Interferon, Mx, and viral countermeasures

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Interferon, Mx, and viral countermeasures is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.CYTOGFR.2007.06.001
P698PubMed publication ID17683972

P50authorFriedemann WeberQ40182480
P2093author name stringGeorg Kochs
Otto Haller
P2860cites workInhibition of the interferon-inducible protein kinase PKR by HCV E2 proteinQ22010192
ISG20, a new interferon-induced RNase specific for single-stranded RNA, defines an alternative antiviral pathway against RNA genomic virusesQ24295036
Viruses as hijackers of PML nuclear bodiesQ24300060
Inhibition of retinoic acid-inducible gene I-mediated induction of beta interferon by the NS1 protein of influenza A virusQ24311228
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon inductionQ24318426
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virusQ24336255
Viral immediate-early proteins abrogate the modification by SUMO-1 of PML and Sp100 proteins, correlating with nuclear body disruptionQ24527246
The vaccinia virus soluble alpha/beta interferon (IFN) receptor binds to the cell surface and protects cells from the antiviral effects of IFN.Q24527590
Resistance to virus infection conferred by the interferon-induced promyelocytic leukemia proteinQ24531436
Dissociation of a MAVS/IPS-1/VISA/Cardif-IKKepsilon molecular complex from the mitochondrial outer membrane by hepatitis C virus NS3-4A proteolytic cleavageQ24546084
Alpha interferon induces distinct translational control programs to suppress hepatitis C virus RNA replicationQ24551046
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoterQ24558779
Activation of TBK1 and IKKvarepsilon kinases by vesicular stomatitis virus infection and the role of viral ribonucleoprotein in the development of interferon antiviral immunityQ24562025
A new pathway of translational regulation mediated by eukaryotic initiation factor 3Q24595576
Human papillomavirus 16 E6 oncoprotein binds to interferon regulatory factor-3 and inhibits its transcriptional activityQ24599944
Inborn resistance of ice to orthomyxoviruses.Q40101870
Thogoto virus lacking interferon-antagonistic protein ML is strongly attenuated in newborn Mx1-positive but not Mx1-negative miceQ40163331
Severe acute respiratory syndrome coronavirus open reading frame (ORF) 3b, ORF 6, and nucleocapsid proteins function as interferon antagonistsQ40208162
mda-5, but not RIG-I, is a common target for paramyxovirus V proteins.Q40218590
Inhibition of interferon signaling by the Kaposi's sarcoma-associated herpesvirus full-length viral interferon regulatory factor 2 protein.Q40311533
Binding of the influenza A virus NS1 protein to PKR mediates the inhibition of its activation by either PACT or double-stranded RNA.Q40319046
Role of double-stranded RNA and Npro of classical swine fever virus in the activation of monocyte-derived dendritic cellsQ40375175
Fascination with 2-5A-Dependent RNase: A Unique Enzyme That Functions in Interferon Action*Q40393376
N(pro) of classical swine fever virus is an antagonist of double-stranded RNA-mediated apoptosis and IFN-alpha/beta inductionQ40393486
Identification of the rabies virus alpha/beta interferon antagonist: phosphoprotein P interferes with phosphorylation of interferon regulatory factor 3.Q40416432
Inhibition of RNA polymerase II phosphorylation by a viral interferon antagonistQ40554311
Kaposi's sarcoma-associated herpesvirus-encoded vIRF-3 stimulates the transcriptional activity of cellular IRF-3 and IRF-7.Q40608568
MxA gene expression after live virus vaccination: a sensitive marker for endogenous type I interferonQ40703041
Correlation of interferon-induced expression of MxA mRNA in peripheral blood mononuclear cells with the response of patients with chronic active hepatitis C to IFN-alpha therapyQ40816503
Paramyxoviridae use distinct virus-specific mechanisms to circumvent the interferon responseQ40831794
Unique properties of a second human herpesvirus 8-encoded interferon regulatory factor (vIRF-2).Q40961025
Mx transgenic mice--animal models of healthQ40975130
Vaccinia virus-encoded cytokine receptor binds and neutralizes chicken interferon-gammaQ41012375
Double-stranded RNA is produced by positive-strand RNA viruses and DNA viruses but not in detectable amounts by negative-strand RNA virusesQ42425012
Mx protein: constitutive expression in 3T3 cells transformed with cloned Mx cDNA confers selective resistance to influenza virusQ42812948
Host gene influences sensitivity to interferon action selectively for influenza virusQ43535384
Thogoto virus ML protein suppresses IRF3 functionQ44180219
Viral stress-inducible protein p56 inhibits translation by blocking the interaction of eIF3 with the ternary complex eIF2.GTP.Met-tRNAiQ44529201
Missorting of LaCrosse virus nucleocapsid protein by the interferon-induced MxA GTPase involves smooth ER membranesQ44699375
The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humansQ45420643
Mx1 GTPase accumulates in distinct nuclear domains and inhibits influenza A virus in cells that lack promyelocytic leukaemia protein nuclear bodiesQ45610729
Resistance of mice to mouse-adapted influenza A virusQ45711577
Respiratory syncytial virus strain A2 is resistant to the antiviral effects of type I interferons and human MxA.Q45747101
Vaccinia virus encodes a soluble type I interferon receptor of novel structure and broad species specificityQ45785576
Activation of the ppp(A2'p)nA system in interferon-treated, herpes simplex virus-infected cells and evidence for novel inhibitors of the ppp(A2'p)nA-dependent RNaseQ45807691
Influenza virus resistance of wild mice: wild-type and mutant Mx alleles occur at comparable frequenciesQ45829963
Transgenic mice with intracellular immunity to influenza virusQ45850297
Genetic resistance to flaviviruses.Q53907696
Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways.Q54092575
Forward genetics of infectious diseases: immunological impactQ56941315
Impact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionQ24672548
GB virus B disrupts RIG-I signaling by NS3/4A-mediated cleavage of the adaptor protein MAVSQ24675888
Loss of interferon regulatory factor 3 in cells infected with classical swine fever virus involves the N-terminal protease, NproQ27469610
Human MxA protein protects mice lacking a functional alpha/beta interferon system against La crosse virus and other lethal viral infectionsQ27469723
Positional cloning of the murine flavivirus resistance geneQ27471857
A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory miceQ27471916
Inhibition of the protein kinase PKR by the internal ribosome entry site of hepatitis C virus genomic RNAQ27472970
Novel gene product of Thogoto virus segment 6 codes for an interferon antagonistQ27473101
The NPro Product of Bovine Viral Diarrhea Virus Inhibits DNA Binding by Interferon Regulatory Factor 3 and Targets It for Proteasomal DegradationQ27477650
Classical Swine Fever Virus Npro Interacts with Interferon Regulatory Factor 3 and Induces Its Proteasomal DegradationQ27478373
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responsesQ27860685
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphatesQ27861007
Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3Q27861127
Interferon-alpha induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6Q28115232
5'-Triphosphate RNA is the ligand for RIG-IQ28131726
VISA is an adapter protein required for virus-triggered IFN-beta signalingQ28131814
PKR; a sentinel kinase for cellular stressQ28137774
IKKepsilon and TBK1 are essential components of the IRF3 signaling pathwayQ28190704
Triggering the interferon antiviral response through an IKK-related pathwayQ28191761
Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene productQ28244407
IRFs: master regulators of signalling by Toll-like receptors and cytosolic pattern-recognition receptorsQ28260114
Characterization of the murine alpha interferon gene familyQ28588580
RNase L inhibitor (RLI) antisense constructions block partially the down regulation of the 2-5A/RNase L pathway in encephalomyocarditis-virus-(EMCV)-infected cellsQ28609293
RNase L inhibitor is induced during human immunodeficiency virus type 1 infection and down regulates the 2-5A/RNase L pathway in human T cellsQ28610868
Identification of genes differentially regulated by interferon alpha, beta, or gamma using oligonucleotide arraysQ28646554
Influenza A Virus Lacking the NS1 Gene Replicates in Interferon-Deficient SystemsQ29039793
Interferon-induced human MxA GTPase blocks nuclear import of Thogoto virus nucleocapsidsQ29040504
Stats: transcriptional control and biological impactQ29547776
Interferon-induced guanylate binding protein-1 (GBP-1) mediates an antiviral effect against vesicular stomatitis virus and encephalomyocarditis virusQ33177702
TFIIH transcription factor, a target for the Rift Valley hemorrhagic fever virus.Q33198557
Functional analysis of human herpesvirus 8-encoded viral interferon regulatory factor 1 and its association with cellular interferon regulatory factors and p300.Q33649357
Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cellsQ33743055
Inhibition of Beta interferon induction by severe acute respiratory syndrome coronavirus suggests a two-step model for activation of interferon regulatory factor 3.Q33781480
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factorQ33784902
Role of the promyelocytic leukemia protein PML in the interferon sensitivity of lymphocytic choriomeningitis virusQ33842651
Suppression of the induction of alpha, beta, and lambda interferons by the NS1 and NS2 proteins of human respiratory syncytial virus in human epithelial cells and macrophages [corrected]Q37093418
The infected cell protein 0 of herpes simplex virus 1 dynamically interacts with proteasomes, binds and activates the cdc34 E2 ubiquitin-conjugating enzyme, and possesses in vitro E3 ubiquitin ligase activity.Q37116670
Induction of MxA gene expression by influenza A virus requires type I or type III interferon signalingQ38301869
Human herpesvirus 8 encodes an interferon regulatory factor (IRF) homolog that represses IRF-1-mediated transcription.Q38341017
Double-stranded RNA binding by a heterodimeric complex of murine cytomegalovirus m142 and m143 proteinsQ38761545
Thogoto virus matrix protein is encoded by a spliced mRNA.Q39585556
Characterization of a novel human herpesvirus 8-encoded protein, vIRF-3, that shows homology to viral and cellular interferon regulatory factorsQ39593162
Genetic evidence for an interferon-antagonistic function of rift valley fever virus nonstructural protein NSsQ39601913
Bovine respiratory syncytial virus nonstructural proteins NS1 and NS2 cooperatively antagonize alpha/beta interferon-induced antiviral responseQ39612134
PML mediates the interferon-induced antiviral state against a complex retrovirus via its association with the viral transactivatorQ39645402
Herpes simplex virus type 1 immediate-early protein ICP0 and is isolated RING finger domain act as ubiquitin E3 ligases in vitroQ39686108
Regulation of the double-stranded RNA-dependent protein kinase PKR by RNAs encoded by a repeated sequence in the Epstein-Barr virus genomeQ39718117
NSs protein of Rift Valley fever virus blocks interferon production by inhibiting host gene transcriptionQ39960501
Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinaseQ33886447
Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase LQ33887630
The vaccinia virus K3L gene product potentiates translation by inhibiting double-stranded-RNA-activated protein kinase and phosphorylation of the alpha subunit of eukaryotic initiation factor 2Q33930433
Inhibition of interferon-mediated antiviral responses by influenza A viruses and other negative-strand RNA virusesQ33932047
Functional classification of interferon-stimulated genes identified using microarraysQ33951179
Antivirally active MxA protein sequesters La Crosse virus nucleocapsid protein into perinuclear complexesQ34016778
Role and fate of PML nuclear bodies in response to interferon and viral infectionsQ34435571
The primary function of RNA binding by the influenza A virus NS1 protein in infected cells: Inhibiting the 2'-5' oligo (A) synthetase/RNase L pathwayQ34598589
Toll-like receptors and Type I interferonsQ34613816
Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signalingQ34648134
Reverse genetic generation of recombinant Zaire Ebola viruses containing disrupted IRF-3 inhibitory domains results in attenuated virus growth in vitro and higher levels of IRF-3 activation without inhibiting viral transcription or replicationQ34717075
Interferon-induced mx proteins: dynamin-like GTPases with antiviral activityQ34852388
Promyelocytic leukemia protein mediates interferon-based anti-herpes simplex virus 1 effectsQ35020024
Wild mice: an ever-increasing contribution to a popular mammalian model.Q35031148
Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity.Q35031966
The pathogenic NY-1 hantavirus G1 cytoplasmic tail inhibits RIG-I- and TBK-1-directed interferon responsesQ35101310
Murine cytomegalovirus m142 and m143 are both required to block protein kinase R-mediated shutdown of protein synthesisQ35101535
Evolution of the interferon tau genes and their promoters, and maternal-trophoblast interactions in control of their expressionQ35592235
Replication fitness determines high virulence of influenza A virus in mice carrying functional Mx1 resistance geneQ35800387
Inferences, questions and possibilities in Toll-like receptor signallingQ35829752
Vaccinia, cowpox, and camelpox viruses encode soluble gamma interferon receptors with novel broad species specificityQ35843985
A phylogenetically conserved RNA structure in the poliovirus open reading frame inhibits the antiviral endoribonuclease RNase L.Q35857644
The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-Q35964369
Viruses know it all: new insights into IFN networksQ36142963
The interferon response circuit: induction and suppression by pathogenic virusesQ36346824
Type 1 interferons and the virus-host relationship: a lesson in détente .Q36475884
Inhibition of PKR by RNA and DNA virusesQ36480640
IFN-lambda: novel antiviral cytokinesQ36492388
Degradation of the interferon-induced 68,000-M(r) protein kinase by poliovirus requires RNAQ36641030
RIG-I: tri-ing to discriminate between self and non-self RNA.Q36738647
Triggering the innate antiviral response through IRF-3 activationQ36774934
Adenovirus virus-associated RNA and translation controlQ36820396
Influenza virus-susceptible mice carry Mx genes with a large deletion or a nonsense mutationQ36847687
Genetic mapping of the Mx influenza virus resistance gene within the region of mouse chromosome 16 that is homologous to human chromosome 21.Q36882739
P433issue5-6
P304page(s)425-433
P577publication date2007-08-01
P1433published inCytokine and Growth Factor ReviewsQ15763303
P1476titleInterferon, Mx, and viral countermeasures
P478volume18