MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine

scientific article

MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1530/ERC-16-0525
P932PMC publication ID5446589
P698PubMed publication ID28289080

P2093author name stringPriyanka Agarwal
Neil A Bhowmick
Bethany Smith
P2860cites workThe Drosha-DGCR8 complex in primary microRNA processingQ24318603
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATPQ24539076
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemiaQ24539231
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early deathQ24563654
Transforming growth factor-beta1 mediates epithelial to mesenchymal transdifferentiation through a RhoA-dependent mechanismQ24600173
Characterization of extracellular circulating microRNAQ24603537
The ZEB/miR-200 feedback loop--a motor of cellular plasticity in development and cancer?Q24617121
The microRNA miR-34a inhibits prostate cancer stem cells and metastasis by directly repressing CD44Q24617130
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MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoAQ24648090
miR-34a repression of SIRT1 regulates apoptosisQ24652720
The basics of epithelial-mesenchymal transitionQ24652992
MicroRNA-155 is induced during the macrophage inflammatory responseQ24683841
Role of EMT in Metastasis and Therapy ResistanceQ26772923
RAS-MAPK pathway epigenetic activation in cancer: miRNAs in actionQ26773479
RAS is regulated by the let-7 microRNA familyQ27860522
Epithelial-mesenchymal transitions in development and diseaseQ27860630
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14Q27860849
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Tumour invasion and metastasis initiated by microRNA-10b in breast cancerQ28131829
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translationQ28281118
A microRNA component of the p53 tumour suppressor networkQ28305330
Let-7 Sensitizes KRAS Mutant Tumor Cells to ChemotherapyQ28547017
Carboplatin with Decitabine Therapy, in Recurrent Platinum Resistant Ovarian Cancer, Alters Circulating miRNAs Concentrations: A Pilot StudyQ28550381
SMAD proteins control DROSHA-mediated microRNA maturationQ28941771
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Docetaxel and estramustine compared with mitoxantrone and prednisone for advanced refractory prostate cancerQ29616123
Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancerQ29616218
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epitheliaQ29618875
Zeb1 and Snail1 engage miR-200f transcriptional and epigenetic regulation during EMTQ59123125
Investigation of miR-21, miR-141, and miR-221 in blood circulation of patients with prostate cancerQ83316012
Circulating miRNAs are correlated with tumor progression in prostate cancerQ84232903
MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-Snail1 pathway in melanomaQ37646533
MicroRNA-21 promotes TGF-β1-induced epithelial-mesenchymal transition in gastric cancer through up-regulating PTEN expressionQ37687107
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Stellate cells and the development of liver cancer: therapeutic potential of targeting the stromaQ38188317
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MicroRNA-130a-mediated down-regulation of Smad4 contributes to reduced sensitivity to TGF-β1 stimulation in granulocytic precursorsQ38330822
MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer.Q38332381
Crosstalk between TGF-β signaling and miRNAs in breast cancer metastasisQ38772722
The translational potential of microRNAs as biofluid markers of urological tumours.Q38800426
MicroRNAs as regulatory elements in immune system logicQ38819277
MicroRNA-16 suppresses epithelial-mesenchymal transition‑related gene expression in human gliomaQ38954519
Identification of miR-133b and RB1CC1 as independent predictors for biochemical recurrence and potential therapeutic targets for prostate cancer.Q39017152
miR-208-induced epithelial to mesenchymal transition of pancreatic cancer cells promotes cell metastasis and invasionQ39017823
T cells redirected to EphA2 for the immunotherapy of glioblastomaQ39258646
MiR-34a inhibits proliferation and migration of breast cancer through down-regulation of Bcl-2 and SIRT1.Q39343253
Smad3 regulates E-cadherin via miRNA-200 pathwayQ39454247
Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancerQ39550421
miR-9 and miR-200 Regulate PDGFRβ-Mediated Endothelial Differentiation of Tumor Cells in Triple-Negative Breast Cancer.Q39612245
MicroRNA 483-3p suppresses the expression of DPC4/Smad4 in pancreatic cancerQ39626698
MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}.Q39637718
Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA deliveryQ40390348
Carcinoma-associated fibroblasts direct tumor progression of initiated human prostatic epitheliumQ40923257
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cellsQ41164260
Metastatic ability: adapting to a tissue site unseenQ41548032
Role for stromal heterogeneity in prostate tumorigenesisQ41760480
Role of miRNA let-7 and its major targets in prostate cancer.Q41890041
Dysregulation of circulating microRNAs and prediction of aggressive prostate cancerQ42112822
Phosphatidylinositol 3-kinase function is required for transforming growth factor beta-mediated epithelial to mesenchymal transition and cell migration.Q42492769
MiRNA expression analysis of cancer-associated fibroblasts and normal fibroblasts in breast cancer.Q44031786
miR-148b functions as a tumor suppressor in pancreatic cancer by targeting AMPKα1.Q44213136
Integrin beta 1 signaling is necessary for transforming growth factor-beta activation of p38MAPK and epithelial plasticityQ45405811
Cancer stem-like cell marker CD44 promotes bone metastases by enhancing tumorigenicity, cell motility, and hyaluronan productionQ46409730
Induction of heart valve lesions by small-molecule ALK5 inhibitors.Q51423313
Architecture of a validated microRNA::target interaction.Q52062047
Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.Q53098125
Downregulation of microRNAs directs the EMT and invasive potential of anaplastic thyroid carcinomas.Q54672329
MiRNA-621 sensitizes breast cancer to chemotherapy by suppressing FBXO11 and enhancing p53 activity.Q36157026
TGF-β-miR-34a-CCL22 signaling-induced Treg cell recruitment promotes venous metastases of HBV-positive hepatocellular carcinoma.Q36237549
Comment on "MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction"Q36409311
MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancerQ36430771
Restoration of miR-200c to ovarian cancer reduces tumor burden and increases sensitivity to paclitaxelQ36460311
MYC is activated by USP2a-mediated modulation of microRNAs in prostate cancerQ36469814
Targeted delivery of paclitaxel to EphA2-expressing cancer cellsQ36511070
The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN.Q36536455
Integrated gene and miRNA expression analysis of prostate cancer associated fibroblasts supports a prominent role for interleukin-6 in fibroblast activationQ36544603
miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer.Q36586444
Tumour exosome integrins determine organotropic metastasis.Q36677568
Stromal miR-200s contribute to breast cancer cell invasion through CAF activation and ECM remodelingQ36751290
Exosomal transfer of stroma-derived miR21 confers paclitaxel resistance in ovarian cancer cells through targeting APAF1.Q36764656
The metastasis-promoting roles of tumor-associated immune cellsQ36972016
The Dual Role of TGFβ in Human Cancer: From Tumor Suppression to Cancer MetastasisQ36985643
Role of TGF-β and the tumor microenvironment during mammary tumorigenesisQ37044604
Therapeutic evaluation of microRNA-15a and microRNA-16 in ovarian cancerQ37046805
Dicer, Drosha, and outcomes in patients with ovarian cancerQ37262584
Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance.Q37284266
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.Q37328435
Therapeutic synergy between microRNA and siRNA in ovarian cancer treatmentQ37373640
Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancerQ37388344
TGF-β1 modulates microglial phenotype and promotes recovery after intracerebral hemorrhageQ37544957
A collagen-remodeling gene signature regulated by TGF-β signaling is associated with metastasis and poor survival in serous ovarian cancerQ37624417
MiR-21/Smad 7 signaling determines TGF-β1-induced CAF formationQ30418688
MicroRNA-145 regulates chondrogenic differentiation of mesenchymal stem cells by targeting Sox9.Q31026166
Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancerQ33572313
Circulating microRNAs are associated with docetaxel chemotherapy outcome in castration-resistant prostate cancerQ33613644
Frequent downregulation of miR-34 family in human ovarian cancersQ33658229
miR-10b targets Tiam1: implications for Rac activation and carcinoma migrationQ33966873
A reciprocal role of prostate cancer on stromal DNA damageQ34000472
MiR-34a expression has an effect for lower risk of metastasis and associates with expression patterns predicting clinical outcome in breast cancerQ34079217
Molecular biology. Glimpses of a tiny RNA worldQ34099353
Functional MicroRNA Is Transferred between Glioma CellsQ34137987
MicroRNA profile indicates downregulation of the TGFβ pathway in sporadic non-functioning pituitary adenomasQ34148960
Deregulation of miR-519a, 153, and 485-5p and its clinicopathological relevance in ovarian epithelial tumoursQ34150301
Exosome-mediated transfer of miR-133b from multipotent mesenchymal stromal cells to neural cells contributes to neurite outgrowthQ34275817
The mechanics of miRNA-mediated gene silencing: a look under the hood of miRISC.Q34278940
Mechanisms of control of microRNA biogenesis.Q34310633
microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actionsQ34375528
Clinical development success rates for investigational drugsQ34396786
miR-200a Prevents renal fibrogenesis through repression of TGF-β2 expressionQ34448719
Cell-type-specific signatures of microRNAs on target mRNA expressionQ34479693
MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferationQ34506870
Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancerQ34526484
TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrestQ34789115
New class of microRNA targets containing simultaneous 5'-UTR and 3'-UTR interaction sitesQ34972173
Genetic analysis of the mammalian transforming growth factor-beta superfamilyQ35017076
Spatiotemporal dynamics of microRNA during epithelial collective cell migrationQ35032629
Anti-EphA2 antibodies decrease EphA2 protein levels in murine CT26 colorectal and human MDA-231 breast tumors but do not inhibit tumor growthQ35060278
MicroRNA-208a increases myocardial fibrosis via endoglin in volume overloading heartQ35083325
The biological functions of miRNAs: lessons from in vivo studiesQ35132364
Concurrent Targeting of KRAS and AKT by MiR-4689 Is a Novel Treatment Against Mutant KRAS Colorectal CancerQ35161368
Stromal fibroblast-derived miR-409 promotes epithelial-to-mesenchymal transition and prostate tumorigenesisQ35213732
Systemic miRNA-195 differentiates breast cancer from other malignancies and is a potential biomarker for detecting noninvasive and early stage diseaseQ35584190
MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac DysfunctionQ35763090
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failureQ35964249
The miR-200 family and its targets regulate type II cell differentiation in human fetal lung.Q36049885
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectprecision medicineQ17075943
breast neoplasmQ23929670
microRNAQ310899
ovarian neoplasmQ11793790
prostate neoplasmQ56014511
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)R157-R172
P577publication date2017-03-13
2017-05-01
P1433published inEndocrine-Related CancerQ3054004
P1476titleMicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine
P478volume24

Reverse relations

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