Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells

scientific article published on August 1, 1990

Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P819ADS bibcode1990PNAS...87.6208L
P356DOI10.1073/PNAS.87.16.6208
P953full work available at URLhttps://europepmc.org/articles/PMC54502
https://europepmc.org/articles/PMC54502?pdf=render
https://pnas.org/doi/pdf/10.1073/pnas.87.16.6208
P932PMC publication ID54502
P698PubMed publication ID1696720
P5875ResearchGate publication ID21458497

P2093author name stringT. G. Lee
M. G. Katze
A. G. Hovanessian
J. Tomita
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The cellular 68,000-Mr protein kinase is highly autophosphorylated and activated yet significantly degraded during poliovirus infection: implications for translational regulation.Q36827533
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Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infectionQ37522288
Monoclonal antibodies to an interferon-induced Mr 68,000 protein and their use for the detection of double-stranded RNA-dependent protein kinase in human cellsQ37522386
Translational control by adenovirus: lack of virus-associated RNAI during adenovirus infection results in phosphorylation of initiation factor eIF-2 and inhibition of protein synthesisQ37682636
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A type 1 phosphoprotein phosphatase active with phosphorylated Mr = 68,000 initiation factor 2 kinaseQ42026719
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Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.Q42518461
A mechanism for the control of protein synthesis by adenovirus VA RNAI.Q44228079
Characterization of a specific kinase inhibitory factor produced by vaccinia virus which inhibits the interferon-induced protein kinaseQ45795607
Regulation of a protein synthesis initiation factor by adenovirus virus-associated RNA.Q45844438
Reduced activity of the interferon-induced double-stranded RNA-dependent protein kinase during a heat shock stress.Q53514299
Mechanism of interferon action. Activation of the human P1/eIF-2 alpha protein kinase by individual reovirus s-class mRNAs: s1 mRNA is a potent activator relative to s4 mRNAQ64379048
The binding of double-stranded RNA and adenovirus VAI RNA to the interferon-induced protein kinaseQ64379280
Modification of protein synthesis initiation factors and the shut-off of host protein synthesis in adenovirus-infected cellsQ64379290
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinaseQ64380153
2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expressionQ68131450
Autophosphorylation of the protein kinase dependent on double-stranded RNAQ68778559
Vaccinia specific kinase inhibitory factor prevents translational inhibition by double-stranded RNA in rabbit reticulocyte lysateQ69613112
A GDP/GTP exchange factor essential for eukaryotic initiation factor 2 cycling in Ehrlich ascites tumor cells and its regulation by eukaryotic initiation factor 2 phosphorylationQ70828889
2B or not 2B: regulation of the catalytic utilization of eIF-2Q71219239
Purification of the eukaryotic initiation factor 2-eukaryotic initiation factor 2B complex and characterization of its guanine nucleotide exchange activity during protein synthesis initiationQ71666510
P433issue16
P407language of work or nameEnglishQ1860
P304page(s)6208-6212
P577publication date1990-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePurification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells
P478volume87

Reverse relations

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