advanced Prostate Cancer
Q92237902Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review
Q44295635Enhancing conventional chemotherapy drug cisplatin-induced anti-tumor effects on human gastric cancer cells both in vitro and in vivo by Thymoquinone targeting PTEN gene