Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast.

scientific article

Synergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast. is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode2010PNAS..107.3540T
P356DOI10.1073/PNAS.0911055107
P932PMC publication ID2840417
P698PubMed publication ID20133687
P5875ResearchGate publication ID41408539

P50authorKoji NagaoQ42270085
Tomáš PluskalQ43370334
Alejandro Villar-BrionesQ47474769
P2093author name stringMitsuhiro Yanagida
Takahiro Nakamura
Tomoko Yoshida
Kojiro Takeda
Aya Kokubu
Sakura Kikuchi
P2860cites workFamilial Parkinson disease gene product, parkin, is a ubiquitin-protein ligaseQ22254584
Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolismQ24298601
Parkin is recruited selectively to impaired mitochondria and promotes their autophagyQ24317471
Kinetic analysis of regulatory events in G1 leading to proliferation or quiescence of Swiss 3T3 cellsQ24612401
The cyclosome, a large complex containing cyclin-selective ubiquitin ligase activity, targets cyclins for destruction at the end of mitosisQ24656114
Formation process of autophagosome is traced with Apg8/Aut7p in yeastQ24670615
TOR signaling in growth and metabolismQ27860757
The ubiquitin systemQ27860803
Multiple associated proteins regulate proteasome structure and functionQ27931244
Ump1p is required for proper maturation of the 20S proteasome and becomes its substrate upon completion of the assembly.Q27931305
Role of mitochondria in the pheromone- and amiodarone-induced programmed death of yeastQ27931442
Identification of subunits of the anaphase-promoting complex of Saccharomyces cerevisiaeQ27932699
Proteasome- and SCF-dependent degradation of yeast adenine deaminase upon transition from proliferation to quiescence requires a new F-box protein named Saf1p.Q27934564
Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagyQ27936161
Atg32 is a mitochondrial protein that confers selectivity during mitophagyQ27936726
Regulation of nuclear proteasome by Rhp6/Ubc2 through ubiquitination and destruction of the sensor and anchor Cut8.Q27936888
Reversible cytoplasmic localization of the proteasome in quiescent yeast cells.Q27940379
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
CRM1 is responsible for intracellular transport mediated by the nuclear export signalQ29547861
Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per proteinQ29617305
Intracellular antioxidants: from chemical to biochemical mechanismsQ33763063
Fission yeast Cut2 required for anaphase has two destruction boxes.Q33887593
"Sleeping beauty": quiescence in Saccharomyces cerevisiaeQ34348944
A conditional lethal mutant in the fission yeast 26 S protease subunit mts3+ is defective in metaphase to anaphase transitionQ36797998
Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeastQ38262583
Two-step, extensive alterations in the transcriptome from G0 arrest to cell division in Schizosaccharomyces pombeQ38516125
Expression of hsp16 in response to nucleotide depletion is regulated via the spc1 MAPK pathway in Schizosaccharomyces pombeQ39095949
Global transcriptional responses of fission yeast to environmental stressQ39697098
Environmental toxicants inhibit neuronal Jak tyrosine kinase by mitochondrial disruptionQ39820257
The role of proteolysis in cell cycle progression in Schizosaccharomyces pombeQ41077453
Localization of the 26S proteasome during mitosis and meiosis in fission yeastQ42660117
Metabolic profiling of the fission yeast S. pombe: quantification of compounds under different temperatures and genetic perturbation.Q43213972
Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic response to Bortezomib, a novel proteasome inhibitor, in human H460 non-small cell lung cancer cellsQ44488098
Genetic control of cellular quiescence in S. pombeQ46051233
Persistent mitochondrial dysfunction and oxidative stress hinder neuronal cell recovery from reversible proteasome inhibitionQ46733610
Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunitsQ46853059
20S cyclosome complex formation and proteolytic activity inhibited by the cAMP/PKA pathwayQ48057777
Proteasome inhibitors induce cytochrome c-caspase-3-like protease-mediated apoptosis in cultured cortical neurons.Q52537613
Fission yeast autophagy induced by nitrogen starvation generates a nitrogen source that drives adaptation processes.Q53726785
A nitrogen starvation-induced dormant G0 state in fission yeast: the establishment from uncommitted G1 state and its delay for return to proliferationQ71517207
Cut8, essential for anaphase, controls localization of 26S proteasome, facilitating destruction of cyclin and Cut2Q73205111
Schizosaccharomyces pombe cells deficient in triacylglycerols synthesis undergo apoptosis upon entry into the stationary phaseQ73918457
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectautophagyQ288322
lifetimeQ22675021
P304page(s)3540-3545
P577publication date2010-02-04
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleSynergistic roles of the proteasome and autophagy for mitochondrial maintenance and chronological lifespan in fission yeast
P478volume107

Reverse relations

cites work (P2860)
Q27933297A stress-responsive system for mitochondrial protein degradation
Q33807670Adaptive Roles of SSY1 and SIR3 During Cycles of Growth and Starvation in Saccharomyces cerevisiae Populations Enriched for Quiescent or Nonquiescent Cells
Q26866874Aging and cell death in the other yeasts, Schizosaccharomyces pombe and Candida albicans
Q48259158Atg20- and Atg24-family proteins promote organelle autophagy in fission yeast
Q101162457Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast
Q37057311Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast.
Q36523600Decoupling nutrient signaling from growth rate causes aerobic glycolysis and deregulation of cell size and gene expression
Q85635197Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome
Q36811863Dihydroartemisinin induces autophagy and inhibits the growth of iron-loaded human myeloid leukemia K562 cells via ROS toxicity
Q34148364Effects of calorie restriction on life span of microorganisms
Q34023025Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae
Q38188810From cradle to grave: high-throughput studies of aging in model organisms
Q37461833Genes for plant autophagy: functions and interactions
Q21132034Genetic and metabolomic dissection of the ergothioneine and selenoneine biosynthetic pathway in the fission yeast, S. pombe, and construction of an overproduction system
Q38103239Genome-scale studies of aging: challenges and opportunities
Q103824051High-Throughput Flow Cytometry Combined with Genetic Analysis Brings New Insights into the Understanding of Chromatin Regulation of Cellular Quiescence
Q28478963Identification of genes affecting the toxicity of anti-cancer drug bortezomib by genome-wide screening in S. pombe
Q90078103Identification of ubiquitin-proteasome system components affecting the degradation of the transcription factor Pap1
Q42142886Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA.
Q35345545Implications for proteasome nuclear localization revealed by the structure of the nuclear proteasome tether protein Cut8.
Q27937757Integrity of the Saccharomyces cerevisiae Rpn11 protein is critical for formation of proteasome storage granules (PSG) and survival in stationary phase
Q47647351Mechanisms and Physiological Roles of Mitophagy in Yeast.
Q31147786Metabolomic Analysis of Schizosaccharomyces pombe: Sample Preparation, Detection, and Data Interpretation
Q33662943Microtubule-dependent spatial organization of mitochondria in fission yeast
Q37918611Mitochondria and autophagy: critical interplay between the two homeostats
Q26995343Mitochondria and the autophagy-inflammation-cell death axis in organismal aging
Q60621177Mitochondria in Cardiac Disease
Q58905388Mitochondrial Regulation by PINK1-Parkin Signaling
Q27001551Mitochondrial dynamics and mitophagy in Parkinson's disease: disordered cellular power plant becomes a big deal in a major movement disorder
Q37819319Mitochondrial turnover in the heart
Q92857669Mitophagy in Yeast
Q38325180Mitophagy in yeast: Molecular mechanisms and physiological role
Q34787497Nuclear protein quality is regulated by the ubiquitin-proteasome system through the activity of Ubc4 and San1 in fission yeast
Q34923804Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.
Q42235376Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane
Q38286869Protecting the mitochondrial powerhouse.
Q36234472Quiescent fibroblasts are protected from proteasome inhibition-mediated toxicity
Q51396383RNA interference is essential for cellular quiescence.
Q26821921Receptor-mediated mitophagy in yeast and mammalian systems
Q37840159Redox control of the ubiquitin-proteasome system: from molecular mechanisms to functional significance.
Q39427702Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome
Q37672114Regulation of autophagy and mitophagy by nutrient availability and acetylation
Q27930881Spg5 protein regulates the proteasome in quiescence
Q27077073Starvation induced cell death in autophagy-defective yeast mutants is caused by mitochondria dysfunction
Q33980608Synchronized fission yeast meiosis using an ATP analog-sensitive Pat1 protein kinase.
Q53059018The 19S proteasome subunit Rpt3 regulates distribution of CENP-A by associating with centromeric chromatin.
Q91717563The Role and Mechanism of SIRT1 in Resveratrol-regulated Osteoblast Autophagy in Osteoporosis Rats
Q90747892The fission yeast Greatwall-Endosulfine pathway is required for proper quiescence/G0 phase entry and maintenance
Q53643796The impact of medium acidity on the chronological life span of Saccharomyces cerevisiae - lipids, signaling cascades, mitochondrial and vacuolar functions.
Q90722110The putative ceramide-conjugation protein Cwh43 regulates G0 quiescence, nutrient metabolism and lipid homeostasis in fission yeast
Q39755736The role of frataxin in fission yeast iron metabolism: implications for Friedreich's ataxia
Q50466319Unexpected similarities between the Schizosaccharomyces and human blood metabolomes, and novel human metabolites.
Q34370238Upregulation of the mitochondrial Lon Protease allows adaptation to acute oxidative stress but dysregulation is associated with chronic stress, disease, and aging.
Q37693585Walking the oxidative stress tightrope: a perspective from the naked mole-rat, the longest-living rodent
Q54240769bZIP transcription factor SmJLB1 regulates autophagy-related genes Smatg8 and Smatg4 and is required for fruiting-body development and vegetative growth in Sordaria macrospora.