| scholarly article | Q13442814 |
| P50 | author | Ellora Sen | Q62607204 |
| P2093 | author name string | R Ghildiyal | |
| D Dixit | |||
| N P Anto | |||
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| The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase | Q33741157 | ||
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| Pyruvate kinase M2 expression, but not pyruvate kinase activity, is up-regulated in a grade-specific manner in human glioma | Q34603709 | ||
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| Regulation of the mammalian selenoprotein thioredoxin reductase 1 in relation to cellular phenotype, growth, and signaling events. | Q35673955 | ||
| The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation | Q35681981 | ||
| DNA damage induces reactive oxygen species generation through the H2AX-Nox1/Rac1 pathway. | Q35723863 | ||
| Chaetocin: a promising new antimyeloma agent with in vitro and in vivo activity mediated via imposition of oxidative stress | Q35750893 | ||
| Inhibition of Casein kinase-2 induces p53-dependent cell cycle arrest and sensitizes glioblastoma cells to tumor necrosis factor (TNFα)-induced apoptosis through SIRT1 inhibition. | Q35783593 | ||
| Quantitative proteomics profiling of murine mammary gland cells unravels impact of annexin-1 on DNA damage response, cell adhesion, and migration | Q36144166 | ||
| Histone 3 lysine 9 trimethylation is differentially associated with isocitrate dehydrogenase mutations in oligodendrogliomas and high-grade astrocytomas | Q36737930 | ||
| ATM-NFκB axis-driven TIGAR regulates sensitivity of glioma cells to radiomimetics in the presence of TNFα. | Q36907054 | ||
| ATM kinase enables the functional axis of YAP, PML and p53 to ameliorate loss of Werner protein-mediated oncogenic senescence. | Q37219985 | ||
| Targeting metabolic remodeling in glioblastoma multiforme | Q37840941 | ||
| ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome | Q38307931 | ||
| Up-regulation of endogenous PML induced by a combination of interferon-beta and temozolomide enhances p73/YAP-mediated apoptosis in glioblastoma | Q38325750 | ||
| Guggulsterone sensitizes glioblastoma cells to Sonic hedgehog inhibitor SANT-1 induced apoptosis in a Ras/NFκB dependent manner | Q39172548 | ||
| Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells | Q39404940 | ||
| Involvement of TNFα-induced TLR4-NF-κB and TLR4-HIF-1α feed-forward loops in the regulation of inflammatory responses in glioma. | Q39480423 | ||
| JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis | Q39583499 | ||
| Hexokinase 2 is a key mediator of aerobic glycolysis and promotes tumor growth in human glioblastoma multiforme | Q39606772 | ||
| Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells | Q39801156 | ||
| Involvement of ATM-mediated Chk1/2 and JNK kinase signaling activation in HKH40A-induced cell growth inhibition. | Q39837434 | ||
| Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation. | Q39857760 | ||
| Kaempferol induces apoptosis in glioblastoma cells through oxidative stress | Q40079278 | ||
| Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. | Q40234453 | ||
| Chaetocin is a nonspecific inhibitor of histone lysine methyltransferases | Q42712897 | ||
| Anti-leukemia activity of chaetocin via death receptor-dependent apoptosis and dual modulation of the histone methyl-transferase SUV39H1. | Q42726197 | ||
| Identification of a specific inhibitor of the histone methyltransferase SU(VAR)3-9. | Q46890994 | ||
| Oncrasin targets the JNK-NF-κB axis to sensitize glioma cells to TNFα-induced apoptosis | Q48308236 | ||
| P275 | copyright license | Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported | Q19125045 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P921 | main subject | apoptotic process | Q14599311 |
| P304 | page(s) | e1212 | |
| P577 | publication date | 2014-05-08 | |
| P1433 | published in | Cell Death and Disease | Q2197222 |
| P1476 | title | Chaetocin-induced ROS-mediated apoptosis involves ATM-YAP1 axis and JNK-dependent inhibition of glucose metabolism | |
| P478 | volume | 5 |
| Q38266299 | A balancing act: orchestrating amino-truncated and full-length p73 variants as decisive factors in cancer progression |
| Q38784313 | CK2 inhibition induced PDK4-AMPK axis regulates metabolic adaptation and survival responses in glioma. |
| Q33574636 | Chaetocin induces apoptosis in human melanoma cells through the generation of reactive oxygen species and the intrinsic mitochondrial pathway, and exerts its anti-tumor activity in vivo |
| Q92684203 | Chaetocin induces caspase-dependent apoptosis in ovarian cancer cells via the generation of reactive oxygen species |
| Q38722535 | Chaetocin reactivates the lytic replication of Epstein-Barr virus from latency via reactive oxygen species |
| Q90383433 | Double the Chemistry, Double the Fun: Structural Diversity and Biological Activity of Marine-Derived Diketopiperazine Dimers |
| Q64975240 | Drugs Targeting Epigenetic Modifications and Plausible Therapeutic Strategies Against Colorectal Cancer. |
| Q38773490 | Effect of chaetocin on renal cell carcinoma cells and cytokine-induced killer cells |
| Q50134165 | Hexokinase 2 and nuclear factor erythroid 2-related factor 2 transcriptionally coactivate xanthine oxidoreductase expression in stressed glioma cells. |
| Q46497868 | Hydrogen-rich water regulates effects of ROS balance on morphology, growth and secondary metabolism via glutathione peroxidase in Ganoderma lucidum |
| Q41193099 | Individual Cytokines Modulate the Neurological Symptoms of ATM Deficiency in a Region Specific Manner(1,2,3) |
| Q37716657 | Inhibition of cancer antioxidant defense by natural compounds. |
| Q41320850 | Interaction of TIM4 and TIM3 induces T helper 1 cell apoptosis |
| Q48735294 | JNK Activation Contributes to Oxidative Stress-Induced Parthanatos in Glioma Cells via Increase of Intracellular ROS Production |
| Q91738229 | Local Tumor Ischemia-Reperfusion Mediated By Ultrasound-Targeted Microbubble Destruction Enhances The Anti-Tumor Efficacy Of Doxorubicin Chemotherapy |
| Q30840255 | Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine |
| Q39297355 | Metabolic Reprogramming in Glioma. |
| Q37626226 | Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity |
| Q37030289 | Nrf2-driven TERT regulates pentose phosphate pathway in glioblastoma |
| Q50053003 | PD-L1 confers resistance to EGFR mutation-independent tyrosine kinase inhibitors in non-small cell lung cancer via upregulation of YAP1 expression |
| Q37164423 | PPARγ regulated CIDEA affects pro-apoptotic responses in glioblastoma |
| Q90929522 | ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin |
| Q47765417 | Reciprocal role of SIRT6 and Hexokinase 2 in the regulation of autophagy driven monocyte differentiation. |
| Q38370200 | Role of Yes-associated protein 1 in gliomas: pathologic and therapeutic aspects |
| Q36494204 | Sequence Kernel Association Test of Multiple Continuous Phenotypes |
| Q96302592 | Sestrin2 inhibits YAP activation and negatively regulates corneal epithelial cell proliferation |
| Q61480419 | Synthesis of New Diketopiperazines, Thiolation to Thiodiketopiperazines, and Examination of Their ROS-Generating Properties |
| Q38949348 | TGF-β-induced hCG-β regulates redox homeostasis in glioma cells. |
| Q90345239 | The Crosstalk Between Hippo-YAP Pathway and Innate Immunity |
| Q61306968 | The ERK and JNK pathways in the regulation of metabolic reprogramming |
| Q33588163 | The YAP1/SIX2 axis is required for DDX3-mediated tumor aggressiveness and cetuximab resistance in KRAS-wild-type colorectal cancer |
| Q38793061 | The anticancer effect of chaetocin is enhanced by inhibition of autophagy. |
| Q91473421 | The fungal metabolite chaetocin is a sensitizer for pro-apoptotic therapies in glioblastoma |
| Q39169719 | The role of STIM1 in the Cr(vi)-induced [Ca(2+)]i increase and cell injury in L-02 hepatocytes |
| Q35753464 | Tricyclic Analogues of Epidithiodioxopiperazine Alkaloids with Promising In Vitro and In Vivo Antitumor Activity |
| Q36288376 | Uniformity under in vitro conditions: Changes in the phenotype of cancer cell lines derived from different medulloblastoma subgroups |
| Q59794400 | [Molecular Mechanism of Different Signaling Pathways in Regulating PD-L1 Expression in EGFR Mutated Lung Adenocarcinoma] |
| Q38843848 | miR-429 inhibits glioma invasion through BMK1 suppression |
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