Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart

scientific article published on November 16, 2010

Mechanism of anthracycline-mediated down-regulation of GATA4 in the heart is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/CVR/CVQ361
P953full work available at URLhttps://academic.oup.com/cardiovascres/article-pdf/90/1/97/17235570/cvq361.pdf
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21084315/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21084315/pdf/?tool=EBI
https://europepmc.org/articles/PMC3058732
https://europepmc.org/articles/PMC3058732?pdf=render
https://doi.org/10.1093/cvr/cvq361
http://academic.oup.com/cardiovascres/article-pdf/90/1/97/17235570/cvq361.pdf
P932PMC publication ID3058732
P698PubMed publication ID21084315
P5875ResearchGate publication ID47811645

P2093author name stringChi-Ming Wong
Lingling Liu
Ah-Mee Park
Hiroko Nagase
Nava Szwergold
Shilpashree Vinod Kumar
Yuichiro J. Suzuki
P2860cites workCardiac-Specific Deletion of Gata4 Reveals Its Requirement for Hypertrophy, Compensation, and Myocyte ViabilityQ57396510
Anthracycline-induced suppression of GATA-4 transcription factor: implication in the regulation of cardiac myocyte apoptosisQ64378116
Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosisQ73678982
Suppression by metallothionein of doxorubicin-induced cardiomyocyte apoptosis through inhibition of p38 mitogen-activated protein kinasesQ73731379
p53 and its homologues, p63 and p73, induce a replicative senescence through inactivation of NF-Y transcription factorQ74604690
Doxorubicin-induced cardiomyopathyQ77323607
Hepatocyte growth factor induces GATA-4 phosphorylation and cell survival in cardiac muscle cellsQ78618797
The B subunit of the CCAAT box binding transcription factor complex (CBF/NF-Y) is essential for early mouse development and cell proliferationQ79370192
Protein carbonylation as a novel mechanism in redox signalingQ80198021
Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivoQ82518783
The molecular biology of the CCAAT-binding factor NF-YQ28138416
Inhibition of Crm1-p53 interaction and nuclear export of p53 by poly(ADP-ribosyl)ationQ28250296
Endothelin-1 induces phosphorylation of GATA-4 transcription factor in the HL-1 atrial-muscle cell lineQ28360896
HL-1 cells: a cardiac muscle cell line that contracts and retains phenotypic characteristics of the adult cardiomyocyteQ29620367
Essential role of GATA-4 in cell survival and drug-induced cardiotoxicityQ30500787
Pulmonary Hypertension-Induced GATA4 Activation in the Right VentricleQ34147487
Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failureQ35131260
Regulation of cardiac myocyte apoptosis by the GATA-4 transcription factorQ35648329
Mitochondrial and nuclear p53 localization in cardiomyocytes: redox modulation by doxorubicin (Adriamycin)?Q36824985
Effects of intermittent hypoxia on the heartQ36825899
The C/EBP family of transcription factors: a paradigm for interaction between gene expression and proliferation controlQ36893970
DNA damage is an early event in doxorubicin-induced cardiac myocyte deathQ40299796
GATA-4 gene organization and analysis of its promoterQ40310267
A chemical inhibitor of p53 that protects mice from the side effects of cancer therapyQ40929887
Glycoprotein 130 regulates cardiac myocyte survival in doxorubicin-induced apoptosis through phosphatidylinositol 3-kinase/Akt phosphorylation and Bcl-xL/caspase-3 interactionQ42498438
Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in miceQ46597560
Effects of intermittent hypoxia on oxidative stress-induced myocardial damage in miceQ48478581
Acute intermittent hypoxia activates myocardial cell survival signaling.Q53584945
p53-induced inhibition of Hif-1 causes cardiac dysfunction during pressure overloadQ57396501
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)97-104
P577publication date2010-11-16
P1433published inCardiovascular ResearchQ4642329
P1476titleMechanism of anthracycline-mediated down-regulation of GATA4 in the heart
P478volume90

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cites work (P2860)
Q94037434Apoptosis-based therapy to treat pulmonary arterial hypertension
Q39264180Autophagy and mitophagy in the context of doxorubicin-induced cardiotoxicity.
Q36957758Cardiac side effects of anticancer treatments: new mechanistic insights
Q42718368Cell signaling pathways for the regulation of GATA4 transcription factor: Implications for cell growth and apoptosis
Q90415843GATA4-targeted compound exhibits cardioprotective actions against doxorubicin-induced toxicity in vitro and in vivo: establishment of a chronic cardiotoxicity model using human iPSC-derived cardiomyocytes
Q60960509Keeping the Heart Fitm2 during Chemotherapy
Q38473474Mechanisms and management of doxorubicin cardiotoxicity
Q35763090MicroRNA-208a Silencing Attenuates Doxorubicin Induced Myocyte Apoptosis and Cardiac Dysfunction
Q36702431Modulators of right ventricular apoptosis and contractility in a rat model of pulmonary hypertension
Q37952284NF-Y and the transcriptional activation of CCAAT promoters.
Q90025681Overexpression of p53 due to excess protein O-GlcNAcylation is associated with coronary microvascular disease in type 2 diabetes
Q30341525Phylogenetic origin of LI-cadherin revealed by protein and gene structure analysis.
Q39268019Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathways
Q26823592The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure

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