| scholarly article | Q13442814 |
| P50 | author | Frank Kirchhoff | Q15451512 |
| Jan Münch | Q90640213 | ||
| P2093 | author name string | Michael Schindler | |
| P2860 | cites work | Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS | Q22242658 |
| HIV-1 Nef impairs MHC class II antigen presentation and surface expression | Q22248080 | ||
| Endocytosis of major histocompatibility complex class I molecules is induced by the HIV–1 Nef protein | Q22251058 | ||
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| Mechanism for down-regulation of CD28 by Nef. | Q24291079 | ||
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| Human immunodeficiency virus type 1 Nef binds to tumor suppressor p53 and protects cells against p53-mediated apoptosis. | Q24292352 | ||
| Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling | Q24532104 | ||
| Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor zeta chain | Q24676619 | ||
| Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators | Q28203103 | ||
| Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients | Q28284190 | ||
| Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection | Q28304773 | ||
| The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c | Q28508087 | ||
| A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry | Q29617253 | ||
| Participation of p53 protein in the cellular response to DNA damage | Q29618319 | ||
| Importance of the nef gene for maintenance of high virus loads and for development of AIDS | Q29618369 | ||
| Simian immunodeficiency virus containing mutations in N-terminal tyrosine residues and in the PxxP motif in Nef replicates efficiently in rhesus macaques | Q30168517 | ||
| Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Nef-associated kinase and simian AIDS in rhesus macaques | Q30176158 | ||
| The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes | Q30176171 | ||
| Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques | Q30176465 | ||
| Nef enhances human immunodeficiency virus replication and responsiveness to interleukin-2 in human lymphoid tissue ex vivo. | Q33647181 | ||
| Induction of cell death in human immunodeficiency virus-infected macrophages and resting memory CD4 T cells by TRAIL/Apo2l | Q33849293 | ||
| The dynamics of CD4+ T-cell depletion in HIV disease | Q33942992 | ||
| Apoptosis occurs predominantly in bystander cells and not in productively infected cells of HIV- and SIV-infected lymph nodes | Q34297394 | ||
| Nef: agent of cell subversion | Q34552824 | ||
| Apoptosis as an HIV strategy to escape immune attack | Q35136008 | ||
| Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis | Q36231815 | ||
| Evasion of cytotoxic T lymphocyte (CTL) responses by nef-dependent induction of Fas ligand (CD95L) expression on simian immunodeficiency virus-infected cells. | Q36380292 | ||
| CD4 regulates susceptibility to Fas ligand- and tumor necrosis factor-mediated apoptosis | Q36400376 | ||
| HIV-1 directly kills CD4+ T cells by a Fas-independent mechanism | Q36400607 | ||
| NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope | Q36403868 | ||
| Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles. | Q36524357 | ||
| Vpr and Vpu are important for efficient human immunodeficiency virus type 1 replication and CD4+ T-cell depletion in human lymphoid tissue ex vivo | Q37596639 | ||
| Disrupting surfaces of nef required for downregulation of CD4 and for enhancement of virion infectivity attenuates simian immunodeficiency virus replication in vivo | Q39539413 | ||
| Efficient class I major histocompatibility complex down-regulation by simian immunodeficiency virus Nef is associated with a strong selective advantage in infected rhesus macaques | Q39604845 | ||
| Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS | Q39605895 | ||
| Highly pathogenic simian immunodeficiency virus mne variants that emerge during the course of infection evolve enhanced infectivity and the ability to downregulate CD4 but not class I major histocompatibility complex antigens | Q39683959 | ||
| Comprehensive analysis of nef functions selected in simian immunodeficiency virus-infected macaques | Q39992284 | ||
| Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. | Q40273924 | ||
| T cell apoptosis triggered via the CD3/T cell receptor complex and alternative activation pathways | Q40403162 | ||
| HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce anti-apoptotic signals | Q40770875 | ||
| Human immunodeficiency virus type 1 Nef protein sensitizes CD4(+) T lymphoid cells to apoptosis via functional upregulation of the CD95/CD95 ligand pathway. | Q40977621 | ||
| Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes? | Q41513765 | ||
| Apoptosis enhancement by the HIV-1 Nef protein. | Q42833248 | ||
| Ultraviolet light and osmotic stress: activation of the JNK cascade through multiple growth factor and cytokine receptors | Q46175993 | ||
| HIV induces lymphocyte apoptosis by a p53-initiated, mitochondrial-mediated mechanism | Q46780265 | ||
| TRAIL/Apo-2-ligand-induced apoptosis in human T cells. | Q54146049 | ||
| HIV-1 Nef protein protects infected primary cells against killing by cytotoxic T lymphocytes. | Q54148550 | ||
| CD4+ T-cell depletion in HIV infection: Are we closer to understanding the cause? | Q59375800 | ||
| Apoptosis in HIV infection | Q71802896 | ||
| HIV-1 Nef leads to inhibition or activation of T cells depending on its intracellular localization | Q72610545 | ||
| P433 | issue | 9 | |
| P921 | main subject | DNA damage | Q5205747 |
| apoptotic process | Q14599311 | ||
| P304 | page(s) | 5489-5498 | |
| P577 | publication date | 2005-05-01 | |
| P1433 | published in | Journal of Virology | Q1251128 |
| P1476 | title | Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism | |
| P478 | volume | 79 |
| Q91866655 | Acetylcholinesterase is not a generic marker of extracellular vesicles |
| Q40078268 | Association of Nef with p21-activated kinase 2 is dispensable for efficient human immunodeficiency virus type 1 replication and cytopathicity in ex vivo-infected human lymphoid tissue |
| Q34544718 | Cell-to-cell transmission can overcome multiple donor and target cell barriers imposed on cell-free HIV. |
| Q51689992 | Chromosomal radiosensitivity of HIV positive individuals. |
| Q36759728 | Comparative proteomic analysis of HIV-1 particles reveals a role for Ezrin and EHD4 in the Nef-dependent increase of virus infectivity |
| Q39593653 | Contribution of Vpu, Env, and Nef to CD4 down-modulation and resistance of human immunodeficiency virus type 1-infected T cells to superinfection |
| Q97519252 | Convergent Evolution of HLA-C Downmodulation in HIV-1 and HIV-2 |
| Q33966673 | Counteraction of HLA-C-mediated immune control of HIV-1 by Nef. |
| Q37072999 | Determinants in HIV-1 Nef for enhancement of virus replication and depletion of CD4+ T lymphocytes in human lymphoid tissue ex vivo |
| Q37722604 | Discovery of novel inhibitors of HIV-1 reverse transcriptase through virtual screening of experimental and theoretical ensembles |
| Q35943789 | Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection |
| Q41018174 | HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4+ T Lymphocytes |
| Q34573902 | HIV-1 Nef increases astrocyte sensitivity towards exogenous hydrogen peroxide |
| Q34617099 | HIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cells |
| Q34355599 | HIV-1 protein Nef inhibits activity of ATP-binding cassette transporter A1 by targeting endoplasmic reticulum chaperone calnexin |
| Q35092875 | HIV-1 transcripts use IRES-initiation under conditions where Cap-dependent translation is restricted by poliovirus 2A protease |
| Q36315429 | HIV-infected T cells are migratory vehicles for viral dissemination |
| Q34508801 | Identification of a 3-aminoimidazo[1,2-a]pyridine inhibitor of HIV-1 reverse transcriptase |
| Q36144187 | Increased susceptibility of CD4+ T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels |
| Q58751688 | Induction of HIF-1α by HIV-1 Infection in CD4 T Cells Promotes Viral Replication and Drives Extracellular Vesicle-Mediated Inflammation |
| Q33352696 | Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection |
| Q37057289 | Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner |
| Q35115692 | Lentiviral Nef proteins manipulate T cells in a subset-specific manner |
| Q91722858 | Longitudinal bioluminescent imaging of HIV-1 infection during antiretroviral therapy and treatment interruption in humanized mice |
| Q34303855 | Macrophages and their relevance in Human Immunodeficiency Virus Type I infection |
| Q93039460 | Mutations in the HIV-1 envelope glycoprotein can broadly rescue blocks at multiple steps in the virus replication cycle |
| Q36255107 | Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation |
| Q22252321 | Nef-Mediated Suppression of T Cell Activation Was Lost in a Lentiviral Lineage that Gave Rise to HIV-1 |
| Q39852042 | Nef-induced CD4 endocytosis in human immunodeficiency virus type 1 host cells: role of p56lck kinase |
| Q40069610 | Nef-mediated enhancement of virion infectivity and stimulation of viral replication are fundamental properties of primate lentiviruses |
| Q47561974 | Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors |
| Q57093831 | Preadaptation of Simian Immunodeficiency Virus SIVsmm Facilitated Env-Mediated Counteraction of Human Tetherin by Human Immunodeficiency Virus Type 2 |
| Q40168499 | Primary human immunodeficiency virus type 1 nef alleles show major differences in pathogenicity in transgenic mice |
| Q39470792 | Productive entry of HIV-1 during cell-to-cell transmission via dynamin-dependent endocytosis |
| Q27310788 | Rab27a controls HIV-1 assembly by regulating plasma membrane levels of phosphatidylinositol 4,5-bisphosphate |
| Q59358400 | Reduced Susceptibility to VIRIP-Based HIV-1 Entry Inhibitors Has a High Genetic Barrier and Severe Fitness Costs |
| Q40031727 | Selective downmodulation of HLA-A and -B by Nef alleles from different groups of primate lentiviruses |
| Q34051644 | Stimulation of the liver X receptor pathway inhibits HIV-1 replication via induction of ATP-binding cassette transporter A1 |
| Q27335125 | Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity |
| Q30393226 | Tetherin Antagonism by HIV-1 Group M Nef Proteins |
| Q30497822 | Tetherin restricts direct cell-to-cell infection of HIV-1. |
| Q28742774 | The HIV-1 Vpu viroporin inhibitor BIT225 does not affect Vpu-mediated tetherin antagonism |
| Q41265657 | Use of the CRISPR/Cas9 system as an intracellular defense against HIV-1 infection in human cells |
| Q40852753 | Visualizing the Behavior of HIV-Infected T Cells In Vivo Using Multiphoton Intravital Microscopy. |
| Q41557222 | Vpu is the main determinant for tetraspanin downregulation in HIV-1-infected cells. |
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