Production of complement components by cells of the immune system.

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Production of complement components by cells of the immune system. is …
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scholarly articleQ13442814

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P356DOI10.1111/CEI.12952
P932PMC publication ID5383442
P698PubMed publication ID28249350

P50authorLeendert A TrouwQ40406948
Mieke van EssenQ63987248
P2093author name stringC van Kooten
R Lubbers
P2860cites workgamma-Interferon increases expression of class III complement genes C2 and factor B in human monocytes and in murine fibroblasts transfected with human C2 and factor B genesQ69873172
Generation of C3a anaphylatoxin from human C3 by human mast cell tryptaseQ70246701
The secretion of the third component of complement (C3) by human polymorphonuclear leucocytes from both normal and systemic lupus erythematosus casesQ70525487
Increased biosynthesis of complement components by cultured monocytes, synovial fluid macrophages and skynovial membrane cells from patients with rheumatoid arthritisQ71885453
Human polymorphonuclear leukocytes store large amounts of terminal complement components C7 and C6, which may be released on stimulationQ72169141
IgA and IgG immune complexes increase human macrophage C3 biosynthesisQ72238539
Complement component C7. Assessment of in vivo synthesis after liver transplantation reveals that hepatocytes do not synthesize the majority of human C7Q72363605
Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophilsQ73287589
Cellular localization of complement C3 and C4 transcripts in intestinal specimens from patients with Crohn's diseaseQ73664136
Maturation of dendritic cells abrogates C1q production in vivo and in vitroQ75272880
Evaluation of C3a receptor expression on human leucocytes by the use of novel monoclonal antibodiesQ78127364
Overexpression of complement receptors and related antigens on the surface of bone marrow mast cells in patients with systemic mastocytosisQ78833492
Dendritic cells in the arterial wall express C1q: potential significance in atherogenesisQ79106760
Complement alternative pathway acts as a positive feedback amplification of neutrophil activationQ82382595
Complement--tapping into new sites and effector systemsQ85959086
Expression and regulation of complement receptors by human natural killer cellsQ87771669
rC5a directs the in vitro migration of human memory and naive tonsillar B lymphocytes: implications for B cell trafficking in secondary lymphoid tissuesQ22009921
Identification of human CD93 as the phagocytic C1q receptor (C1qRp) by expression cloningQ24292115
Human adipsin is identical to complement factor D and is expressed at high levels in adipose tissueQ24292702
Human C1qRp is identical with CD93 and the mNI-11 antigen but does not bind C1qQ24296794
CRIg: a macrophage complement receptor required for phagocytosis of circulating pathogensQ24307492
Effect of interferon-gamma on complement gene expression in different cell typesQ24527334
The human C3a receptor is expressed on neutrophils and monocytes, but not on B or T lymphocytesQ24653022
Systemic Lupus Erythematosus and Deficiencies of Early Components of the Complement Classical PathwayQ26768534
Complement regulation of T cell immunityQ26827470
A crystal structure of the complex between human complement receptor 2 and its ligand C3dQ27667612
Structural insight on the recognition of surface-bound opsonins by the integrin I domain of complement receptor 3Q27680051
C3a and C5a are chemotaxins for human mast cells and act through distinct receptors via a pertussis toxin-sensitive signal transduction pathwayQ28116293
Structure of C3b in complex with CRIg gives insights into regulation of complement activationQ28269302
C3d of complement as a molecular adjuvant: bridging innate and acquired immunityQ28272810
Complement receptors in neutrophilsQ28273972
Biosynthesis of the first component of complement by human and guinea pig peritoneal macrophages: evidence for an independent production of the C1 subunitsQ28276981
Human M-ficolin is a secretory protein that activates the lectin complement pathwayQ28610924
Complement: a key system for immune surveillance and homeostasisQ29615484
Biosynthesis of the third component of complement (C3) in vitro by monocytes from both normal and homozygous C3-deficient humansQ30449886
Complement regulators and inhibitory proteinsQ33386110
Of mice and men: The factor H protein family and complement regulation.Q33421580
Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cellsQ33570304
The role of complement in the acquired immune responseQ33917858
C1q receptors.Q33938158
Regulation of the synthesis of C1 subcomponents and C1-inhibitorQ34340423
Immune cell-derived C3a and C5a costimulate human T cell alloimmunity.Q34370940
Complement System Part I - Molecular Mechanisms of Activation and RegulationQ34481071
Human complement receptors for C3b (CR1) and C3d (CR2).Q34564402
Locally produced complement fragments C5a and C3a provide both costimulatory and survival signals to naive CD4+ T cellsQ34760201
Complement Receptor 1: disease associations and therapeutic implications.Q34878497
Expression of complement components, receptors and regulators by human dendritic cells.Q34885229
Molecular basis for complement recognition by integrin αXβ2.Q35849584
Complement C3dg-mediated erythrophagocytosis: implications for paroxysmal nocturnal hemoglobinuria.Q35953532
C5a stimulates secretion of tumor necrosis factor from human mononuclear cells in vitro. Comparison with secretion of interleukin 1 beta and interleukin 1 alphaQ36355106
Decay-accelerating factor modulates induction of T cell immunityQ36403001
Local release of properdin in the cellular microenvironment: role in pattern recognition and amplification of the alternative pathway of complement.Q36540594
C1q acts in the tumour microenvironment as a cancer-promoting factor independently of complement activationQ36541076
Complement biosynthesis by the human hepatoma-derived cell line HepG2Q36987205
Donor deficiency of decay-accelerating factor accelerates murine T cell-mediated cardiac allograft rejectionQ37106399
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4⁺ T cells.Q37241002
A role of macrophage complement receptor CRIg in immune clearance and inflammation.Q37254633
Complement production and regulation by dendritic cells: molecular switches between tolerance and immunityQ37300233
Intracellular complement activation sustains T cell homeostasis and mediates effector differentiationQ37397572
The non-classical functions of the classical complement pathway recognition subcomponent C1q.Q37728390
The role of complement regulatory proteins in peripheral blood cells of patients with systemic lupus erythematosus: reviewQ38026309
The role of complement in CD4⁺ T cell homeostasis and effector functionsQ38110968
Complement deficiencies in systemic lupus erythematosusQ38210887
Complement, c1q, and c1q-related molecules regulate macrophage polarizationQ38246272
C1q, antibodies and anti-C1q autoantibodies.Q38511260
Complement component C3 - The "Swiss Army Knife" of innate immunity and host defenseQ38558926
A journey through the lectin pathway of complement-MBL and beyondQ38558930
Complement C3 is expressed by mast cells in cutaneous vasculitis and is degraded by chymaseQ38755354
The complement and contact activation systems: partnership in pathogenesis beyond angioedemaQ38991081
High expression of C5L2 correlates with high proinflammatory cytokine expression in advanced human atherosclerotic plaquesQ39193960
The production and secretion of complement component C1q by human mast cellsQ39371149
Levels of lectin pathway proteins in plasma and synovial fluid of rheumatoid arthritis and osteoarthritisQ39764375
Synthesis of complement by macrophages and modulation of their functions through complement activationQ40169178
NETosing Neutrophils Activate Complement Both on Their Own NETs and Bacteria via Alternative and Non-alternative PathwaysQ40171437
Factor H uptake regulates intracellular C3 activation during apoptosis and decreases the inflammatory potential of nucleosomes.Q40187096
Structure, function and cellular expression of complement anaphylatoxin receptorsQ40540064
Mucosal type mast cells express complement receptor type 2 (CD21).Q40732437
Molecular assembly of CD46 with CD9, alpha3-beta1 integrin and protein tyrosine phosphatase SHP-1 in human macrophages through differentiation by GM-CSF.Q40749141
Properdin: approaching four decades of researchQ40804724
Cutting edge: CD46, a new costimulatory molecule for T cells, that induces p120CBL and LAT phosphorylationQ40875377
CR3 (CD11b, CD18): a phagocyte and NK cell membrane receptor with multiple ligand specificities and functionsQ40903321
The receptor for complement anaphylatoxin C3a is expressed by myeloid cells and nonmyeloid cells in inflamed human central nervous system: analysis in multiple sclerosis and bacterial meningitis.Q41052853
Biosynthesis and secretion of complement component (C3) by activated human polymorphonuclear leukocytesQ41108317
Complement receptor type 1 (CR1/CD35) expressed on activated human CD4+ T cells contributes to generation of regulatory T cellsQ41288623
Differential expression of complement receptors on human basophils and mast cells. Evidence for mast cell heterogeneity and CD88/C5aR expression on skin mast cells.Q41294733
Extrahepatic complement biosynthesis: where, when and why?Q41331539
Modified low density lipoprotein stimulates complement C3 expression and secretion via liver X receptor and Toll-like receptor 4 activation in human macrophages.Q41482082
Expression of properdin in human monocytesQ41491340
Properdin, a positive regulator of complement activation, is expressed in human T cell lines and peripheral blood T cellsQ41529943
Complement factors H and I synthesized by B cell lines function to generate a growth factor activity from C3.Q41555822
Detection of properdin mRNA in human peripheral blood monocytes and spleenQ41595530
Synthesis of complement component C5 by human B and T lymphoblastoid cell linesQ41756353
Biosynthesis in vitro of complement subcomponents C1q, C1s and C1̅ inhibitor by resting and stimulated human monocytesQ41843990
Biosynthesis of the complement components and the regulatory proteins of the alternative complement pathway by human peripheral blood monocytesQ41894352
Complement-subcomponent-C1-inhibitor synthesis by human monocytesQ41917355
Complement subcomponent C1q secreted by cultured human monocytes has subunit structure identical with that of serum C1q.Q41940468
Impaired mast cell development and innate immunity in Mac-1 (CD11b/CD18, CR3)-deficient mice.Q42425832
Interferon-induced transcriptional and post-transcriptional modulation of factor H and C4 binding-protein synthesis in human monocytesQ42859242
Integrin CD11c/CD18 α-chain phosphorylation is functionally important.Q42905780
Human complement C3 deficiency: Th1 induction requires T cell-derived complement C3a and CD46 activation.Q43630649
Human skin mast cells express complement factors C3 and C5.Q44986589
Complement receptor type 1 (CR1, CD35) is a potent inhibitor of B-cell functions in rheumatoid arthritis patients.Q45966283
Isolation and characterization of macrophage-derived C1q and its similarities to serum C1q.Q46192544
CR3 is the dominant phagocytotic complement receptor on human dendritic cells.Q47242705
Human C′3: Evidence for the Liver as the Primary Site of SynthesisQ47802638
Levels of expression of complement regulatory proteins CD46, CD55 and CD59 on resting and activated human peripheral blood leucocytesQ50335848
Control of complement synthesis and secretion in bronchoalveolar and peritoneal macrophages.Q53958725
Human monocyte-derived dendritic cells are a source of several complement proteins.Q54593034
Organ-specific contribution to circulating C7 levels by the bone marrow and liver in humansQ57089607
Extrahepatic secreted complement C3 contributes to circulating C3 levels in humansQ57089621
Complement components, regulators and receptors are produced by human monocyte-derived dendritic cells.Q64890884
Synthesis of complement components C5, C6, C7, C8 and C9 in vitro by human monocytes and assembly of the terminal complement complexQ69629002
P433issue2
P304page(s)183-194
P577publication date2017-03-24
P1433published inClinical and Experimental ImmunologyQ15716708
P1476titleProduction of complement components by cells of the immune system
P478volume188

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