Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells

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Epstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKP1169
P932PMC publication ID2847232
P698PubMed publication ID20034954
P5875ResearchGate publication ID40774095

P50authorMing ChenQ42756715
P2093author name stringJen-Yang Chen
Ming-Tsan Liu
Yu-Ting Chang
Chih-Yeu Fang
Chung-Chun Wu
Wun-Shaing Wayne Chang
Yi-Ren Chen
Hsin-Wei Liao
Kuan-Lin Kuo
Hsin-Ying Chuang
Pei-Wen Wang
Chia-Huei Lee
Sheng-Ping Chou
Yu-Lian Chen
Shih-Lung Hsu
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Epstein-Barr virus provides a new paradigm: a requirement for the immediate inhibition of apoptosisQ24816875
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Three Epstein-Barr virus latency proteins independently promote genomic instability by inducing DNA damage, inhibiting DNA repair and inactivating cell cycle checkpointsQ39806215
The Epstein-Barr virus alkaline exonuclease BGLF5 serves pleiotropic functions in virus replicationQ39876597
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The DNase of gammaherpesviruses impairs recognition by virus-specific CD8+ T cells through an additional host shutoff functionQ40033016
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Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen induces chromosomal instability through inhibition of p53 functionQ40335991
The exonuclease and host shutoff functions of the SOX protein of Kaposi's sarcoma-associated herpesvirus are genetically separableQ40416504
Restriction-endonuclease-induced DNA double-strand breaks and chromosomal aberrations in mammalian cellsQ40486522
Multiple mechanisms account for genomic instability and molecular mutation in neoplastic transformation.Q40513186
The characterization of the EBV alkaline deoxyribonuclease cloned and expressed in E. coliQ40537781
Lytic KSHV infection inhibits host gene expression by accelerating global mRNA turnoverQ40578287
Virus particles produced by the herpes simplex virus type 1 alkaline nuclease null mutant ambUL12 contain abnormal genomesQ40583523
Promotion of microsatellite instability by hepatitis C virus core protein in human non-neoplastic hepatocyte cells.Q40588114
Epstein-Barr virus latent membrane protein 1 induces micronucleus formation, represses DNA repair and enhances sensitivity to DNA-damaging agents in human epithelial cells.Q40600441
The study of responses to 'model' DNA breaks induced by restriction endonucleases in cells and cell-free systems: achievements and difficultiesQ40645425
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Antibody response to Epstein-Barr-virus-specific DNase in 13 patients with nasopharyngeal carcinoma in Taiwan: a retrospective studyQ42101546
Kaposi's sarcoma-associated herpesvirus induction of chromosome instability in primary human endothelial cellsQ42328529
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Oncogenic transformation of murine C3H 10T1/2 cells resulting from DNA double-strand breaks induced by a restriction endonucleaseQ43051301
The human papillomavirus type 16 E6 and E7 oncoproteins independently induce numerical and structural chromosome instability.Q44527945
Characterization of Monoclonal Antibodies to the Zta and DNase Proteins of Epstein-Barr VirusQ45042290
Pre-S mutant surface antigens in chronic hepatitis B virus infection induce oxidative stress and DNA damageQ45631058
Site-directed mutagenesis in a conserved motif of Epstein-Barr virus DNase that is homologous to the catalytic centre of type II restriction endonucleasesQ45729005
Increased chromosomal alterations and micronuclei formation in human hepatoma HepG2 cells transfected with the hepatitis B virus HBX geneQ45731365
Expression of the DNase encoded by the BGLF5 gene of Epstein-Barr virus in nasopharyngeal carcinoma epithelial cells.Q45768282
Herpes simplex virus gene products involved in the induction of chromosomal aberrationsQ45834858
Recurrent chemical reactivations of EBV promotes genome instability and enhances tumor progression of nasopharyngeal carcinoma cells.Q46170131
The RAG-1/2 endonuclease causes genomic instability and controls CNS complications of lymphoblastic leukemia in p53/Prkdc-deficient mice.Q52109680
Cytological effects of kepone on Chinese hamster cellsQ52517054
A modified host-cell reactivation assay to measure repair of alkylating DNA damage for assessing risk of lung adenocarcinoma.Q53336069
The comet assay: a method to measure DNA damage in individual cellsQ64388028
Loss of heterozygosity on the short arm of chromosome 3 in nasopharyngeal carcinomaQ68306620
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Micronuclei, kinetochores and hypoploidy: tests with some agentsQ69569055
Genetic instability and tumorigenesis: introductionQ71936207
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectEpstein–Barr virusQ6900
P304page(s)1932-1949
P577publication date2009-12-23
P1433published inNucleic Acids ResearchQ135122
P1476titleEpstein-Barr virus DNase (BGLF5) induces genomic instability in human epithelial cells
P478volume38

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