MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction

scientific article published on 7 June 2015

MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1155/2015/597032
P932PMC publication ID4475537
P698PubMed publication ID26137188
P5875ResearchGate publication ID279153717

P2093author name stringKunwu Yu
Hasahya Tony
Zeng Qiutang
P2860cites workDoxorubicin induces apoptosis in Jurkat cells by mitochondria-dependent and mitochondria-independent mechanisms under normoxic and hypoxic conditions.Q51653643
Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosisQ64378116
Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivoQ82518783
MicroRNAs: new players in cardiac injury and protectionQ24635236
MicroRNAs miR-1, miR-133a, miR-133b and miR-208 are dysregulated in human myocardial infarctionQ28268501
Prevention of doxorubicin cardiac toxicity in the mouse by N-acetylcysteineQ28366936
Mechanical stretch via transforming growth factor-β1 activates microRNA208a to regulate endoglin expression in cultured rat cardiac myoblastsQ28568593
Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte deathQ28579471
A family of microRNAs encoded by myosin genes governs myosin expression and muscle performanceQ29619547
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicityQ30500787
Expression of microRNA-208 is associated with adverse clinical outcomes in human dilated cardiomyopathyQ34113952
Mechanism of anthracycline-mediated down-regulation of GATA4 in the heartQ34682797
Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1.Q35868154
Therapeutic inhibition of miR-208a improves cardiac function and survival during heart failureQ35964249
Acetaminophen attenuates doxorubicin-induced cardiac fibrosis via osteopontin and GATA4 regulation: reduction of oxidant levelsQ37086060
The emerging role of microRNAs in cardiac remodeling and heart failureQ37319218
MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice.Q37328435
Distinct mechanisms of cardiomyocyte apoptosis induced by doxorubicin and hypoxia converge on mitochondria and are inhibited by Bcl-xLQ37580188
MicroRNAs: redefining mechanisms in cardiac diseaseQ37833881
Developing microRNA therapeutics: approaching the unique complexities.Q38036732
The emerging role of miR-208a in the heartQ38057365
Requirement for pre-existing of p21 to prevent doxorubicin-induced apoptosis through inhibition of caspase-3 activationQ40243606
Mechanisms of induction of apoptosis by anthraquinone anticancer drugs aclarubicin and mitoxantrone in comparison with doxorubicin: relation to drug cytotoxicity and caspase-3 activationQ40363652
Cooperative interaction between GATA5 and NF-ATc regulates endothelial-endocardial differentiation of cardiogenic cells.Q40712783
Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathwaysQ44822086
Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in miceQ46597560
P275copyright licenseCreative Commons Attribution 3.0 UnportedQ14947546
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectdoxorubicinQ18936
microRNAQ310899
P304page(s)597032
P577publication date2015-06-07
P1433published inOxidative medicine and cellular longevityQ26840015
P1476titleMicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction
P478volume2015

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cites work (P2860)
Q36409311Comment on "MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction"
Q90451191Dexrazoxane Protects Cardiomyocyte from Doxorubicin-Induced Apoptosis by Modulating miR-17-5p
Q48141841Doxorubicin and Liposomal Doxorubicin Differentially Affect Expression of miR-208a and let-7g in Rat Ventricles and Atria.
Q64262548Effects of microRNA-208a on inflammation and oxidative stress in ketamine-induced cardiotoxicity through Notch/NF-κB signal pathways by CHD9
Q58701776Ghrelin Alleviates Angiotensin II-Induced H9c2 Apoptosis: Impact of the miR-208 Family
Q60960509Keeping the Heart Fitm2 during Chemotherapy
Q33733403MicroRNA applications for prostate, ovarian and breast cancer in the era of precision medicine
Q92763592MicroRNA-129-1-3p protects cardiomyocytes from pirarubicin-induced apoptosis by down-regulating the GRIN2D-mediated Ca2+ signalling pathway
Q47204916MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2.
Q90461158MicroRNAs in Cancer Treatment-Induced Cardiotoxicity
Q39304689MicroRNAs in injury and repair
Q58559062Non-coding RNAs: potential regulators in cardio-oncology
Q97643665Noncoding RNAs in doxorubicin-induced cardiotoxicity and their potential as biomarkers and therapeutic targets
Q52663010Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
Q26747609Regulatory mechanisms of microRNA expression
Q27319491RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway
Q47929107Role of microRNAs in doxorubicin-induced cardiotoxicity: an overview of preclinical models and cancer patients.
Q47947947Role of noncoding RNAs in regulation of cardiac cell death and cardiovascular diseases
Q41983421Sarco"MiR" friend or foe: a perspective on the mechanisms of doxorubicin-induced cardiomyopathy
Q61812334miR-499-5p Attenuates Mitochondrial Fission and Cell Apoptosis via p21 in Doxorubicin Cardiotoxicity

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