Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways

scientific article published on 16 December 2014

Noscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1028526240
P356DOI10.1007/S12013-014-0438-Y
P8608Fatcat IDrelease_zibw2pa5u5dznbcbnxnnbqde6u
P698PubMed publication ID25510462

P2093author name stringJianxin Cheng
Wei Shen
Jie Yin
Xiurong Li
Bingfeng Liang
P2860cites workNoscapine induces apoptosis in human glioma cells by an apoptosis-inducing factor-dependent pathwayQ39975147
An IAP-IAP complex inhibits apoptosisQ40541576
Cyclophosphamide and cisplatin compared with paclitaxel and cisplatin in patients with stage III and stage IV ovarian cancerQ40673230
Noscapine inhibits tumor growth with little toxicity to normal tissues or inhibition of immune responsesQ40861714
p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cellsQ42576880
Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpointQ43895739
Antitumor activity of noscapine in human non-small cell lung cancer xenograft modelQ46704388
Expression of signaling molecules associated with apoptosis in human ischemic stroke tissueQ48219003
The "multi" of drug resistance explained by oscillating drug transporters, drug-membrane physical interactions and spatial dimensionality.Q51601160
COX-2 is expressed in human pulmonary, colonic, and mammary tumors.Q53402915
Selection of optimal antisense accessible sites of survivin and its application in treatment of gastric cancerQ31142003
Isolation and functional characterization of single domain antibody modulators of Caspase-3 and apoptosisQ33343611
Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathwayQ33794066
Apoptosis in cancerQ33846227
Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancerQ33851448
Targeting XIAP for the treatment of malignancyQ33991803
Cell death inhibition: keeping caspases in checkQ34210024
A systematic overview of chemotherapy effects in ovarian cancerQ34301239
Estimating the world cancer burden: Globocan 2000.Q34518922
Part I: chemotherapy for epithelial ovarian cancer-treatment at first diagnosisQ34826546
Biomolecular targets for platinum antitumor drugsQ34948778
Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancerQ34982543
The X-linked inhibitor of apoptosis protein (XIAP) is up-regulated in metastatic melanoma, and XIAP cleavage by Phenoxodiol is associated with Carboplatin sensitizationQ35632517
Opium alkaloid noscapine is an antitumor agent that arrests metaphase and induces apoptosis in dividing cellsQ35875879
An update on overcoming MDR1-mediated multidrug resistance in cancer chemotherapyQ36384930
Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.Q36536479
The anti-cancer activity of noscapine: a review.Q37370653
X-linked Inhibitor of Apoptosis: A Chemoresistance Factor or a Hollow PromiseQ37777537
Targeting IAP proteins for therapeutic intervention in cancerQ37980321
Curcumin (diferuloylmethane) down-regulates cigarette smoke-induced NF-kappaB activation through inhibition of IkappaBalpha kinase in human lung epithelial cells: correlation with suppression of COX-2, MMP-9 and cyclin D1.Q38353590
Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapineQ38363629
Celastrol inhibits breast cancer cell invasion via suppression of NF-ĸB-mediated matrix metalloproteinase-9 expressionQ39484899
Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3.Q39945284
P433issue1
P921main subjectapoptotic processQ14599311
ovarian cancerQ172341
cisplatinQ412415
cancer cell lineQ23058136
P304page(s)203-213
P577publication date2014-12-16
P1433published inCell Biochemistry and BiophysicsQ15755135
P1476titleNoscapine Increases the Sensitivity of Drug-Resistant Ovarian Cancer Cell Line SKOV3/DDP to Cisplatin by Regulating Cell Cycle and Activating Apoptotic Pathways
P478volume72

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cites work (P2860)
Q57804591Bitter taste receptors are expressed in human epithelial ovarian and prostate cancers cells and noscapine stimulation impacts cell survival
Q60302272DEBIO 1143, an IAP inhibitor, reverses carboplatin resistance in ovarian cancer cells and triggers apoptotic or necroptotic cell death
Q92689975LncRNA ANRIL affects the sensitivity of ovarian cancer to cisplatin via regulation of let-7a/HMGA2 axis
Q92567882Overexpression of microRNA-195-5p reduces cisplatin resistance and angiogenesis in ovarian cancer by inhibiting the PSAT1-dependent GSK3β/β-catenin signaling pathway
Q37015742Proteasome Inhibitor YSY01A Enhances Cisplatin Cytotoxicity in Cisplatin-Resistant Human Ovarian Cancer Cells
Q47311101Reversal of drug-resistance by noscapine chemo-sensitization in docetaxel resistant triple negative breast cancer
Q26801133The Noscapine Chronicle: A Pharmaco-Historic Biography of the Opiate Alkaloid Family and its Clinical Applications
Q55346269The action mechanism of lncRNA-HOTAIR on the drug resistance of non-small cell lung cancer by regulating Wnt signaling pathway.

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