scholarly article | Q13442814 |
P50 | author | Elizabeth V Clarke | Q59684151 |
P2093 | author name string | Andrea J Tenner | |
Deborah A Fraser | |||
Pedro Morgado | |||
Marie E Benoit | |||
P2860 | cites work | The PAAD/PYRIN-only protein POP1/ASC2 is a modulator of ASC-mediated nuclear-factor-kappa B and pro-caspase-1 regulation | Q24298443 |
IL-33 amplifies the polarization of alternatively activated macrophages that contribute to airway inflammation | Q24309034 | ||
Complement classical pathway components are all important in clearance of apoptotic and secondary necrotic cells | Q24322831 | ||
The CATERPILLER protein monarch-1 is an antagonist of toll-like receptor-, tumor necrosis factor alpha-, and Mycobacterium tuberculosis-induced pro-inflammatory signals | Q24337585 | ||
Interleukin-10: new perspectives on an old cytokine | Q24653771 | ||
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cells | Q24670661 | ||
Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation | Q57258441 | ||
Characterization of C1q receptor expression on human phagocytic cells: effects of PDBu and fMLP | Q68798810 | ||
Purification and radiolabeling of human C1q | Q70831006 | ||
Expression of C1q, a subcomponent of the rat complement system, is dramatically enhanced in brains of rats with either Borna disease or experimental allergic encephalomyelitis | Q71707145 | ||
C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited | Q73326011 | ||
The globular heads of C1q specifically recognize surface blebs of apoptotic vascular endothelial cells | Q73509925 | ||
Complement receptor type 1 (CR1, CD35) is a receptor for C1q | Q73767610 | ||
Maturation of dendritic cells abrogates C1q production in vivo and in vitro | Q75272880 | ||
Opsonization with C1q and mannose-binding lectin targets apoptotic cells to dendritic cells | Q80475635 | ||
Minimum information about a microarray experiment (MIAME)-toward standards for microarray data | Q27860569 | ||
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
Analyzing real-time PCR data by the comparative C(T) method | Q28131831 | ||
IL-37 is a fundamental inhibitor of innate immunity | Q28295265 | ||
COPs and POPs: modulators of inflammasome activity | Q28387485 | ||
Integration of biological networks and gene expression data using Cytoscape | Q28681323 | ||
Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm | Q29614349 | ||
How dying cells alert the immune system to danger | Q29615501 | ||
TM4 microarray software suite | Q29618829 | ||
Gene expression of the A- and B-chain of mouse C1q in different tissues and the characterization of the recombinant A-chain | Q33436583 | ||
C1q enhances microglial clearance of apoptotic neurons and neuronal blebs, and modulates subsequent inflammatory cytokine production | Q33601747 | ||
The complement cascade: Yin-Yang in neuroinflammation--neuro-protection and -degeneration | Q33685823 | ||
C1q differentially modulates phagocytosis and cytokine responses during ingestion of apoptotic cells by human monocytes, macrophages, and dendritic cells. | Q33745559 | ||
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo | Q33912964 | ||
Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages | Q33919041 | ||
Systemic lupus erythematosus, complement deficiency, and apoptosis | Q34082803 | ||
The inflammatory response to cell death | Q34718276 | ||
C1q deficiency leads to the defective suppression of IFN-alpha in response to nucleoprotein containing immune complexes | Q34729450 | ||
The role of complement in the development of systemic lupus erythematosus | Q35698485 | ||
Complement proteins C1q and MBL are pattern recognition molecules that signal immediate and long-term protective immune functions | Q36565247 | ||
The complement protein properdin binds apoptotic T cells and promotes complement activation and phagocytosis. | Q36752476 | ||
Clearance of apoptotic cells by phagocytes | Q36850155 | ||
Complement activation and inhibition: a delicate balance. | Q37368654 | ||
Systemic lupus erythematosus and C1q: A quantitative ELISA for determining C1q levels in serum | Q39327756 | ||
Direct demonstration and quantitation of the first complement component in human serum | Q39477585 | ||
Role of surfactant proteins A, D, and C1q in the clearance of apoptotic cells in vivo and in vitro: calreticulin and CD91 as a common collectin receptor complex | Q39750562 | ||
Acquisition of chemiluminescent signals from immunoblots with a digital single-lens reflex camera | Q39902264 | ||
Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation | Q39980543 | ||
Complement subcomponent C1q stimulates Ig production by human B lymphocytes | Q41683610 | ||
Biosynthesis in vitro of complement subcomponents C1q, C1s and C1̅ inhibitor by resting and stimulated human monocytes | Q41843990 | ||
Complement subcomponent C1q secreted by cultured human monocytes has subunit structure identical with that of serum C1q. | Q41940468 | ||
Complement protein C1q-mediated neuroprotection is correlated with regulation of neuronal gene and microRNA expression | Q42719812 | ||
Phagocytic cell molecules that bind the collagen-like region of C1q. Involvement in the C1q-mediated enhancement of phagocytosis | Q43788310 | ||
Janus kinase 3 down-regulates lipopolysaccharide-induced IL-1 beta-converting enzyme activation by autocrine IL-10. | Q44832283 | ||
C1q and MBL, components of the innate immune system, influence monocyte cytokine expression. | Q45973916 | ||
Kainic acid and decorticating lesions stimulate the synthesis of C1q protein in adult rat brain. | Q46138240 | ||
Infiltrating dendritic cells contribute to local synthesis of C1q in murine and human lupus nephritis | Q46189746 | ||
Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis | Q47992020 | ||
Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells. | Q51030802 | ||
The dissociation properties of native C1 | Q52717945 | ||
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies | Q57089602 | ||
P4510 | describes a project that uses | ImageJ | Q1659584 |
Cytoscape | Q3699942 | ||
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | macrophage | Q184204 |
inflammasome complex | Q412405 | ||
apoptotic process | Q14599311 | ||
P304 | page(s) | 5682-5693 | |
P577 | publication date | 2012-04-20 | |
P1433 | published in | Journal of Immunology | Q3521441 |
P1476 | title | Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells | |
P478 | volume | 188 |
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Q52650379 | C1r/C1s deficiency is insufficient to induce murine systemic lupus erythematosus. |
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