Differences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats

scientific article

Differences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/HEP.23391
P932PMC publication ID2840074
P698PubMed publication ID20069651
P5875ResearchGate publication ID41002263

P2093author name stringNeil Kaplowitz
Cheng Ji
Masao Shinohara
P2860cites workHomocysteine and cardiovascular diseaseQ28265188
Homocysteine-induced endoplasmic reticulum stress causes dysregulation of the cholesterol and triglyceride biosynthetic pathwaysQ28365886
Mice deficient in cystathionine beta-synthase: animal models for mild and severe homocyst(e)inemiaQ28506932
Regulation of hepatic lipogenesis by the transcription factor XBP1Q28507784
Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid depositionQ31958453
Homocysteine: a history in progressQ34002021
Pathways and regulation of homocysteine metabolism in mammalsQ34049280
Role of CHOP in hepatic apoptosis in the murine model of intragastric ethanol feedingQ34524224
Hyperhomocysteinemia, endoplasmic reticulum stress, and alcoholic liver injuryQ35799626
The central nervous system in animal models of hyperhomocysteinemiaQ36235812
Inborn errors of sulfur-containing amino acid metabolismQ36479642
Dissection of endoplasmic reticulum stress signaling in alcoholic and non-alcoholic liver injuryQ36800154
Endoplasmic reticulum stress and liver injuryQ36989688
Effect of transgenic extrahepatic expression of betaine-homocysteine methyltransferase on alcohol or homocysteine-induced fatty liverQ37001200
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytesQ37097149
Methionine metabolism and liver diseaseQ37106480
Hyperhomocysteinemia due to cystathionine beta synthase deficiency induces dysregulation of genes involved in hepatic lipid homeostasis in miceQ38308736
Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosineQ38310001
Betaine decreases hyperhomocysteinemia, endoplasmic reticulum stress, and liver injury in alcohol-fed miceQ38354947
Dephosphorylation of translation initiation factor 2alpha enhances glucose tolerance and attenuates hepatosteatosis in miceQ39975807
Role of TNF-alpha in ethanol-induced hyperhomocysteinemia and murine alcoholic liver injuryQ45059661
Predominant role of sterol response element binding proteins (SREBP) lipogenic pathways in hepatic steatosis in the murine intragastric ethanol feeding modelQ46243875
Intragastric ethanol infusion model in rodentsQ46679808
ER stress and lipogenesis: a slippery slope toward hepatic steatosis.Q51944768
The effect of methotrexate on homocysteine methylating agents in rat liver.Q54312961
Hepatic transmethylation and blood alcohol levelsQ67954969
Methionine metabolism in mammals: Kinetic study of betaine-homocysteine methyltransferaseQ69410524
Methionine metabolism in mammals. Distribution of homocysteine between competing pathwaysQ71431037
Betaine aldehyde, betaine, and choline levels in rat livers during ethanol metabolismQ73186745
Methionine metabolism in liver diseasesQ73321518
P4510describes a project that usesImageJQ1659584
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectendoplasmic reticulumQ79927
P1104number of pages10
P304page(s)796-805
P577publication date2010-03-01
P1433published inHepatologyQ15724398
P1476titleDifferences in betaine-homocysteine methyltransferase expression, endoplasmic reticulum stress response, and liver injury between alcohol-fed mice and rats
P478volume51

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cites work (P2860)
Q28539163Activating transcription factor 6 is necessary and sufficient for alcoholic fatty liver disease in zebrafish
Q35478792Alcohol disrupts endoplasmic reticulum function and protein secretion in hepatocytes
Q53152230Betaine homocysteine methyltransferase (BHMT) as a specific and sensitive blood marker for acute liver injury.
Q55016760Betaine in Inflammation: Mechanistic Aspects and Applications.
Q43484224Chronic ethanol consumption alters mammalian gastrointestinal content metabolites.
Q35626784Comparative metabolomic and genomic analyses of TCDD-elicited metabolic disruption in mouse and rat liver
Q46213703Dealing with stress
Q36375263Differences in Akt signaling and metabolism gene expression in the right heart, intraventricular septum and left heart of rodents
Q41107415Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis.
Q36452001Dynamic adaptation of liver mitochondria to chronic alcohol feeding in mice: biogenesis, remodeling, and functional alterations.
Q36442525Experimental models of liver fibrosis
Q48204043Folate Protects Hepatocytes of Hyperhomocysteinemia Mice From Apoptosis via Cystic Fibrosis Transmembrane Conductance Regulator (CFTR)-Activated Endoplasmic Reticulum Stress
Q90676288Hepatoprotective effects of betaine on liver damages followed by myocardial infarction
Q46592703Hepatoprotective effects of lycopene on liver enzymes involved in methionine and xenobiotic metabolism in hyperhomocysteinemic rats
Q43114211In Vivo Acute on Chronic Ethanol Effects in Liver: A Mouse Model Exhibiting Exacerbated Injury, Altered Metabolic and Epigenetic Responses
Q35954753Interstrain differences in liver injury and one-carbon metabolism in alcohol-fed mice
Q36070165Investigation of chronic alcohol consumption in rodents via ultra-high-performance liquid chromatography-mass spectrometry based metabolite profiling
Q34187979Involvement and mechanism of DGAT2 upregulation in the pathogenesis of alcoholic fatty liver disease
Q41825121Liver-specific loss of glucose-regulated protein 78 perturbs the unfolded protein response and exacerbates a spectrum of liver diseases in mice
Q38898700Mechanisms of alcohol-induced endoplasmic reticulum stress and organ injuries
Q34553347Metabonomic Investigation of Liver Profiles of Nonpolar Metabolites Obtained from Alcohol-Dosed Rats and Mice Using High Mass Accuracy MSn Analysis
Q46189389Mitochondrial remodeling in the liver following chronic alcohol feeding to rats
Q33608283New Insights into the Pathogenesis of Alcohol-Induced ER Stress and Liver Diseases
Q27026399New advances in molecular mechanisms and emerging therapeutic targets in alcoholic liver diseases
Q38102732Plant-based foods as a source of lipotropes for human nutrition: a survey of in vivo studies
Q48169442Protective roles of hepatic gamma-aminobutyric acid signaling in acute ethanol exposure-induced liver injury
Q34860549The contribution of endoplasmic reticulum stress to liver diseases

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