Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.

scientific article published on 6 March 2018

Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.REDOX.2018.02.026
P932PMC publication ID5953242
P698PubMed publication ID29524841

P2093author name stringLina Xu
Yan Qi
Jinyong Peng
Lianhong Yin
Xufeng Tao
Lisha Zhao
P2860cites workThe role of sirtuins in cardiac diseaseQ27693274
The effect of dexrazoxane on myocardial injury in doxorubicin-treated children with acute lymphoblastic leukemiaQ28271441
Cardiomyocyte autophagy and cancer chemotherapyQ33573823
Cardiotoxicity of doxorubicin and other anthracycline derivativesQ33852542
Total Flavonoids from Clinopodium chinense (Benth.) O. Ktze Protect against Doxorubicin-Induced Cardiotoxicity In Vitro and In VivoQ35136498
MicroRNA-532-3p regulates mitochondrial fission through targeting apoptosis repressor with caspase recruitment domain in doxorubicin cardiotoxicityQ35274471
High Throughput Screening Identifies a Novel Compound Protecting Cardiomyocytes from Doxorubicin-Induced DamageQ35681478
MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac DysfunctionQ35763090
Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathwayQ36361268
Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and ImagingQ36451899
Doxorubicin in experimental and clinical heart failureQ36562427
Oxidative stress and growth-regulating intracellular signaling pathways in cardiac myocytesQ36620605
Anthracycline associated cardiotoxicity in survivors of childhood cancerQ37112428
Dioscin-induced autophagy mitigates cell apoptosis through modulation of PI3K/Akt and ERK and JNK signaling pathways in human lung cancer cell linesQ37300056
Regulation of myocardial growth and death by NADPH oxidaseQ37826870
A new insight into adriamycin-induced cardiotoxicityQ38012571
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Anthracyclines/trastuzumab: new aspects of cardiotoxicity and molecular mechanisms.Q38431346
miRNAs as potential therapeutic targets and diagnostic biomarkers for cardiovascular disease with a particular focus on WO2010091204.Q38669417
Protective effects of dioscin against doxorubicin-induced nephrotoxicity via adjusting FXR-mediated oxidative stress and inflammationQ38721587
miR-140-5p regulates adipocyte differentiation by targeting transforming growth factor-β signalingQ38812460
miR-140-5p inhibits ovarian cancer growth partially by repression of PDGFRA.Q38841797
Pathways of cardiac toxicity: comparison between chemotherapeutic drugs doxorubicin and mitoxantrone.Q38876257
Dioscin alleviates BDL- and DMN-induced hepatic fibrosis via Sirt1/Nrf2-mediated inhibition of p38 MAPK pathwayQ38922785
Dioscin attenuates renal ischemia/reperfusion injury by inhibiting the TLR4/MyD88 signaling pathway via up-regulation of HSP70.Q38966339
Keap1 redox-dependent regulation of doxorubicin-induced oxidative stress response in cardiac myoblastsQ39065082
Dioscin prevents the mitochondrial apoptosis and attenuates oxidative stress in cardiac H9c2 cellsQ39109682
Cancer statistics for African Americans, 2016: Progress and opportunities in reducing racial disparitiesQ39972544
Targeting MicroRNA Function in Acute PancreatitisQ41978704
The antifungal activity and membrane-disruptive action of dioscin extracted from Dioscorea nipponicaQ42713709
Anti-thrombotic activity and chemical characterization of steroidal saponins from Dioscorea zingiberensis C.H. WrightQ42957763
Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats.Q43166156
Emodin Alleviates Sodium Taurocholate-Induced Pancreatic Acinar Cell Injury via MicroRNA-30a-5p-Mediated Inhibition of High-Temperature Requirement A/Transforming Growth Factor Beta 1 Inflammatory SignalingQ43795438
Preventive effects of ellagic acid against doxorubicin-induced cardio-toxicity in miceQ45853133
Diallyl trisulfide suppresses doxorubicin-induced cardiomyocyte apoptosis by inhibiting MAPK/NF-κB signaling through attenuation of ROS generationQ46271795
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2.Q47204916
CTRP3 protected against doxorubicin-induced cardiac dysfunction, inflammation and cell death via activation of Sirt1.Q47603462
Propofol alleviates liver oxidative stress via activating Nrf2 pathwayQ47718195
Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammationQ47805474
Regulation of ADAM10 by miR-140-5p and potential relevance for Alzheimer's diseaseQ47908768
Protective effects of dioscin against cisplatin-induced nephrotoxicity via the microRNA-34a/sirtuin 1 signalling pathway.Q48131275
Dioscin ameliorates cerebral ischemia/reperfusion injury through the downregulation of TLR4 signaling via HMGB-1 inhibitionQ48280594
Protective effect of dioscin against thioacetamide-induced acute liver injury via FXR/AMPK signaling pathway in vivo.Q52840605
Quantitative chemical proteomics for investigating the biomarkers of dioscin against liver fibrosis caused by CCl4 in rats.Q53469990
Doxorubicin-induced cardiomyopathyQ77323607
The role of COX-2 and Nrf2/ARE in anti-inflammation and antioxidative stress: Aging and anti-agingQ84001359
Circulating microRNAs as Biomarkers in Cardiovascular DiseasesQ86809686
P921main subjectmicroRNAQ310899
P304page(s)189-198
P577publication date2018-03-06
P1433published inRedox BiologyQ27724751
P1476titleProtective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress.
P478volume16

Reverse relations

cites work (P2860)
Q60937783Dioscin Inhibits Virulence Factors of
Q64930303Downregulation of miR-130a, antagonized doxorubicin-induced cardiotoxicity via increasing the PPARγ expression in mESCs-derived cardiac cells.
Q59127640Natural Product Interventions for Chemotherapy and Radiotherapy-Induced Side Effects
Q64100444Neuroprotective Effect of Dioscin on the Aging Brain
Q90400038Protective Effects of Dioscin Against Doxorubicin-Induced Hepatotoxicity Via Regulation of Sirt1/FOXO1/NF-κb Signal
Q90070027Recent Advances in the Pharmacological Activities of Dioscin
Q90469804Targeting Reactive Oxygen Species in Cancer via Chinese Herbal Medicine
Q90421154The Effects of Inhibition of MicroRNA-375 in a Mouse Model of Doxorubicin-Induced Cardiac Toxicity
Q59327156The Role of Natural Products in Targeting Cardiovascular Diseases via Nrf2 Pathway: Novel Molecular Mechanisms and Therapeutic Approaches
Q59795304miR-125a-5p ameliorates hepatic glycolipid metabolism disorder in type 2 diabetes mellitus through targeting of STAT3
Q90448502miR-140-5p mediates bevacizumab-induced cytotoxicity to cardiomyocytes by targeting the VEGFA/14-3-3γ signal pathway

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