scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1081/DMR-100101938 |
P698 | PubMed publication ID | 10461543 |
P2093 | author name string | Ludolph AC | |
Münch C | |||
P2860 | cites work | Aggregation and Motor Neuron Toxicity of an ALS-Linked SOD1 Mutant Independent from Wild-Type SOD1 | Q22299419 |
Spastic paraplegia and OXPHOS impairment caused by mutations in paraplegin, a nuclear-encoded mitochondrial metalloprotease | Q24309083 | ||
Excitatory amino acid transporter 5, a retinal glutamate transporter coupled to a chloride conductance | Q24313586 | ||
An excitatory amino-acid transporter with properties of a ligand-gated chloride channel | Q24323343 | ||
Structure, expression, and functional analysis of a Na(+)-dependent glutamate/aspartate transporter from rat brain | Q24563212 | ||
Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase | Q27731976 | ||
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis | Q28131805 | ||
Cloning and expression of a rat brain L-glutamate transporter | Q28203723 | ||
Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis | Q28267385 | ||
Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis | Q28270636 | ||
RNA editing in brain controls a determinant of ion flow in glutamate-gated channels | Q28279138 | ||
Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase | Q28284593 | ||
Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury | Q28511628 | ||
Transgenic mice with increased Cu/Zn-superoxide dismutase activity: animal model of dosage effects in Down syndrome | Q28592168 | ||
Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1 | Q28592689 | ||
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation | Q29547561 | ||
Superoxide radical and superoxide dismutases | Q29614204 | ||
Cloned glutamate receptors | Q29619950 | ||
Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate | Q29620128 | ||
Tissue specific variants of glutamate transporter GLT-1. | Q30090179 | ||
Comparison of sporadic and familial disease amongst 580 cases of motor neuron disease | Q33631319 | ||
Primary structure and functional characterization of a high-affinity glutamate transporter | Q34205379 | ||
Brain lesions in an infant rhesus monkey treated with monsodium glutamate | Q34240164 | ||
Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis | Q34300016 | ||
Glutamate neurotoxicity and diseases of the nervous system | Q34560997 | ||
Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons | Q34667159 | ||
Benefit of vitamin E, riluzole, and gabapentin in a transgenic model of familial amyotrophic lateral sclerosis | Q34736976 | ||
Alternative excitotoxic hypotheses | Q35227246 | ||
Are human neurodegenerative disorders linked to environmental chemicals with excitotoxic properties? | Q35230778 | ||
Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses? | Q35254212 | ||
Superoxide dismutase 1 with mutations linked to familial amyotrophic lateral sclerosis possesses significant activity | Q35693516 | ||
Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity | Q36420529 | ||
A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide | Q37550536 | ||
Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions | Q37688651 | ||
Reduced postischemic expression of a glial glutamate transporter, GLT1, in the rat hippocampus | Q38300706 | ||
Genomic organization of the human excitatory amino acid transporter gene GLT-1. | Q38348472 | ||
Excitotoxicity, energy metabolism and neurodegeneration | Q40713305 | ||
Superoxide dismutase in familial amyotrophic lateral sclerosis: models for gain of function | Q41111012 | ||
Toxic models of upper motor neuron disease | Q41194822 | ||
Mitochondria, free radicals, and neurodegeneration | Q41235574 | ||
Ischemia-induced neuronal apoptosis | Q41235586 | ||
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). | Q41351491 | ||
The EAAT2 (GLT-1) gene in motor neuron disease: absence of mutations in amyotrophic lateral sclerosis and a point mutation in patients with hereditary spastic paraplegia | Q41843474 | ||
Lathyrism: evidence for role of the neuroexcitatory aminoacid BOAA. | Q42201775 | ||
Splicing of the glutamate transporter EAAT2: a candidate gene of amyotrophic lateral sclerosis | Q42912839 | ||
Excitotoxic disorders | Q44405122 | ||
Decreased glutamate transport by the brain and spinal cord in amyotrophic lateral sclerosis | Q45291121 | ||
The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q45882912 | ||
Amyloid protein precursor stimulates excitatory amino acid transport. Implications for roles in neuroprotection and pathogenesis | Q46162628 | ||
Deficient glutamate transport is associated with neurodegeneration in Alzheimer's disease | Q46372282 | ||
5'-heterogeneity of the human excitatory amino acid transporter cDNA EAAT2 (GLT-1). | Q47959438 | ||
Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice | Q47996542 | ||
Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene | Q48045866 | ||
Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease | Q48241885 | ||
Neurological dysfunctions in mice expressing different levels of the Q/R site-unedited AMPAR subunit GluR-B. | Q48242571 | ||
Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients | Q48466261 | ||
Alternative splicing of the glutamate transporter EAAT2 (GLT-1). | Q48510470 | ||
Studies of the coding region of the neuronal glutamate transporter gene in amyotrophic lateral sclerosis. | Q53011672 | ||
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria | Q54965159 | ||
Relative abundance of subunit mRNAs determines gating and Ca2+ permeability of AMPA receptors in principal neurons and interneurons in rat CNS | Q57378339 | ||
Immunohistochemical mapping of calcium-binding protein immunoreactivity in the rat central nervous system | Q70337731 | ||
Oxidative stress in neurodegenerative diseases | Q71306903 | ||
Motor neuron degeneration induced by excitotoxin agonists has features in common with those seen in the SOD-1 transgenic mouse model of amyotrophic lateral sclerosis | Q71483679 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | neurotoxicity | Q3338704 |
P304 | page(s) | 619-634 | |
P577 | publication date | 1999-08-01 | |
P1433 | published in | Drug Metabolism Reviews | Q5308857 |
P1476 | title | Neurotoxic mechanisms of degeneration in motor neuron diseases | |
P478 | volume | 31 |
Q49047132 | Calcineurin A and calbindin immunoreactivity in the spinal cord of G93A superoxide dismutase transgenic mice |
Q39747906 | Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage |
Q28190140 | Glutamate uptake |
Q44807720 | Physiopathology of ALS: therapeutic approach |
Q24681228 | Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis |