Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy

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Trichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy is …
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scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2017.00636
P932PMC publication ID5449505
P698PubMed publication ID28620388

P2093author name stringJingjing Huang
Yi Chen
Bin Zhan
Shuai Shao
Limei Zhao
Ximeng Sun
Ran Sun
Xinping Zhu
P2860cites workThe C3b/C4b receptor is recognized by the Knops, McCoy, Swain-langley, and York blood group antiseraQ24675861
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Macrophage polarization in health and diseaseQ27027054
Human Astrovirus Coat Protein Inhibits Serum Complement Activation via C1, the First Component of the Classical PathwayQ27485323
Establishment and characterization of a human acute monocytic leukemia cell line (THP-1)Q28276146
Pseudomonas aeruginosa alkaline protease blocks complement activation via the classical and lectin pathwaysQ28493231
Borrelia burgdorferi BBK32 Inhibits the Classical Pathway by Blocking Activation of the C1 Complement ComplexQ28552790
Macrophages migrate in an activation-dependent manner to chemokines involved in neuroinflammationQ30573013
A calreticulin-like molecule from the human hookworm Necator americanus interacts with C1q and the cytoplasmic signalling domains of some integrins.Q32156259
Fasciola hepatica cathepsin L suppresses sheep lymphocyte proliferation in vitro and modulates surface CD4 expression on human and ovine T cellsQ43902970
The classical activation pathway of the human complement system is specifically inhibited by calreticulin from Trypanosoma cruziQ44772790
Scabies mite inactivated serine protease paralogs inhibit the human complement system.Q45983857
Interaction of human C1q with IgG and IgM: revisitedQ46249194
Staining of the Ca2+-binding proteins, calsequestrin, calmodulin, troponin C, and S-100, with the cationic carbocyanine dye “Stains-all”Q50927230
Interaction between pancreatic cancer cells and tumor-associated macrophages promotes the invasion of pancreatic cancer cells and the differentiation and migration of macrophages.Q53646506
Trypanosoma carassii calreticulin binds host complement component C1q and inhibits classical complement pathway-mediated lysisQ58844127
Excretory–secretory proteome of larval Schistosoma mansoni and Echinostoma caproni, two parasites of Biomphalaria glabrataQ61780865
Human C1q induces eosinophil migrationQ71535862
Dynamics of the IgG3 responses following immunisation of BALB/c mice with somatic and excretory/secretory antigens from various Trichinella speciesQ73264115
The role of the macrophage in immune regulationQ77675946
Macrophage killing of Leishmania amazonensis amastigotes requires both nitric oxide and superoxideQ80140621
Trichinella spiralis: macrophage activity and antibody response in chronic murine infectionQ81452883
Calreticulin from the intestinal nematode Heligmosomoides polygyrus is a Th2-skewing protein and interacts with murine scavenger receptor-AQ83087542
Excretory/secretory products from Trichinella spiralis adult worms ameliorate DSS-induced colitis in miceQ33560624
Complement evasion by human pathogensQ33623972
C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells.Q33745559
Calreticulin: one protein, one gene, many functions.Q33776572
Monocyte Expressed Macromolecular C1 and C1q Receptors as Molecular Sensors of Danger: Implications in SLEQ33808073
International Commission on Trichinellosis: recommendations on methods for the control of Trichinella in domestic and wild animals intended for human consumptionQ33926813
Trichinella spiralis paramyosin binds to C8 and C9 and protects the tissue-dwelling nematode from being attacked by host complementQ33959409
Nippocystatin, a cysteine protease inhibitor from Nippostrongylus brasiliensis, inhibits antigen processing and modulates antigen-specific immune responseQ34009625
Trichinellosis: a worldwide zoonosisQ34094728
Vaccination of mice against intestinal Trichinella spiralis infections by oral administration of antigens microencapsulated in methacrilic acid copolymers.Q34489531
Immunoproteomic profile of Trichinella spiralis adult worm proteins recognized by early infection seraQ34985870
Cytokine, antibody and proliferative cellular responses elicited by Taenia solium calreticulin upon experimental infection in hamstersQ35220023
In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q.Q35237370
Partially Protective Immunity Induced by a 20 kDa Protein Secreted by Trichinella spiralis StichocytesQ35750466
Role of calreticulin from parasites in its interaction with vertebrate hostsQ35764951
Trichinella spiralis Paramyosin Binds Human Complement C1q and Inhibits Classical Complement ActivationQ35882694
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.Q35981460
Complement: central to innate immunity and bridging to adaptive responses.Q36064092
Microbial metabolite butyrate facilitates M2 macrophage polarization and functionQ36814971
World distribution of Trichinella spp. infections in animals and humansQ36906109
Macrophage-mediated inflammatory response decreases mycobacterial survival in mouse MSCs by augmenting NO productionQ36959378
Biology and genome of Trichinella spiralisQ37020540
Human and mouse macrophages collaborate with neutrophils to kill larval Strongyloides stercoralisQ37123835
The non-classical functions of the classical complement pathway recognition subcomponent C1q.Q37728390
Complement and non-complement activating functions of C1q: a prototypical innate immune moleculeQ37859539
THP-1 cell line: an in vitro cell model for immune modulation approachQ38240595
Complement, c1q, and c1q-related molecules regulate macrophage polarizationQ38246272
Characterization of Haemonchus contortus calreticulin suggests its role in feeding and immune evasion by the parasiteQ38330539
T-cell clones in human trichinellosis: Evidence for a mixed Th1/Th2 response.Q38969424
Binding of Streptococcus pneumoniae endopeptidase O (PepO) to complement component C1q modulates the complement attack and promotes host cell adherence.Q39003448
Direct interaction between CD91 and C1q.Q39666596
Influenza A virus M1 blocks the classical complement pathway through interacting with C1qA.Q39816387
Role of complement component C1q in phagocytosis of Listeria monocytogenes by murine macrophage-like cell lines.Q40268528
The contribution of both oxygen and nitrogen intermediates to the intracellular killing mechanisms of C1q-opsonized Listeria monocytogenes by the macrophage-like IC-21 cell line.Q40851945
The human monocyte-like cell line THP-1 expresses Fc gamma RI and Fc gamma RII.Q41682581
Oral vaccination with Ts87 DNA vaccine delivered by attenuated Salmonella typhimurium elicits a protective immune response against Trichinella spiralis larval challengeQ43544515
P921main subjectTrichinella spiralisQ730937
evasion of host immune responseQ1660157
P304page(s)636
P577publication date2017-05-31
P1433published inFrontiers in ImmunologyQ27723748
P1476titleTrichinella spiralis Calreticulin Binds Human Complement C1q As an Immune Evasion Strategy
P478volume8

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cites work (P2860)
Q94596514A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice
Q92661862Comparative Proteomic Analysis of Serum from Pigs Experimentally Infected with Trichinella spiralis, Trichinella britovi, and Trichinella pseudospiralis
Q64069996Complement Evasion: An Effective Strategy That Parasites Utilize to Survive in the Host
Q60932060Mapping of the complement C1q binding site on Trichinella spiralis paramyosin
Q98778763Probiotic Bacteria can Modulate Murine Macrophage's Superoxide Production in Trichinella Spiralis Infection
Q55374627Proteomic analysis of the response of Trichinella spiralis muscle larvae to exogenous nitric oxide.
Q98465708The Interactions of Parasite Calreticulin With Initial Complement Components: Consequences in Immunity and Virulence
Q59136226Trichinella britovi muscle larvae and adult worms: stage-specific and common antigens detected by two-dimensional gel electrophoresis-based immunoblotting
Q99577395Trichinella spiralis: inflammation modulator

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