scholarly article | Q13442814 |
review article | Q7318358 |
P356 | DOI | 10.1016/S0378-1119(99)00334-0 |
P698 | PubMed publication ID | 10521654 |
P50 | author | Carlos F. Menck | Q58336882 |
Luciana Dos Reis Vasques | Q73083629 | ||
P2093 | author name string | L da Veiga Pereira | |
A R Muotri | |||
P2860 | cites work | Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1 | Q24653515 |
A chimeric human immunodeficiency virus type 1 (HIV-1) minimal Rev response element-ribozyme molecule exhibits dual antiviral function and inhibits cell-cell transmission of HIV-1 | Q24683706 | ||
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans | Q27860867 | ||
A DNA enzyme that cleaves RNA | Q28111573 | ||
par-1, a gene required for establishing polarity in C. elegans embryos, encodes a putative Ser/Thr kinase that is asymmetrically distributed | Q28301842 | ||
In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence | Q29302322 | ||
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA. | Q30466758 | ||
Deoxyribozymes: new players in the ancient game of biocatalysis | Q33653402 | ||
Gene gating: a hypothesis | Q34192811 | ||
Triplex DNA structures. | Q34296747 | ||
Improved predictions of secondary structures for RNA | Q34310064 | ||
A kinetic and thermodynamic framework for the hammerhead ribozyme reaction | Q34337820 | ||
Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1. | Q34719998 | ||
Nuclease-resistant chimeric ribozymes containing deoxyribonucleotides and phosphorothioate linkages | Q34985249 | ||
Hepatitis B virus. New and evolving issues | Q35224757 | ||
Small catalytic RNAs | Q35671068 | ||
Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type I replication in permissive cell lines | Q35808611 | ||
Chimeric DNA-RNA hammerhead ribozymes have enhanced in vitro catalytic efficiency and increased stability in vivo | Q35927080 | ||
Multitarget-ribozyme directed to cleave at up to nine highly conserved HIV-1 env RNA regions inhibits HIV-1 replication--potential effectiveness against most presently sequenced HIV-1 isolates | Q35927204 | ||
Enhancement of ribozyme catalytic activity by a contiguous oligodeoxynucleotide (facilitator) and by 2'-O-methylation | Q35927260 | ||
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency | Q36376928 | ||
Hepatitis B: Evolving Epidemiology and Implications for Control | Q37102972 | ||
Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme | Q37298055 | ||
Anti-mRNA: specific inhibition of translation of single mRNA molecules | Q37579137 | ||
Ribozyme-mediated cleavage of c-fos mRNA reduces gene expression of DNA synthesis enzymes and metallothionein | Q37631307 | ||
Does antisense exist? | Q38289866 | ||
Dynamics of the internalization of phosphodiester oligodeoxynucleotides in HL60 cells | Q38319334 | ||
Electron paramagnetic resonance spectroscopic measurement of Mn2+ binding affinities to the hammerhead ribozyme and correlation with cleavage activity | Q38328958 | ||
Triplex DNA: fundamentals, advances, and potential applications for gene therapy | Q38347063 | ||
Inhibition of fibrillin 1 expression using U1 snRNA as a vehicle for the presentation of antisense targeting sequence | Q38347389 | ||
Gene therapy targeting cord blood-derived CD34+ cells from HIV-exposed infants: preclinical studies | Q39177405 | ||
Metal ions play a passive role in the hairpin ribozyme catalysed reaction | Q39721199 | ||
Hairpin ribozyme cleavage catalyzed by aminoglycoside antibiotics and the polyamine spermine in the absence of metal ions | Q39726035 | ||
Intracellular cleavage of hepatitis C virus RNA and inhibition of viral protein translation by hammerhead ribozymes | Q39775286 | ||
Localized RNAs and their functions | Q40385118 | ||
DNA Triplexes: Solution Structures, Hydration Sites, Energetics, Interactions, and Function | Q40392807 | ||
The secondary structure and sequence optimization of an RNA ligase ribozyme | Q40395435 | ||
Efficient hammerhead ribozyme-mediated cleavage of the structured hepatitis B virus encapsidation signal in vitro and in cell extracts, but not in intact cells. | Q40397070 | ||
Design of RNA enzymes distinguishing a single base mutation in RNA. | Q40453502 | ||
Ribozymes: biology, biochemistry, and implications for clinical medicine. | Q40456051 | ||
Targeted gene replacement. | Q40728488 | ||
Inhibition of HIV-1 replication by retroviral vectors expressing monomeric and multimeric hammerhead ribozymes | Q40884585 | ||
Human immunodeficiency virus type 1 reverse transcriptase and early events in reverse transcription | Q41125504 | ||
A ribozyme specifically suppresses transformation and tumorigenicity of Ha-ras-oncogene-transformed NIH/3T3 cell lines | Q41141669 | ||
A novel ribozyme target site located in the HIV-1 nef open reading frame | Q41203517 | ||
Inhibition of viral multiplication in cells chronically infected with mouse hepatitis virus by antisense RNA against the polymerase gene | Q41342172 | ||
Inhibition of viral multiplication by hammerhead ribozymes targeted against the polymerase gene of mouse hepatitis virus | Q41440656 | ||
Ribozyme mediated destruction of influenza A virus in vitro and in vivo | Q41477454 | ||
The New World of ribozymes | Q41515767 | ||
Nuclease resistant ribozymes with high catalytic activity | Q41524149 | ||
Inhibition of mouse hepatitis virus multiplication by antisense oligonucleotide, antisense RNA, sense RNA and ribozyme. | Q41585464 | ||
Inhibition of replication of HIV-1 by retroviral vectors expressing tat-antisense and anti-tat ribozyme RNA. | Q41603934 | ||
Colocalization of antisense RNAs and ribozymes with their target mRNAs | Q41693518 | ||
Role of divalent metal ions in the hammerhead RNA cleavage reaction | Q41963110 | ||
Ribozymes designed to inhibit transformation of NIH3T3 cells by the activated c-Ha-ras gene | Q42817127 | ||
Preformed ribozyme destroys tumour necrosis factor mRNA in human cells | Q44805881 | ||
A controlled, Phase 1 clinical trial to evaluate the safety and effects in HIV-1 infected humans of autologous lymphocytes transduced with a ribozyme that cleaves HIV-1 RNA. | Q44845726 | ||
Delta virus as a vector for the delivery of biologically-active RNAs: possibly a ribozyme specific for chronic hepatitis B virus infection | Q45128958 | ||
Intracellular inhibition of HIV-1 replication using a dual protein- and RNA-based strategy | Q45188274 | ||
Intracellular application of hairpin ribozyme genes against hepatitis B virus | Q45760765 | ||
T-cell mediated rejection of gene-modified HIV-specific cytotoxic T lymphocytes in HIV-infected patients | Q45876112 | ||
Development of a hammerhead ribozyme against bcl-2. I. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer | Q45883446 | ||
Gene therapy -- promises, problems and prospects | Q45883584 | ||
TKO'ed: lox, stock and barrel | Q46910453 | ||
Novel configurations of the hammerhead ribozyme: increased activity and reduced magnesium ion requirement. | Q54120354 | ||
A triploblast origin for Myxozoa? | Q55067453 | ||
Ribozyme therapeutics | Q56883937 | ||
A small catalytic oligoribonucleotide | Q59060304 | ||
A DNA metalloenzyme with DNA ligase activity | Q59060345 | ||
Antisense oligonucleotides: a new therapeutic principle | Q61687385 | ||
Kinetics of intermolecular cleavage by hammerhead ribozymes | Q67465203 | ||
Kinetic Characterization of Ribonuclease-Resistant 2′-Modified Hammerhead Ribozymes | Q67923126 | ||
Minimum ribonucleotide requirement for catalysis by the RNA hammerhead domain | Q68145732 | ||
Intracellular localization of messenger RNAs for cytoskeletal proteins | Q69485528 | ||
Isolation of active ribozymes from an RNA pool of random sequences using an anchored substrate RNA | Q71710742 | ||
Toward a Broad-Based Antisense Technology | Q71791174 | ||
Catalytic Activity of an RNA Molecule Prepared by Transcription in Vitro | Q72726486 | ||
Structure-mapping of the hairpin ribozyme. Magnesium-dependent folding and evidence for tertiary interactions within the ribozyme-substrate complex | Q72819689 | ||
RNAi in C. elegans: soaking in the genome sequence | Q77642002 | ||
Target site selection for an RNA-cleaving catalytic DNA | Q77759838 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | ribozyme | Q205858 |
gene therapy | Q213901 | ||
P304 | page(s) | 303-310 | |
P577 | publication date | 1999-09-01 | |
P1433 | published in | Gene | Q5531065 |
P1476 | title | Ribozymes and the anti-gene therapy: how a catalytic RNA can be used to inhibit gene function | |
P478 | volume | 237 |
Q41783724 | Anti-HBV hairpin ribozyme-mediated cleavage of target RNA in vitro |
Q39230650 | C-SPACE (cleavage-specific amplification of cDNA ends): a novel method of ribozyme-mediated gene identification |
Q34491418 | Coronary in-stent restenosis: current status and future strategies. |
Q34452681 | Delivery of novel macromolecular drugs against HIV-1. |
Q40539253 | Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites |
Q34417562 | Exploiting genetic alterations to design novel therapies for cancer |
Q34492788 | Genetic targeting of the renin-angiotensin system for long-term control of hypertension |
Q30953558 | HIV-1 LTR as a target for synthetic ribozyme-mediated inhibition of gene expression: site selection and inhibition in cell culture |
Q24514478 | Involvement of proteasome alpha-subunit PSMA7 in hepatitis C virus internal ribosome entry site-mediated translation |
Q40600748 | Preparation and identification of anti-transforming growth factor beta1 U1 small nuclear RNA chimeric ribozyme in vitro |
Q38307722 | Rev-binding aptamer and CMV promoter act as decoys to inhibit HIV replication |
Q40760040 | Ribozyme-mediated suppression of G protein gamma subunits |
Q43207089 | Substrate specificity and reaction kinetics of an X-motif ribozyme |
Q73420665 | The hammerhead ribozyme |
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