Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice

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Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/MT.2009.153
P8608Fatcat IDrelease_sldfpdxyh5cf7iyi6rkrvm7ghi
P932PMC publication ID2835036
P698PubMed publication ID19603006
P5875ResearchGate publication ID26671592

P50authorSang Wan KimQ40350095
Hyung Jin ChoiQ51350269
P2093author name stringJee Hyun An
Seong Yeon Kim
Hyun Jin Sun
Dohee Kim
Chan Soo Shin
Ju Yeon Jung
Jae-Yeon Yang
Sun Wook Cho
Hwa Young Cho
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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Transplanted bone marrow cells localize to fracture callus in a mouse modelQ30310312
Multiple myeloma disrupts the TRANCE/ osteoprotegerin cytokine axis to trigger bone destruction and promote tumor progressionQ33944735
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Osteoporosis prevention, diagnosis, and therapyQ34140339
Trafficking of normal stem cells and metastasis of cancer stem cells involve similar mechanisms: pivotal role of the SDF-1-CXCR4 axisQ34418159
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Meta-analyses of therapies for postmenopausal osteoporosis. III. Meta-analysis of risedronate for the treatment of postmenopausal osteoporosisQ34803295
The essential roles of the chemokine SDF-1 and its receptor CXCR4 in human stem cell homing and repopulation of transplanted immune-deficient NOD/SCID and NOD/SCID/B2m(null) miceQ34926717
Molecular cloning and structure of a pre-B-cell growth-stimulating factorQ35106000
The chemokine SDF-1 is a chemoattractant for human CD34+ hematopoietic progenitor cells and provides a new mechanism to explain the mobilization of CD34+ progenitors to peripheral blood.Q36376700
B lymphocyte chemotaxis regulated in association with microanatomic localization, differentiation state, and B cell receptor engagementQ36400397
Targeting the RANK/RANKL/OPG signaling pathway: a novel approach in the management of osteoporosisQ36801298
Adult mesenchymal stem cells: a pluripotent population with multiple applicationsQ37066506
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Anti-resorptives in the management of osteoporosisQ37333079
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Retroviruses and the study of cell lineage.Q39702779
HGF, SDF-1, and MMP-9 are involved in stress-induced human CD34+ stem cell recruitment to the liverQ39785808
Enhanced functional response to CXCL12/SDF-1 through retroviral overexpression of CXCR4 on M07e cells: implications for hematopoietic stem cell transplantationQ40306487
Bone regeneration in critical size defects by cell-mediated BMP-2 gene transfer: a comparison of adenoviral vectors and liposomesQ40581164
Induction of the chemokine stromal-derived factor-1 following DNA damage improves human stem cell functionQ40736018
Selective transendothelial migration of hematopoietic progenitor cells: a role in homing of progenitor cells.Q40986211
The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.Q41649459
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cellsQ42437094
Presentation of chemokine SDF-1 alpha by fibronectin mediates directed migration of T cells.Q42494257
Calcineurin mediates the calcium-dependent inhibition of adipocyte differentiation in 3T3-L1 cellsQ42809969
Retrovirus-mediated gene transfer of receptor activator of nuclear factor-kappaB-Fc prevents bone loss in ovariectomized miceQ45856973
Bone marrow mesenchymal cells for haemophilia A gene therapy using retroviral vectors with modified long-terminal repeatsQ45858232
Articular cartilage repair by gene therapy using growth factor-producing mesenchymal cellsQ45858451
Overexpression of CXCR4 on human CD34+ progenitors increases their proliferation, migration, and NOD/SCID repopulationQ45874391
Bone development and age-related bone loss in male C57BL/6J miceQ46286440
Mesenchymal stem cells from ischemic heart disease patients improve left ventricular function after acute myocardial infarction.Q50672733
Efficacy of bone marrow-derived stem cells in strengthening osteoporotic bone in a rabbit model.Q50720359
The role of bone marrow-derived cells in bone fracture repair in a green fluorescent protein chimeric mouse model.Q50770703
Regulation of CXCR4 expression in human mesenchymal stem cells by cytokine treatment: role in homing efficiency in NOD/SCID mice.Q50963245
Genetic variability in adult bone density among inbred strains of mice.Q52201749
Pre-treatment of mesenchymal stem cells with a combination of growth factors enhances gap junction formation, cytoprotective effect on cardiomyocytes, and therapeutic efficacy for myocardial infarction.Q53547964
Patients' voices: the powerful sound in the stem cell debateQ73479404
Dependence of human stem cell engraftment and repopulation of NOD/SCID mice on CXCR4Q77952550
Soluble receptor activator of nuclear factor kappaB Fc diminishes prostate cancer progression in boneQ79317200
Preconditioning enhances cell survival and differentiation of stem cells during transplantation in infarcted myocardiumQ79842788
Mesenchymal stem cells participate in angiogenesis and improve heart function in rat model of myocardial ischemia with reperfusionQ79862803
Targeted migration of mesenchymal stem cells modified with CXCR4 gene to infarcted myocardium improves cardiac performanceQ80641442
Nonprimate animal models of menopause: workshop reportQ93929231
P433issue11
P921main subjectmesenchymal stem cellQ1922379
overexpressionQ61643320
P304page(s)1979-1987
P577publication date2009-07-14
P1433published inMolecular TherapyQ15762400
P1476titleTransplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice
P478volume17

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cites work (P2860)
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