Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers

scientific article published on September 10, 2010

Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1667/RR2273.1
P953full work available at URLhttps://europepmc.org/articles/pmc3529744?pdf=render
http://www.bioone.org/bioone/?request=get-abstract&issn=0033-7587&volume=174&issue=05&page=0574
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20954859/?tool=EBI
https://europepmc.org/articles/PMC3529744
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20954859/pdf/?tool=EBI
https://europepmc.org/articles/PMC3529744?pdf=render
https://doi.org/10.1667/rr2273.1
P932PMC publication ID3529744
P698PubMed publication ID20954859

P50authorJames W JacobbergerQ60656052
Tomas RadivoyevitchQ52352675
P2093author name stringJohn Pink
Song-Mao Chiu
Tammy Stefan
Timothy J. Kinsella
Charles A. Kunos
P2860cites workp53 sends nucleotides to repair DNA.Q53412450
R: A Language for Data Analysis and GraphicsQ56268347
Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunitsQ69900353
Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesisQ72393641
Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancerQ77321076
A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damageQ28138556
Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunitsQ28180311
The human ribonucleotide reductase subunit hRRM2 complements p53R2 in response to UV-induced DNA repair in cells with mutant p53Q28212918
Cell-cycle checkpoints and cancerQ28293996
Structure and function of the radical enzyme ribonucleotide reductaseQ28619961
Structure, function, and mechanism of ribonucleotide reductasesQ30164061
Modulating radiation resistance by inhibiting ribonucleotide reductase in cancers with virally or mutationally silenced p53 proteinQ33638420
Phase I trial of pelvic radiation, weekly cisplatin, and 3-aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, NSC #663249) for locally advanced cervical cancerQ33658330
Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence, and differentiation.Q34163730
p53 point mutation in HPV negative human cervical carcinoma cell linesQ38335537
Kinetics of H2AX phosphorylation after exposure to cisplatinQ39947163
Phosphorylation of histone H2AX as a measure of radiosensitivityQ40594249
Overexpression of the R2 subunit of ribonucleotide reductase in human nasopharyngeal cancer cells reduces radiosensitivityQ40635744
Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells.Q41038705
Global Comparison of Radiation and Chemotherapy Dose-Response Curves with a Test for InteractionQ41540078
Regulation of mammalian ribonucleotide reduction and dNTP pools after DNA damage and in resting cellsQ42489935
Tumor antigen and human chorionic gonadotropin in CaSki cells: a new epidermoid cervical cancer cell lineQ42802859
Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocksQ42803744
Deoxyribonucleoside kinases: two enzyme families catalyze the same reactionQ46492978
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcervix uterine cancerQ160105
P304page(s)574-581
P577publication date2010-09-10
P1433published inRadiation ResearchQ2446628
P1476titleRibonucleotide reductase inhibition enhances chemoradiosensitivity of human cervical cancers
Ribonucleotide Reductase Inhibition Enhances Chemoradiosensitivity of Human Cervical Cancers
P478volume174

Reverse relations

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Q34015533Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistance
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