Cigarette smoke-induced reduction of C1q promotes emphysema

scientific article published on 21 May 2019

Cigarette smoke-induced reduction of C1q promotes emphysema is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1172/JCI.INSIGHT.124317
P932PMC publication ID6629245
P698PubMed publication ID31112138

P50authorGretchen E. DiehlQ73914593
Matthew C MadisonQ88112062
P2093author name stringDavid B Corry
Farrah Kheradmand
Holger K Eltzschig
Xiaoyi Yuan
Cheng-Yen Chang
Ran You
Roger D Rossen
Cristian Coarfa
Li-Zhen Song
Ming Shan
Sarah Perusich
Lorraine Cornwell
Rick Wetsel
Bon Hee Gu
Rajapakshe Kimal
P2860cites workGene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profilesQ24536351
C1q and mannose binding lectin engagement of cell surface calreticulin and CD91 initiates macropinocytosis and uptake of apoptotic cellsQ24670661
Recent advances in the genetics of autoimmune diseaseQ28238782
Complement: a key system for immune surveillance and homeostasisQ29615484
Activation and regulation of the inflammasomesQ29615664
Complement regulators and inhibitory proteinsQ33386110
Complement C1q activates tumor suppressor WWOX to induce apoptosis in prostate cancer cellsQ33457187
C1q as an autocrine and paracrine regulator of cellular functionsQ39028351
C1q: A fresh look upon an old moleculeQ39364237
Cellular and molecular mechanisms of asthma and COPD.Q39403255
Cell-specific deletion of C1qa identifies microglia as the dominant source of C1q in mouse brainQ40306336
Autoimmunity and atherosclerosis: the presence of antinuclear antibodies is associated with decreased carotid elasticity in young women. The Cardiovascular Risk in Young Finns StudyQ43271779
C1q arrests the cell cycle progression of fibroblasts in G(1) phase: role of the cAMP/PKA-I pathwayQ43546871
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune responseQ45292627
Circulating desmosine levels do not predict emphysema progression but are associated with cardiovascular risk and mortality in COPD.Q47874561
Lung myeloid dendritic cells coordinately induce TH1 and TH17 responses in human emphysema.Q50557641
Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells.Q51030802
Complement and the Regulation of T Cell Responses.Q52574294
CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice.Q53548568
COPD in 2016: some answers, more questions.Q55131706
SLE with C1q deficiency treated with fresh frozen plasma: a 10-year experienceQ57089437
Relative Contribution of C1q and Apoptotic Cell-Surface Calreticulin to Macrophage PhagocytosisQ58212954
Anti-tissue antibodies are related to lung function in chronic obstructive pulmonary diseaseQ58840453
Hypocomplementemic urticarial vasculitis syndrome. Clinical and serologic findings in 18 patientsQ72477525
In vitro generation of CD4+ CD25+ regulatory cells from murine naive T cellsQ80643410
The regulatory dendritic cell marker C1q is a potent inhibitor of allergic inflammationQ88535342
The Challenge of Controlling the COPD Epidemic: Unmet NeedsQ88736631
Extracellular adenosine-mediated modulation of regulatory T cellsQ33878542
Antielastin autoimmunity in tobacco smoking-induced emphysemaQ34621456
Complement regulation of T-cell alloimmunity.Q35151737
Complement protein C1q bound to apoptotic cells suppresses human macrophage and dendritic cell-mediated Th17 and Th1 T cell subset proliferation.Q35227723
Ongoing airway inflammation in patients with COPD who do not currently smokeQ35533404
Activation of C3a receptor is required in cigarette smoke-mediated emphysemaQ35680500
Risk factors for rheumatoid arthritisQ35821581
Complement protein C1q directs macrophage polarization and limits inflammasome activity during the uptake of apoptotic cells.Q35981460
Loss of epigenetic modification driven by the Foxp3 transcription factor leads to regulatory T cell insufficiencyQ35992006
The development and immunosuppressive functions of CD4(+) CD25(+) FoxP3(+) regulatory T cells are under influence of the adenosine-A2A adenosine receptor pathway.Q36075960
The microRNA miR-22 inhibits the histone deacetylase HDAC4 to promote T(H)17 cell-dependent emphysemaQ36134550
Nanoparticulate carbon black in cigarette smoke induces DNA cleavage and Th17-mediated emphysemaQ36182550
Relation between duration of smoking cessation and bronchial inflammation in COPDQ36183908
Autoreactive T Cells in Human Smokers is Predictive of Clinical OutcomeQ36190792
C1q limits dendritic cell differentiation and activation by engaging LAIR-1Q36414882
Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD)Q36516546
Fundamental role of C1q in autoimmunity and inflammationQ36972852
The scavenger receptor SCARF1 mediates the clearance of apoptotic cells and prevents autoimmunityQ37119247
Complement in human diseases: Lessons from complement deficienciesQ37501005
Human C1q Induces Apoptosis in an Ovarian Cancer Cell Line via Tumor Necrosis Factor PathwayQ37521362
COPD is associated with production of autoantibodies to a broad spectrum of self-antigens, correlative with disease phenotype.Q37572312
Agonistic induction of PPARγ reverses cigarette smoke-induced emphysemaQ37602184
Cigarette smoke induction of osteopontin (SPP1) mediates T(H)17 inflammation in human and experimental emphysemaQ37641609
Effects of tobacco smoke on immunity, inflammation and autoimmunityQ37665006
Prevention of autoimmune rheumatic disease: state of the art and future perspectivesQ37811620
Autoimmunity in chronic obstructive pulmonary disease: clinical and experimental evidenceQ37990551
COPD: definition and phenotypesQ38186284
The complement system in systemic lupus erythematosus: an updateQ38213193
The paradoxical roles of C1q and C3 in autoimmunityQ38498407
The 2017 Update to the COPD Foundation COPD Pocket Consultant GuideQ38604593
The critical role of epigenetics in systemic lupus erythematosus and autoimmunityQ38891326
Production of complement components by cells of the immune system.Q38935414
Complement in removal of the dead - balancing inflammationQ38991044
P921main subjectpulmonary emphysemaQ188605
P577publication date2019-05-21
P1433published inJCI insightQ27727187
P1476titleCigarette smoke-induced reduction of C1q promotes emphysema
P478volume5

Reverse relations

Q90341768Individuals at risk of seropositive rheumatoid arthritis: the evolving storycites workP2860

Search more.