Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase

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Tat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase is …
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scholarly articleQ13442814

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P819ADS bibcode1990PNAS...87.8687G
P356DOI10.1073/PNAS.87.22.8687
P932PMC publication ID55024
P698PubMed publication ID2247437
P5875ResearchGate publication ID20909509

P2093author name stringA P Rice
M B Mathews
H D Robertson
S Gunnery
P2860cites workEfficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoterQ27861016
Control of the interferon-induced 68-kilodalton protein kinase by the HIV-1 tat gene productQ28244407
A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggsQ28274604
Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene productQ29615049
Vectors for selective expression of cloned DNAs by T7 RNA polymeraseQ29620230
HIV-1 Tat protein increases transcriptional initiation and stabilizes elongationQ29620799
Suppression of the translation defect phenotype specific for a virus-associated RNA-deficient adenovirus mutant in monkey cells by simian virus 40.Q33926830
Structural requirements of double-stranded RNA for the activation of 2‘,5‘-oligo(A) polymerase and protein kinase of interferon-treated HeLa cellsQ34221795
Human immunodeficiency virus 1 tat protein binds trans-activation-responsive region (TAR) RNA in vitroQ34303073
Complementation of adenovirus virus-associated RNA I gene deletion by expression of a mutant eukaryotic translation initiation factorQ34322100
Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeatQ34563887
Efficient trans-activation by the HIV-2 Tat protein requires a duplicated TAR RNA structureQ35835407
Activation of interferon-regulated, dsRNA-dependent enzymes by human immunodeficiency virus-1 leader RNA.Q35864756
Removal of double-stranded contaminants from RNA transcripts: synthesis of adenovirus VA RNAI from a T7 vectorQ35877665
Mutational analysis of the 5' non-coding region of human immunodeficiency virus type 1: effects of secondary structure on translationQ36062164
Effects of mutations in stem and loop regions on the structure and function of adenovirus VA RNAIQ36062230
ompT encodes the Escherichia coli outer membrane protease that cleaves T7 RNA polymerase during purificationQ36195130
Purification and properties of the replicative intermediate of the RNA bacteriophage R17Q36460473
Purification and activation of the double-stranded RNA-dependent eIF-2 kinase DAIQ36763912
The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAsQ36767369
Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAsQ36796132
Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence.Q36802812
A mechanism by which adenovirus virus-associated RNAI controls translation in a transient expression assayQ36834492
Construction and analysis of additional adenovirus substitution mutants confirm the complementation of VAI RNA function by two small RNAs encoded by Epstein-Barr virusQ36854251
An adenovirus mutant unable to express VAI RNA displays different growth responses and sensitivity to interferon in various host cell linesQ36901893
Adenovirus VAI RNA prevents phosphorylation of the eukaryotic initiation factor 2 alpha subunit subsequent to infectionQ37522288
Regulation of expression of human immunodeficiency virusQ37783139
Interferon and human immunodeficiency virus infectionQ38181269
Human immunodeficiency virus type 1 LTR TATA and TAR region sequences required for transcriptional regulationQ38345116
Regulatory pathways governing HIV-1 replicationQ38360638
Regulation of HIV and HTLV gene expressionQ39289382
Impact of virus infection on host cell protein synthesisQ39596383
A novel transcription property of SP6 and T7 RNA polymerases: dependence on template structure.Q40471595
Translational control mediated by eucaryotic initiation factor-2 is restricted to specific mRNAs in transfected cellsQ40659075
Adenovirus VA RNAI mediates a translational stimulation which is not restricted to the viral mRNAsQ41388647
Interferon-induced enzymatic activities and their role in the antiviral stateQ41674497
Escherichia coli ribonuclease III.Q41854975
Activation of double-stranded RNA-dependent kinase (dsl) by the TAR region of HIV-1 mRNA: a novel translational control mechanismQ42158761
Inhibition of mRNA binding to ribosomes by localized activation of dsRNA-dependent protein kinaseQ42445108
Characterization of the double-stranded RNA implicated in the inhibition of protein synthesis in cells infected with a mutant adenovirus defective for VA RNA.Q42518461
A mechanism for the control of protein synthesis by adenovirus VA RNAI.Q44228079
HIV-1 tat trans-activation requires the loop sequence within tar.Q44349676
Demonstration of virus-specific transcriptional activator(s) in cells infected with HTLV-III by an in vitro cell-free systemQ45029117
A developmentally regulated activity that unwinds RNA duplexesQ45204994
Regulation of mRNA accumulation by a human immunodeficiency virus trans-activator proteinQ45830211
Tat trans-activates the human immunodeficiency virus through a nascent RNA targetQ45847022
In vitro formation of short RNA polymerase II transcripts that terminate within the HIV-1 and HIV-2 promoter-proximal downstream regionsQ46119240
Structure, sequence, and position of the stem-loop in tar determine transcriptional elongation by tat through the HIV-1 long terminal repeatQ46674379
Catalytic RNA: a Nobel Prize for small village scienceQ48405443
Modification of protein synthesis initiation factors and the shut-off of host protein synthesis in adenovirus-infected cellsQ64379290
Adenovirus VAI RNA antagonizes the antiviral action of interferon by preventing activation of the interferon-induced eIF-2 alpha kinaseQ64380153
Sensitive methods for the detection and characterization of double helical ribonucleic acidQ66892121
A bulge structure in HIV-1 TAR RNA is required for Tat binding and Tat-mediated trans-activationQ68583028
Replication of RNA by the DNA-dependent RNA polymerase of phage T7Q69609657
Escherichia coli ribonuclease III cleavage sitesQ71452469
P433issue22
P407language of work or nameEnglishQ1860
P921main subjectHIV type 1Q18907320
P304page(s)8687-8691
P577publication date1990-11-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleTat-responsive region RNA of human immunodeficiency virus 1 can prevent activation of the double-stranded-RNA-activated protein kinase
P478volume87

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cites work (P2860)
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