Pien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway

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Pien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway is …
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scholarly articleQ13442814

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P356DOI10.1155/2014/679436
P932PMC publication ID4253702
P698PubMed publication ID25505925
P5875ResearchGate publication ID269715750

P50authorJiumao LinQ86284775
P2093author name stringJun Peng
Hongwei Chen
Wei Lin
Liya Liu
Thomas J Sferra
Aling Shen
Youqin Chen
P2860cites workThe dilemma and promise of cancer chemoprevention.Q50922961
Pien Tze Huang inhibits tumor cell proliferation and promotes apoptosis via suppressing the STAT3 pathway in a colorectal cancer mouse model.Q54538532
Colorectal cancerQ55924124
Effects of Pien Tze Huang on angiogenesis in vivo and in vitroQ84597562
Global cancer statisticsQ22241238
Molecular origins of cancer: Molecular basis of colorectal cancerQ24617331
The basics of epithelial-mesenchymal transitionQ24652992
Epithelial-mesenchymal transitions in development and diseaseQ27860630
Multidrug resistance in cancer: role of ATP-dependent transportersQ28208049
The snail superfamily of zinc-finger transcription factorsQ28216843
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traitsQ28237197
The role of ABC transporters in drug resistance, metabolism and toxicityQ28283237
Designer TGFβ superfamily ligands with diversified functionalityQ28477811
Increased JNK1 signaling pathway is responsible for ABCG2-mediated multidrug resistance in human colon cancerQ28481849
BCRP/ABCG2 inhibition sensitizes hepatocellular carcinoma cells to sorafenibQ28538126
Complex networks orchestrate epithelial-mesenchymal transitionsQ29547478
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Q29547559
EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancerQ29616360
Molecular requirements for epithelial-mesenchymal transition during tumor progressionQ29618960
TGF-beta-induced epithelial to mesenchymal transitionQ29619820
Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?Q33755906
TGF-beta-induced EMT: mechanisms and implications for fibrotic lung diseaseQ34581113
Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progressionQ34655105
Natural products as leads to anticancer drugsQ34730142
Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?Q34948729
Targeting colon cancer stem cells using a new curcumin analogue, GO-Y030.Q35125616
Epithelial to mesenchymal transition contributes to drug resistance in pancreatic cancerQ35230326
The epithelial-mesenchymal transition (EMT) and colorectal cancer progressionQ36104373
Achieving hypoxia-inducible gene expression in tumorsQ36104383
Molecular biomarkers of colorectal cancer: prognostic and predictive tools for clinical practiceQ36219923
Pien Tze Huang inhibits the proliferation of human colon carcinoma cells by arresting G1/S cell cycle progressionQ36424045
Multidrug resistance: retrospect and prospects in anti-cancer drug treatment.Q36536479
Drug resistance, predictive markers and pharmacogenomics in colorectal cancerQ36594315
Integration of TGF-beta/Smad and Jagged1/Notch signalling in epithelial-to-mesenchymal transitionQ37258903
Role of epithelial-to-mesenchymal transition (EMT) in drug sensitivity and metastasis in bladder cancerQ37655607
Death by design: where curcumin sensitizes drug-resistant tumoursQ38023357
Epithelial mesenchymal transition in colorectal cancer: Seminal role in promoting disease progression and resistance to neoadjuvant therapyQ38043748
Pien Tze Huang inhibits tumor angiogenesis in a mouse model of colorectal cancer via suppression of multiple cellular pathwaysQ39127694
Pien Tze Huang suppresses IL-6-inducible STAT3 activation in human colon carcinoma cells through induction of SOCS3.Q39268105
The BHLH transcription factor DEC1 plays an important role in the epithelial-mesenchymal transition of pancreatic cancerQ39309353
Quantitative shape analysis of chemoresistant colon cancer cells: correlation between morphotype and phenotype.Q39395181
Pien Tze Huang induced apoptosis in human colon cancer HT-29 cells is associated with regulation of the Bcl-2 family and activation of caspase 3.Q39475591
Acquisition of chemoresistance and EMT phenotype is linked with activation of the endothelin A receptor pathway in ovarian carcinoma cells.Q39609746
Drug resistant MCF-7 cells exhibit epithelial-mesenchymal transition gene expression patternQ39617314
Chemoresistance to paclitaxel induces epithelial-mesenchymal transition and enhances metastatic potential for epithelial ovarian carcinoma cells.Q40111238
Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell linesQ40252973
Progress in the adjuvant treatment of colon cancer: has it influenced clinical practice?Q46839608
Development and characterization of gemcitabine-resistant pancreatic tumor cells.Q46971449
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P921main subjectmultiple drug resistanceQ643839
colorectal carcinomaQ25493920
P304page(s)679436
P577publication date2014-11-19
P1433published inEvidence-based Complementary and Alternative MedicineQ5418319
P1476titlePien Tze Huang Overcomes Multidrug Resistance and Epithelial-Mesenchymal Transition in Human Colorectal Carcinoma Cells via Suppression of TGF-β Pathway
P478volume2014

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cites work (P2860)
Q52881957Allyl-isatin suppresses cell viability, induces cell cycle arrest, and promotes cell apoptosis in hepatocellular carcinoma HepG2 cells.
Q64102496Cell division cycle associated 5 promotes colorectal cancer progression by activating the ERK signaling pathway
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Q49843332Herbal formula Huang Qin Ge Gen Tang enhances 5-fluorouracil antitumor activity through modulation of the E2F1/TS pathway
Q38764399Overexpression of DLX2 is associated with poor prognosis and sorafenib resistance in hepatocellular carcinoma.
Q41672448Pien Tze Huang alleviates 5-fluorouracil-induced intestinal mucositis in CT-26 tumor-bearing mice
Q42376437Pien Tze Huang induces apoptosis and inhibits proliferation of 5-fluorouracil-resistant colorectal carcinoma cells via increasing miR-22 expression
Q49277553Pien Tze Huang inhibits the growth of hepatocellular carcinoma cells by upregulating miR-16 expression
Q42376377Pien Tze Huang inhibits the proliferation of colorectal cancer cells by increasing the expression of miR-34c-5p
Q89564046Prediction of hepatic metastasis and relapse in colorectal cancers based on concordance analyses with liver fibrosis scores
Q38725048Salvianolic acid B reverses multidrug resistance in HCT‑8/VCR human colorectal cancer cells by increasing ROS levels
Q41866266The impact of hepatic fibrosis on the incidence of liver metastasis from colorectal cancer.
Q90040165Therapeutic Potential of Pien-Tze-Huang: A Review on Its Chemical Composition, Pharmacology, and Clinical Application

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