Interleukin-10: new perspectives on an old cytokine

scientific article

Interleukin-10: new perspectives on an old cytokine is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1600-065X.2008.00706.X
P8608Fatcat IDrelease_g4pp6zxorncwleuqiab5yb2a4q
P3181OpenCitations bibliographic resource ID1700725
P932PMC publication ID2724982
P698PubMed publication ID19161426

P2093author name stringDavid M Mosser
Xia Zhang
P2860cites workDistal enhancer elements transcribe intergenic RNA in the IL-10 family gene clusterQ81512281
STAT-1-mediated repression of monocyte interleukin-10 gene expression in vivoQ82570904
Interleukin-10 and the interleukin-10 receptorQ24290912
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophagesQ24630719
Functional cooperation of simian virus 40 promoter factor 1 and CCAAT/enhancer-binding protein beta and delta in lipopolysaccharide-induced gene activation of IL-10 in mouse macrophagesQ28185612
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10Q56930023
In the absence of endogenous IL-10, mice acutely infected with Toxoplasma gondii succumb to a lethal immune response dependent on CD4+ T cells and accompanied by overproduction of IL-12, IFN-gamma and TNF-alphaQ57339973
Relation of an Interleukin-10 Promoter Polymorphism to Graft-versus-Host Disease and Survival after Hematopoietic-Cell TransplantationQ58814550
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruziQ58843169
Evidence for a dual mechanism for IL-10 suppression of TNF-alpha production that does not involve inhibition of p38 mitogen-activated protein kinase or NF-kappa B in primary human macrophagesQ64378877
Differential regulation of the stability of cytokine mRNAs in lipopolysaccharide-activated blood monocytes in response to interleukin-10Q71246017
IL-10 enhances NK cell proliferation, cytotoxicity and production of IFN-gamma when combined with IL-18Q73046049
Cyclic adenosine monophosphate-responsive elements are involved in the transcriptional activation of the human IL-10 gene in monocytic cellsQ73129207
Interleukin-10 signaling blocks inhibitor of kappaB kinase activity and nuclear factor kappaB DNA bindingQ73133709
Regulation of lipopolysaccharide sensitivity by IFN regulatory factor-2Q73419660
Inhibitory and stimulatory effects of IL-10 on human CD8+ T cellsQ74411962
Interleukin-10-induced CD8 cell proliferationQ78197542
Molecular mechanisms of interleukin-10-mediated inhibition of NF-kappaB activity: a role for p50Q79369723
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chainQ28259983
The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokinesQ28509281
Expression of interleukin-10 in intestinal lymphocytes detected by an interleukin-10 reporter knockin tiger mouseQ28589701
BCL-3 and NF-kappaB p50 attenuate lipopolysaccharide-induced inflammatory responses in macrophagesQ28591859
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
Macrophage activation and polarizationQ29616353
Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clonesQ29622840
Functional analysis of -571 IL-10 promoter polymorphism reveals a repressor element controlled by sp1.Q30434272
The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29.Q30445936
Interleukin-10 suppression of myeloid cell activation--a continuing puzzleQ33340529
The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.Q33703365
Interleukin-10 increases Th1 cytokine production and cytotoxic potential in human papillomavirus-specific CD8(+) cytotoxic T lymphocytesQ33804742
Proinflammatory effects of IL-10 during human endotoxemiaQ33914291
Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohn's Disease IL-10 Cooperative Study GroupQ33927770
Acute alcohol intake induces SOCS1 and SOCS3 and inhibits cytokine-induced STAT1 and STAT3 signaling in human monocytesQ33977596
Mechanisms of interleukin-10-mediated immune suppressionQ34285968
ERK activation following macrophage FcgammaR ligation leads to chromatin modifications at the IL-10 locusQ34428303
Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.Q34448382
Circuitry of nuclear factor kappaB signalingQ34514908
A phase I trial with transgenic bacteria expressing interleukin-10 in Crohn's diseaseQ34529230
Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B.Q34674471
A2A adenosine receptors and C/EBPbeta are crucially required for IL-10 production by macrophages exposed to Escherichia coliQ36007662
Adenosine augments IL-10 production by macrophages through an A2B receptor-mediated posttranscriptional mechanismQ36023602
Resolution of a chronic viral infection after interleukin-10 receptor blockadeQ36228023
CD4(+)CD25(-)Foxp3(-) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasisQ36229713
Conventional T-bet(+)Foxp3(-) Th1 cells are the major source of host-protective regulatory IL-10 during intracellular protozoan infection.Q36229731
Interleukin 10 pretreatment protects target cells from tumor- and allo-specific cytotoxic T cells and downregulates HLA class I expressionQ36364150
Anti-interleukin 10 receptor monoclonal antibody is an adjuvant for T helper cell type 1 responses to soluble antigen only in the presence of lipopolysaccharideQ36368582
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibodyQ36376567
c-maf promotes T helper cell type 2 (Th2) and attenuates Th1 differentiation by both interleukin 4-dependent and -independent mechanismsQ36401230
Ets-1, a functional cofactor of T-bet, is essential for Th1 inflammatory responsesQ36403225
IL-10 blockade facilitates DNA vaccine-induced T cell responses and enhances clearance of persistent virus infectionQ36509838
Pbx raises the DNA binding specificity but not the selectivity of antennapedia Hox proteinsQ36570588
Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolinQ36727319
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The JAK-STAT signaling pathway: input and output integrationQ36740971
Mast cell homeostasis: a fundamental aspect of allergic diseaseQ36789388
IL-19 and IL-20: two novel cytokines with importance in inflammatory diseasesQ36804414
T(H)1 cells control themselves by producing interleukin-10.Q36831662
Protein kinase R-dependent regulation of interleukin-10 in response to double-stranded RNA.Q36869485
NF-kappaB1 (p50) homodimers differentially regulate pro- and anti-inflammatory cytokines in macrophagesQ37096935
Dynamic and transient remodeling of the macrophage IL-10 promoter during transcriptionQ37097929
Post-transcriptional control of cytokine productionQ37113415
Cytokine signaling modules in inflammatory responsesQ37133450
Not always the bad guys: B cells as regulators of autoimmune pathologyQ37147738
Stat4-dependent, T-bet-independent regulation of IL-10 in NK cellsQ37210723
CD4+ T-regulatory cells: toward therapy for human diseases.Q37211300
Optimization of dendritic cell loading with tumor cell lysates for cancer immunotherapyQ37513293
A common factor regulates both Th1- and Th2-specific cytokine gene expressionQ37628403
Chromatin-level regulation of the IL10 gene in T cells.Q38337531
cAMP-induced Interleukin-10 promoter activation depends on CCAAT/enhancer-binding protein expression and monocytic differentiationQ38359482
Suppression of dendritic cell differentiation through cytokines released by Primary Effusion Lymphoma cellsQ39953809
Role of STAT3 in glucocorticoid-induced expression of the human IL-10 geneQ39993283
Delivery of biologically active anti-inflammatory cytokines IL-10 and IL-1ra in vivo by the Shigella type III secretion apparatusQ40005415
Activation of cyclic-AMP response element binding protein contributes to adiponectin-stimulated interleukin-10 expression in RAW 264.7 macrophagesQ40014726
Silencing of endogenous IL-10 in human dendritic cells leads to the generation of an improved CTL response against human melanoma associated antigenic epitope, MART-1 27-35.Q40016708
A role for mitogen-activated protein kinase and Ets-1 in the induction of interleukin-10 transcription by human immunodeficiency virus-1 Tat.Q40156071
Regulation of IL-10 gene expression in Th2 cells by Jun proteins.Q40460750
The p38 mitogen-activated kinase pathway regulates the human interleukin-10 promoter via the activation of Sp1 transcription factor in lipopolysaccharide-stimulated human macrophagesQ40816643
Role of Stat3 in lipopolysaccharide-induced IL-10 gene expression.Q40867360
A prominent role for Sp1 during lipopolysaccharide-mediated induction of the IL-10 promoter in macrophagesQ40902387
Cutting edge: clustered AU-rich elements are the target of IL-10-mediated mRNA destabilization in mouse macrophages.Q40968046
Homology of cytokine synthesis inhibitory factor (IL-10) to the Epstein-Barr virus gene BCRFI.Q41731198
Haplotype-independent costimulation of IL-10 secretion by SDF-1/CXCL12 proceeds via AP-1 binding to the human IL-10 promoterQ42731419
Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.Q42930229
Interleukin-10 expression in macrophages during phagocytosis of apoptotic cells is mediated by homeodomain proteins Pbx1 and Prep-1.Q42945685
Blocking the receptor for IL-10 improves antimycobacterial chemotherapy and vaccinationQ43958346
IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapyQ44075382
Epstein-Barr virus-encoded small RNA induces IL-10 through RIG-I-mediated IRF-3 signalingQ44318736
IL-10 induces IL-10 in primary human monocyte-derived macrophages via the transcription factor Stat3.Q44723708
Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel diseaseQ45876830
Haplotype associated with low interleukin-10 production in patients with severe asthmaQ47808922
IFN-alpha induces the human IL-10 gene by recruiting both IFN regulatory factor 1 and Stat3.Q47817002
Treatment of murine colitis by Lactococcus lactis secreting interleukin-10.Q49073992
Central nervous system expression of IL-10 inhibits autoimmune encephalomyelitisQ49142940
Cutting edge: biasing immune responses by directing antigen to macrophage Fc gamma receptors.Q52938612
Evidence for a Dual Mechanism for IL-10 Suppression of TNF-  Production That Does Not Involve Inhibition of p38 Mitogen-Activated Protein Kinase or NF- B in Primary Human MacrophagesQ52990151
Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.Q53587595
Identification of a macrophage-specific chromatin signature in the IL-10 locus.Q53667399
IFN-gamma suppresses IL-10 production and synergizes with TLR2 by regulating GSK3 and CREB/AP-1 proteins.Q54600671
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectinterleukinsQ194908
P304page(s)205-18
P577publication date2008-12-01
P1433published inImmunological ReviewsQ15724582
P1476titleInterleukin-10: new perspectives on an old cytokine
P478volume226

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Q37778876Inflammation and survival pathways: chronic lymphocytic leukemia as a model system
Q93047629Influenza Virus-Induced Robust Expression of SOCS3 Contributes to Excessive Production of IL-6
Q39185042Inhibition of B7-1 (CD80) by RhuDex® reduces lipopolysaccharide-mediated inflammation in human atherosclerotic lesions
Q47141979Interferon Lambda Genetics and Biology in Regulation of Viral Control
Q34753189Interferon regulatory factor 3 and type I interferons are protective in alcoholic liver injury in mice by way of crosstalk of parenchymal and myeloid cells.
Q37259195Interferon-dependent IL-10 production by Tregs limits tumor Th17 inflammation
Q39777872Interferon-gamma induction correlates with protection by DNA vaccine expressing E2 glycoprotein against classical swine fever virus infection in domestic pigs.
Q40252348Interferon-γ mediates anemia but is dispensable for fulminant toll-like receptor 9-induced macrophage activation syndrome and hemophagocytosis in mice
Q63369779Interleukin 10 mutant zebrafish have an enhanced interferon gamma response and improved survival against a Mycobacterium marinum infection
Q54233764Interleukin gene polymorphisms and susceptibility to HIV-1 infection: a meta-analysis
Q87379170Interleukin levels and their potential association with venous thromboembolism and survival in cancer patients
Q41175673Interleukin-10 Conjugation to Carboxylated PVP-Coated Silver Nanoparticles for Improved Stability and Therapeutic Efficacy
Q47151593Interleukin-10 and soluble tumor necrosis factor receptor II are potential biomarkers of Plasmodium falciparum infections in pregnant women: a case-control study from Nanoro, Burkina Faso
Q33767035Interleukin-10 attenuation of collagen-induced arthritis is associated with suppression of interleukin-17 and retinoid-related orphan receptor γt production in macrophages and repression of classically activated macrophages
Q36565665Interleukin-10 gene polymorphisms are associated with freedom from treatment failure for patients with Hodgkin lymphoma
Q34357788Interleukin-10 haplotype may predict survival and relapse in resected non-small cell lung cancer
Q38747005Interleukin-10 haplotypes are not associated with acute cerebral ischemia or high-risk transcranial Doppler in a newborn cohort of 395 children with sickle cell anemia
Q37626939Interleukin-10 inhibits bone resorption: a potential therapeutic strategy in periodontitis and other bone loss diseases.
Q45301623Interleukin-10 involvement in exposure to low dose of benzene
Q82261735Interleukin-10 is expressed in HepG2.2.15 cells and regulated by STAT1 pathway
Q33631177Interleukin-10 mediated autoregulation of murine B-1 B-cells and its role in Borrelia hermsii infection
Q37164783Interleukin-10 prevents epithelial cell apoptosis by regulating IFNγ and TNFα expression in rhesus macaque colon explants.
Q34505654Interleukin-10 reduces the pathology of mdx muscular dystrophy by deactivating M1 macrophages and modulating macrophage phenotype
Q39270069Interleukin-10-1082A/G polymorphism and diabetic nephropathy: a meta-analysis
Q55013923Interleukin-10-Producing DC-10 Is a Unique Tool to Promote Tolerance Via Antigen-Specific T Regulatory Type 1 Cells.
Q54618534Interleukin-10-induced gene expression and suppressive function are selectively modulated by the PI3K-Akt-GSK3 pathway.
Q34486748Interleukin-10: an anti-inflammatory marker to target atherosclerotic lesions via PEGylated liposomes.
Q34361584Intraindividual long term stability and response corridors of cytokines in healthy volunteers detected by a standardized whole-blood culture system for bed-side application
Q50974260Intratumor OX40 stimulation inhibits IRF1 expression and IL-10 production by Treg cells while enhancing CD40L expression by effector memory T cells.
Q91756150Intravenous immunoglobulin (IVIg) or IVIg-treated macrophages reduce DSS-induced colitis by inducing macrophage IL-10 production
Q44680490Intravenous immunoglobulin skews macrophages to an anti-inflammatory, IL-10-producing activation state
Q34671059Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes
Q92308530Involvement of Interleukin-10 in Analgesia of Electroacupuncture on Incision Pain
Q35103995Involvement of Interleukin-10 in the Anti-Inflammatory Effect of Sanyinjiao (SP6) Acupuncture in a Mouse Model of Peritonitis
Q47567715Knockdown expression of IL-10Rα gene inhibits PRRSV replication and elevates immune responses in PBMCs of Tibetan pig in vitro
Q35059053Knockdown of HMGB1 in tumor cells attenuates their ability to induce regulatory T cells and uncovers naturally acquired CD8 T cell-dependent antitumor immunity
Q54977569LPS-Induced Inflammation Abolishes the Effect of DYRK1A on IkB Stability in the Brain of Mice.
Q35649843Lack of Association between Interleukin-10 Gene Polymorphisms and Graft Rejection Risk in Kidney Transplantation Recipients: A Meta-Analysis
Q37665341Lack of an association between a functional polymorphism in the interleukin-6 gene promoter and breast cancer risk: a meta-analysis involving 25,703 subjects
Q38181968Lack of association between IL-4 -588C>T polymorphism and NHL susceptibility
Q34594582Lack of interleukin-10-mediated anti-inflammatory signals and upregulated interferon gamma production are linked to increased intestinal epithelial cell apoptosis in pathogenic simian immunodeficiency virus infection
Q41772104Lck regulates IL‐10 expression in memory‐like Th1 cells
Q35329183Leishmania-infected macrophages are targets of NK cell-derived cytokines but not of NK cell cytotoxicity
Q90699538Macrophage and Tumor Cell Cross-Talk Is Fundamental for Lung Tumor Progression: We Need to Talk
Q34299710Macrophage cytokines: involvement in immunity and infectious diseases
Q33789327Macrophage death and defective inflammation resolution in atherosclerosis
Q92511732Macrophages Are Key Regulators of Stem Cells during Skeletal Muscle Regeneration and Diseases
Q51270292Macrophages and the Recovery from Acute and Chronic Inflammation.
Q57490861Mapping Determinants of Cytokine Signaling via Protein Engineering
Q34893320Matrix protein CCN1 induced by bacterial DNA and CpG ODN limits lung inflammation and contributes to innate immune homeostasis
Q34554210Mechanisms regulating monocyte CXCL8 secretion in neurocysticercosis and the effect of antiparasitic therapy
Q34467518Medroxyprogesterone acetate differentially regulates interleukin (IL)-12 and IL-10 in a human ectocervical epithelial cell line in a glucocorticoid receptor (GR)-dependent manner
Q53291169Minimal change disease: a “two-hit” podocyte immune disorder?
Q54977795Mitochondrial function - gatekeeper of intestinal epithelial cell homeostasis.
Q41985907Modulation of inflammasome-mediated pulmonary immune activation by type I IFNs protects bone marrow homeostasis during systemic responses to Pneumocystis lung infection
Q36661312Modulation of neoplastic gene regulatory pathways by the RNA-binding factor AUF1
Q40222984Modulation of the Host Environment by Human Cytomegalovirus with Viral Interleukin 10 in Peripheral Blood.
Q41325733Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy.
Q36041225Molecular mechanisms in genetically defined autoinflammatory diseases: disorders of amplified danger signaling
Q34872953Molecular mechanisms of alcoholic liver disease: innate immunity and cytokines
Q36983304Monitoring dendritic cell and cytokine biomarkers during remission prior to relapse in patients with FLT3-ITD acute myeloid leukemia
Q35047570More than skin deep: functional genomic basis for resistance to amphibian chytridiomycosis
Q34837867Multi-scale modeling predicts a balance of tumor necrosis factor-α and interleukin-10 controls the granuloma environment during Mycobacterium tuberculosis infection
Q59136421Multicellular Crosstalk Between Exosomes and the Neurovascular Unit After Cerebral Ischemia. Therapeutic Implications
Q38175584Multifarious determinants of cytokine receptor signaling specificity.
Q37989553Multiple pregnancy failures: an immunological paradigm
Q34121805Murine Kupffer cells are protective in total hepatic ischemia/reperfusion injury with bowel congestion through IL-10.
Q90707366Mutant Huntingtin affects toll-like receptor 4 intracellular trafficking and cytokine production in mast cells
Q38162229NFκB function and regulation in cutaneous T-cell lymphoma
Q90377640Nalbuphine, a kappa opioid receptor agonist and mu opioid receptor antagonist attenuates pruritus, decreases IL-31, and increases IL-10 in mice with contact dermatitis
Q36021837Neural reflexes in inflammation and immunity
Q38167771Neuropathic pain and cytokines: current perspectives
Q38301843Neuroprotective and anti-inflammatory mechanisms are activated early in optic neuritis
Q55010389Omega-3 Fatty Acid Supplementation Improves Endothelial Function in Primary Antiphospholipid Syndrome: A Small-Scale Randomized Double-Blind Placebo-Controlled Trial.
Q52309503Oncolytic viruses as engineering platforms for combination immunotherapy.
Q91705205Oral immunization with LacVax® OmpA induces protective immune response against Shigella flexneri 2a ATCC 12022 in a murine model
Q40844897Orf virus IL-10 reduces monocyte, dendritic cell and mast cell recruitment to inflamed skin
Q34294123Outer membrane protein A (OmpA) of Shigella flexneri 2a induces TLR2-mediated activation of B cells: involvement of protein tyrosine kinase, ERK and NF-κB.
Q57285031P2X antagonists inhibit HIV-1 productive infection and inflammatory cytokines IL-10 and IL-1β in a human tonsil explant model
Q37547862Paclitaxel inhibits the hyper-activation of spleen cells by lipopolysaccharide and induces cell death
Q38395906Pathogenesis of childhood idiopathic nephrotic syndrome: a paradigm shift from T-cells to podocytes
Q41994372Pathogenic Role of Macrophages in Intradermal Infection of Methicillin-Resistant Staphylococcus aureus in Thermally Injured Mice
Q54341932Periplasmic delivery of biologically active human interleukin-10 in Escherichia coli via a sec-dependent signal peptide.
Q26768280Pharmacological- and non-pharmacological therapeutic approaches in inflammatory bowel disease in adults
Q24300186Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages
Q43602017Placebo-controlled randomized clinical trial on the immunomodulating activities of low- and high-dose bromelain after oral administration - new evidence on the antiinflammatory mode of action of bromelain.
Q35876806Placental Malaria: Decreased Transfer of Maternal Antibodies Directed to Plasmodium falciparum and Impact on the Incidence of Febrile Infections in Infants
Q36389162Plasma IL-10 Levels to Guide Antiviral Prophylaxis Prevention of Late-Onset Cytomegalovirus Disease, in High Risk Solid Kidney and Liver Transplant Recipients
Q34659528Plasma RANTES, IL-10, and IL-8 levels in non-small-cell lung cancer patients treated with EGFR-TKIs.
Q91742459Podoplanin neutralization improves cardiac remodeling and function after acute myocardial infarction
Q42104268Polymorphism of IL-10 gene promoter region: association with T cell proliferative responses after acellular pertussis vaccination in adults
Q87876744Polymorphism of IL-10 receptor β affects the prognosis of multiple myeloma patients treated with thalidomide and/or bortezomib
Q42144212Polymorphisms of IL-10 affect the severity and prognosis of myelodysplastic syndrome
Q40600415Porcine circovirus type 2 increases interleukin-1beta and interleukin-10 production via the MyD88-NF-kappa B signaling pathway in porcine alveolar macrophages in vitro
Q34065213Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements
Q37216851Pre-B cell colony enhancing factor (PBEF), a cytokine with multiple physiological functions
Q24597706Progress and problems in understanding and managing primary Epstein-Barr virus infections
Q64957016Protein Phosphatase 1α and Cofilin Regulate Nuclear Translocation of NF-κB and Promote Expression of the Anti-Inflammatory Cytokine Interleukin-10 by T Cells.
Q36759999RNA helicase signaling is critical for type i interferon production and protection against Rift Valley fever virus during mucosal challenge
Q39571255Recombinant protein yield in rice seed is enhanced by specific suppression of endogenous seed proteins at the same deposit site
Q58009872Recycling endosome-dependent and -independent mechanisms for IL-10 secretion in LPS-activated macrophages
Q34635319Reduced IL-10 production in fetal type II epithelial cells exposed to mechanical stretch is mediated via activation of IL-6-SOCS3 signaling pathway
Q26773786Regulation of epithelial-mesenchymal transition by tumor-associated macrophages in cancer
Q28477869Regulation of interleukin-10 receptor ubiquitination and stability by beta-TrCP-containing ubiquitin E3 ligase
Q38602859Regulator Versus Effector Paradigm: Interleukin-10 as Indicator of the Switching Response
Q37072801Regulatory B cells (B10 cells) have a suppressive role in murine lupus: CD19 and B10 cell deficiency exacerbates systemic autoimmunity
Q34143986Regulatory B cells: Evidence, developmental origin and population diversity
Q97521548Regulatory T Cells in Pregnancy: It Is Not All About FoxP3
Q37621070Regulatory T cells and inhibitory cytokines in autoimmunity
Q55515862Reprogramming the murine colon cancer microenvironment using lentivectors encoding shRNA against IL-10 as a component of a potent DC-based chemoimmunotherapy.
Q89622533Reverting Immune Suppression to Enhance Cancer Immunotherapy
Q33785696Role of Interleukin-10 in Acute Brain Injuries.
Q54254089Role of MDA-7/IL-24 a Multifunction Protein in Human Diseases.
Q92239407Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection
Q88968512Role of cytokines and inflammation in heart function during health and disease
Q37735773Role of cytokines as mediators and regulators of microglial activity in inflammatory demyelination of the CNS.
Q34262223Role of interleukin 10 transcriptional regulation in inflammation and autoimmune disease
Q28082878Role of the immunogenic and tolerogenic subsets of dendritic cells in multiple sclerosis
Q38060836Roles of IL-10 in ocular inflammations: a review.
Q37192160Salivary and serum IL-10, TNF-α, TGF-β, VEGF levels in oropharyngeal squamous cell carcinoma and correlation with HPV and EBV infections
Q35007984Secretory expression of biologically active human Herpes virus interleukin-10 analogues in Escherichia coli via a modified Sec-dependent transporter construct
Q21142706Selection for genetic variation inducing pro-inflammatory responses under adverse environmental conditions in a Ghanaian population
Q36588933Sepsis in AIDS patients: clinical, etiological and inflammatory characteristics
Q38135863Septic shock: desperately seeking treatment
Q39901740Serum immune markers and disease progression in an incident Parkinson's disease cohort (ICICLE-PD).
Q83610554Serum profile of pro- and anti-inflammatory cytokines in rats following implantation of low-temperature plasma-modified titanium plates
Q99594573Shift work influences the outcomes of Chlamydia infection and pathogenesis
Q35595895Significance of decreased serum interleukin-10 levels in the progression of cerebral infarction
Q61758824Significance of −1082A/G polymorphism of IL10 gene for progression of colorectal cancer and IL-10 expression
Q35723929Somatostatin Improved B Cells Mature in Macaques during Intestinal Ischemia-Reperfusion
Q51151188Sound exposure-induced cytokine gene transcript profile changes in captive bottlenose dolphin (Tursiops truncatus) blood identified by a probe-based qRT-PCR.
Q90340960Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth
Q26861391Spinal interleukin-10 therapy to treat peripheral neuropathic pain
Q33987080Staphylococcal enterotoxins stimulate lymphoma-associated immune dysregulation.
Q37454396Staphylococcus aureus-dependent septic arthritis in murine knee joints: local immune response and beneficial effects of vaccination
Q89965617Streptococcal Extracellular Membrane Vesicles Are Rapidly Internalized by Immune Cells and Alter Their Cytokine Release
Q36519827Successful use of mRNA-nucleofection for overexpression of interleukin-10 in murine monocytes/macrophages for anti-inflammatory therapy in a murine model of autoimmune myocarditis
Q91987534Systemic interleukin 10 levels indicate advanced stages while interleukin 17A levels correlate with reduced survival in esophageal adenocarcinomas
Q31032531T-helper cell-mediated proliferation and cytokine responses against recombinant Merkel cell polyomavirus-like particles
Q35220162TLR9 ligands induce S100A8 in macrophages via a STAT3-dependent pathway which requires IL-10 and PGE2.
Q92633796TYK2 in Tumor Immunosurveillance
Q39649085Targeted nanoparticles containing the proresolving peptide Ac2-26 protect against advanced atherosclerosis in hypercholesterolemic mice
Q38196752Targeting IL-10 in auto-immune diseases
Q49496393Targeting cytokines for morphine tolerance: a narrative review.
Q37952796Targeting the tumor microenvironment by immunotherapy: part 2.
Q33918355Temporal anomalies in immunological gene expression in a time series of wild mice: signature of an epidemic?
Q27002441The -1082A>G polymorphism in promoter region of interleukin-10 and risk of digestive cancer: a meta-analysis
Q56767037The Compensatory Immune-Regulatory Reflex System (CIRS) in Depression and Bipolar Disorder
Q97541445The E3 ubiquitin ligase Itch deficiency promotes antigen-driven B-cell responses in mice
Q59806800The Interleukin-10 Family of Cytokines and Their Role in the CNS
Q38315987The Role of Macrophages in Promoting and Maintaining Homeostasis at the Fetal-Maternal Interface.
Q54617429The STATus of PD-L1 (B7-H1) on tolerogenic APCs.
Q44928641The analysis of immunological profiles in wild animals: a case study on immunodynamics in the field vole, Microtus agrestis.
Q53295921The associations between two polymorphisms in the interleukin-10 gene promoter and breast cancer risk
Q38008355The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells
Q47630841The cytokines and micro-environment of fracture haematoma: Current evidence
Q89884719The effects of IL-8, IL- 6, and IL-1 on the risk of celiac disease: a Bayesian regression analysis
Q38449629The glomerular permeability factors in idiopathic nephrotic syndrome
Q34672100The histone deacetylase inhibitors vorinostat and romidepsin downmodulate IL-10 expression in cutaneous T-cell lymphoma cells.
Q54217822The immunogenicity and protection effect of an inactivated coxsackievirus A6, A10, and A16 vaccine against hand, foot, and mouth disease.
Q42124225The influence of IgG density and macrophage Fc (gamma) receptor cross-linking on phagocytosis and IL-10 production
Q85235656The interferon-alpha and interleukin-10 responses in neonates differ from adults, and their production remains partial throughout the first 18 months of life
Q34239802The interleukin-6 -174G/C polymorphism and prostate cancer risk: a systematic review and meta-analysis
Q38615362The many faces of FcγRI: implications for therapeutic antibody function
Q47779902The maternal microbiome during pregnancy and allergic disease in the offspring
Q36040645The p38 MAP Kinase Family as Regulators of Proinflammatory Cytokine Production in Degenerative Diseases of the CNS.
Q37841258The regulation of thymic stromal lymphopoietin in gut immune homeostasis
Q34422017The role of dendritic cells in tissue-specific autoimmunity.
Q37050929The role of the vascular dendritic cell network in atherosclerosis
Q49933333The vaccine adjuvant alum promotes IL-10 production that suppresses Th1 responses.
Q52665595Tolerogenic Dendritic Cells in Solid Organ Transplantation: Where Do We Stand?
Q33917198Transcription of the activating receptor NKG2D in natural killer cells is regulated by STAT3 tyrosine phosphorylation.
Q36101959Transcriptome analysis reveals regional and temporal differences in mucosal immune system development in the small intestine of neonatal calves
Q34430041Trichodysplasia spinulosa-associated polyomavirus (TSV) and Merkel cell polyomavirus: correlation between humoral and cellular immunity stronger with TSV
Q88195028Trophoblast-derived CXCL16 induces M2 macrophage polarization that in turn inactivates NK cells at the maternal-fetal interface
Q42242747Type I interferon plays opposing roles in cytotoxicity and interferon-γ production by natural killer and CD8 T cells after influenza A virus infection in mice.
Q35832131Ubiquitination of CD86 is a key mechanism in regulating antigen presentation by dendritic cells
Q35093049Variants of the IL-10 gene associate with muscle strength in elderly from rural Africa: a candidate gene study
Q40167695Vascular leakage in dengue hemorrhagic Fever is associated with dengue infected monocytes, monocyte activation/exhaustion, and cytokines production
Q35022016Vasculogenic conditioning of peripheral blood mononuclear cells promotes endothelial progenitor cell expansion and phenotype transition of anti-inflammatory macrophage and T lymphocyte to cells with regenerative potential.
Q27324510Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice
Q35077633Virally expressed interleukin-10 ameliorates acute encephalomyelitis and chronic demyelination in coronavirus-infected mice
Q30436621Virus-encoded homologs of cellular interleukin-10 and their control of host immune function
Q37697636Vitamin D insufficiency: implications for the immune system
Q41050177Yoga, Meditation and Mind-Body Health: Increased BDNF, Cortisol Awakening Response, and Altered Inflammatory Marker Expression after a 3-Month Yoga and Meditation Retreat
Q34044736β-Arrestin 2 negatively regulates Toll-like receptor 4 (TLR4)-triggered inflammatory signaling via targeting p38 MAPK and interleukin 10.

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